Patents by Inventor Edward T. Cox

Edward T. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Receptor polypeptides and their production and uses
    Publication number: 20030166020
    Abstract: An isolated TGF-&bgr; supergene family (TSF) receptor polypeptide is provided. This polypeptide preferably is an inhibin/activin receptor polypeptide and has at least 75% sequence identity with the mature human inhibin/activin receptor sequence. Also provided is a method for purifying TGF-&bgr; supergene family members such as inhibin or activin using the polypeptide, and a method for screening for compounds with TGF-&bgr; supergene family member activity by contacting the compound with the polypeptide and detecting if binding has occurred and the compound is active.
    Type: Application
    Filed: July 10, 2002
    Publication date: September 4, 2003
    Applicant: Genentech, Inc.
    Inventors: Edward T. Cox, Jennie P. Mather, Mary B. Sliwkowski, Teresa K. Woodruff
  • Receptor polypeptides and their production and uses
    Patent number: 6455262
    Abstract: An isolated TGF-&bgr; supergene family (TSF) receptor polypeptide is provided. This polypeptide preferably is an inhibin/activin receptor polypeptide and has at least 75% sequence identity with the mature human inhibin/activin receptor sequence. Also provided is a method for purifying TGF-&bgr; supergene family members such as inhibin or activin using the polypeptide, and a method for screening for compounds with TGF-&bgr; supergene family member activity by contacting the compound with the polypeptide and detecting if binding has occurred and the compound is active.
    Type: Grant
    Filed: September 21, 1993
    Date of Patent: September 24, 2002
    Assignee: Genentech, Inc.
    Inventors: Edward T. Cox, Jennie P. Mather, Mary B. Sliwkowski, Teresa K. Woodruff
  • Detection and purification of activin polypeptide
    Patent number: 5286654
    Abstract: An isolated TGF-.beta. supergene family (TSF) receptor polypeptide is provided. This polypeptide preferably is an inhibin/activin receptor polypeptide and has at least 75% sequence identity with the mature human inhibin/activin receptor sequence. Also provided is a method for purifying TGF-.beta. supergene family members such as inhibin or activin using the polypeptide, and a method for screening for compounds with TGF-.beta. supergene family member activity by contacting the compound with the polypeptide and detecting if binding has occurred and the compound is active.
    Type: Grant
    Filed: February 3, 1993
    Date of Patent: February 15, 1994
    Assignee: Genentech, Inc.
    Inventors: Edward T. Cox, Jennie P. Mather, Mary B. Sliwkowski, Teresa K. Woodruff
  • Receptor polypeptides and their production and uses
    Patent number: 5216126
    Abstract: An isolated TGF-.beta. supergene family (TSF) receptor polypeptide is provided. This polypeptide preferably is an inhibin/activin receptor polypeptide and has at least 75% sequence identity with the mature human inhibin/activin receptor sequence. Also provided is a method for purifying TGF-.beta. supergene family members such as inhibin or activin using the polypeptide, and a method for screening for compounds with TGF-.beta. supergene family member activity by contacting the compound with the polypeptide and detecting if binding has occurred and the compound is active.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: June 1, 1993
    Assignee: Genentech, Inc.
    Inventors: Edward T. Cox, Jennie P. Mather, Mary B. Sliwkowski, Teresa K. Woodruff