Patents by Inventor Edward T. Ryan

Edward T. Ryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vitro assays for detecting
    Patent number: 10288610
    Abstract: Provided are assays, kits and compositions for testing subjects, particularly asymptomatic subjects, to ascertain whether or not they are carriers of Salmonella enterica serotype Typhi. Methods for detecting the presence of Salmonella enterica serotype Typhi indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: May 14, 2019
    Assignees: THE GENERAL HOSPITAL CORPORATION, INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH (ICDDR,B), THE CHANGELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
    Inventors: Richelle Charles, Edward T. Ryan, Firdausi Qadri, Stephen Baker
  • Conjugating amines
    Patent number: 9616139
    Abstract: The disclosure provides directly conjugated polysaccharide vaccine molecules and methods related thereto.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: April 11, 2017
    Assignees: The General Hospital Corporation, The United States, as represented by the secretary, Department of Health and Human Services, International Centre for Diarrhoeal Disease Research, Bangladesh
    Inventors: Edward T. Ryan, Pavol Kovac, Firdausi Qadri, Peng Xu, Stephen B. Calderwood, Willie Frank Vann, Dwight Christopher Peterson
  • VITRO ASSAYS FOR DETECTING SALMONELLA ENTERICA SEROTYPE TYPHI
    Publication number: 20150293093
    Abstract: Provided are assays, kits and compositions for testing subjects, particularly asymptomatic subjects, to ascertain whether or not they are carriers of Salmonella enterica serotype Typhi. Methods for detecting the presence of Salmonella enterica serotype Typhi indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided.
    Type: Application
    Filed: November 12, 2013
    Publication date: October 15, 2015
    Inventors: Richelle Charles, Edward T. Ryan, Firdausi Qadri, Stephen Baker
  • CONJUGATING AMINES
    Publication number: 20150031863
    Abstract: The disclosure provides directly conjugated polysaccharide vaccine molecules and methods related thereto.
    Type: Application
    Filed: July 11, 2012
    Publication date: January 29, 2015
    Applicant: The General Hospital Corporation
    Inventors: Edward T. Ryan, Pavol Kovac, Firdausi Qadri, Peng Xu, Stephen B. Calderwood, Willie Frank Vann, Dwight Christopher Peterson
  • Use of the RTX secretion system to achieve heterologous polypeptide secretion by
    Patent number: 7049423
    Abstract: Compositions and methods for secreting large heterologous polypeptides are described.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: May 23, 2006
    Assignee: The General Hospital Corporation
    Inventor: Edward T. Ryan
  • Heterologous antigens in live cell V. cholerae strains
    Patent number: 6036953
    Abstract: Disclosed is a V. cholerae cell containing a DNA encoding a fusion polypeptide that includes a heterologous antigenic polypeptide sequence such as a portion of C. difficile toxin A. The fusion polypeptide also includes one of the following: (i) an E. coli hemolysin A subunit (wich is coexpressed with sequences encoding hemolysin B and D subunits); (ii) a secretion signal sequence and cholera toxin A2 subunit (which is coexpressed with cholera toxin B subunit); or (iii) cholera toxin B subunit.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 14, 2000
    Assignee: The General Hospital Corporation
    Inventors: Edward T. Ryan, Stephen B. Calderwood
  • Anodized aluminum having protective coating
    Patent number: 5439747
    Abstract: A coating composition and method for protecting anodized aluminum, and the coated product are disclosed, wherein the coating comprises a crosslinking agent; a film-forming resin selected from the group consisting of polyester polymers, thermosetting acrylic polymers, and mixtures thereof; and an epoxy silane. The combination provides exceptional adhesion of the coating to anodized surfaces as well as good hardness.
    Type: Grant
    Filed: November 22, 1993
    Date of Patent: August 8, 1995
    Assignee: PPG Industries, Inc.
    Inventors: Shelley D. Sturdevant, Edward T. Ryan, Bruce A. Connelly
  • Mirror protective composition comprising 2-mercaptothiazoline
    Patent number: 4880668
    Abstract: This invention relates to 2-mercaptothiazoline-containing resinous protective compositions which can be lead-free compositions for mirror-back coatings which are useful in reducing or preventing corrosion.
    Type: Grant
    Filed: November 14, 1989
    Date of Patent: November 14, 1989
    Assignee: PPG Industries, Inc.
    Inventors: Deborah E. Hayes, Alan B. Weissberg, Charles B. Friedlander, Edward T. Ryan