Patents by Inventor Edward W. Thomas

Edward W. Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of &agr;4&bgr;1 mediated cell adhesion
    Patent number: 6596752
    Abstract: The present invention relates to small molecules according to the formula [I]: which are potent inhibitors of &agr;4&bgr;1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing &agr;4&bgr;1 adhesion mediated conditions in a mammal such as a human.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: July 22, 2003
    Assignees: Tanabe Seiyaku Co., Ltd., Pharmacia & Upjohn Company
    Inventors: Thomas J. Lobl, Bradley R. Teegarden, Alexander Polinsky, Gilbert M. Rishton, Masafumi Yamagishi, Steven Tanis, Jed F. Fisher, Edward W. Thomas, Robert A. Chrusciel
  • Inhibitors of alpha 4beta1 mediated cell adhesion
    Publication number: 20030130349
    Abstract: The present invention relates to small molecules according to the formula [I]: 1
    Type: Application
    Filed: July 12, 2002
    Publication date: July 10, 2003
    Applicant: Tanabe Seiyaku Co., Ltd.
    Inventors: Thomas J. Lobl, Bradley R. Teegarden, Alexander Polinsky, Gilbert M. Rishton, Masafumi Yamagishi, Steven Tanis, Jed F. Fisher, Edward W. Thomas, Robert A. Chrusciel
  • Inhibitors of &agr;4&bgr;1 mediated cell adhesion
    Patent number: 6482849
    Abstract: The present invention relates to small molecules according to the formula [I]: which are potent inhibitors of &agr;4&bgr;1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing &agr;4&bgr;1 adhesion mediated conditions in a mammal such as a human.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: November 19, 2002
    Assignees: Tanabe Seiyaku Co., Ltd., Pharmacia & Upjohn Company
    Inventors: Thomas J. Lobl, Bradley R. Teegarden, Alexander Polinsky, Gilbert M. Rishton, Masafumi Yamagishi, Steven Tanis, Jed F. Fisher, Edward W. Thomas, Robert A. Chrusciel
  • Lipophilic polyamines useful for treating hypercholesterolemia
    Patent number: 5192798
    Abstract: This invention relates to novel lipophilic polyamines of formula I, the method of using these compounds to treat hypercholesterolemia, and intermediates thereto.Z.sub.1 --(CH.sub.2).sub.n --Y.sub.1 --X.sub.1 --R.sub.
    Type: Grant
    Filed: August 16, 1990
    Date of Patent: March 9, 1993
    Assignee: The Upjohn Company
    Inventors: James W. Aiken, Charles H. Spilman, Edward W. Thomas
  • 1,2,3-thiadiazole compounds, compositions and method of anti-thrombotic treatment
    Patent number: 5098918
    Abstract: Novel 1,2,3-thiadiazole compounds, new and old 1,2,3-thiadiazole compositions and method of anti-thrombotic treatment are systemically administered to a human or animal.
    Type: Grant
    Filed: June 4, 1987
    Date of Patent: March 24, 1992
    Assignee: The Upjohn Company
    Inventors: Edward W. Thomas, Ronald H. Rynbrandt, deceased