Patents by Inventor Edwin B. Villhauer

Edwin B. Villhauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of DPP-IV inhibitor to reduce hypoglycemic events
    Patent number: 8143217
    Abstract: The invention relates to a method to reduce the hypoglycemic events, especially sever hypoglycemic events resulting from insulin treatment, wherein the patient is treated with a Dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 18, 2006
    Date of Patent: March 27, 2012
    Assignee: Novartis AG
    Inventors: Boerk Balkan, David G Holmes, Thomas E Hughes, Edwin B Villhauer
  • Phosphinyloxy propanaminium inner salt derivatives
    Patent number: 5516767
    Abstract: Compounds of the formula ##STR1## where X.sub.1 and X.sub.2 are independently O or S, andR.sub.1 is as defined in the descriptionR.sub.2, R.sub.3, and R.sub.4 are each independently straight orbranched chain (C.sub.1-4)alkyl, and pharmaceutically acceptable salts, physiological hydrolysable esters, and pro-drug forms thereof are useful as hypoglycemic agents.
    Type: Grant
    Filed: January 17, 1995
    Date of Patent: May 14, 1996
    Assignee: Sandoz Ltd.
    Inventors: Robert C. Anderson, James D. Fraser, Howard C. Smith, Jeffrey W. Hughes, Edwin B. Villhauer, Gregory R. Bebernitz
  • Diaryl substituted cyclopentane and cyclopentene derivatives
    Patent number: 4845129
    Abstract: The invention discloses certain diaryl substituted cyclopentane and cyclopentene derivatives useful as PAF inhibitors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibiting PAF-induced blood platelet aggregation, PAF-mediated broncho-constriction and extravasation, PAF-induced hypotension, PAF-induced ischemic bowel disease and PAF-mediated, endotoxin induced lug injury.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: July 4, 1989
    Assignee: Sandoz Pharm. Corp.
    Inventors: Robert C. Anderson, William J. Houlihan, Howard C. Smith, Edwin B. Villhauer