Abstract: A cleaning and lubricant formulation for use on spindles on cotton picker or harvesting machines that simultaneously cleans and lubricates the surface of the spindles. The formulation features a major proportion of water and amounts of unsaturated fatty acids, glycol ether and alcohol solvents, nonionic surfactant, amide cosurfactant, and polycarboxylic acid. An alkalizing agent is added to control the pH of the resulting formulation. The cleaning and lubricant formulation exhibits excellent cleaning and lubrication properties without utilizing petroleum oil that can contaminate cotton fields, water supplies or the harvested cotton.