Abstract: A hair styling apparatus having a pair of closable jaws to engage a user's hair. The jaws have complementary shapes with a first said jaw defining a curved ridge and a second said jaw defining a curved recess. One or both of the jaws includes a heater such that, when said jaws are closed, hair is heated in a heating region between the ridge of the first jaw and the recess of said second jaw. The second jaw has a curved longitudinal surface having an active cooling region. The heating region is located on the forward curve and the active cooling region is located on the reverse curve.

Abstract: A hair styling apparatus comprising a pair of closable jaws (20,22) to engage a user's hair. Said jaws (20,22) have complementary shapes with, a first said jaw (20) defining a curved ridge and a second said jaw (22) defining a curved recess. One or both of said jaws (20,22) includes a heater such that, when said jaws are closed, hair is heated in a heating region (16) between the ridge of said first jaw (20) and the recess of said second jaw (22). Said second jaw (22) has a curved longitudinal surface having an active cooling region (14). A transverse cross section through said second jaw (22) defines at least one S-shaped curve having a forward curve into which said ridge of said first jaw (20) fits, and a linked reverse curve bearing said active cooling region (14) on which hair may be cooled and curved. Said heating region (16) is located on said forward curve; and said active cooling region (14) is located on said reverse curve.

Abstract: An apparatus for dispensing a frozen confection is provided comprising: an insulated chamber (1) housing a container (3) of a frozen confection; a refrigeration system (8); a nozzle (4) having an inner end which is connected to the container (3); and an outer end which is located outside the insulated chamber; means for applying pressure to the frozen confection thereby to dispense it from the container (3); a cap (7) which can enclose the outer end (6) of the nozzle (4) when closed and which allows external access to the outer end (6) of the nozzle (4) when open; and one or more channels (12) which allow cold air to flow from the chamber into the region around the outer end of the nozzle; wherein the apparatus comprises a removable holder (10) that supports the container (3) and wherein the spaces between the container (3), the inside of the chamber and the underside of the holder form the one or more channels (12).

Abstract: The present application is directed to a peptides comprising an a-helix forming-amino acid sequence that binds a heat shock protein. Also included is a polypeptide comprising (a) a first peptide portion that comprises an ?-helix-forming amino acid sequence that binds a heat shock protein; and (b) at least one second peptide portion comprising an antigenic amino acid sequence and/or an a-helix-stabilizing amino acid sequence that increases the interaction of the first peptide portion with the heat shock protein. The present application also includes compositions comprising the peptides and/or polypeptides of present application and uses of the peptides and/or polypeptides of the present application for fractionating substances relevant for discovery, research or clinical analysis from a biological sample and as therapeutics.

Abstract: Embodiments of the present invention feature a method and apparatus for an energetics-based approach to screen and to characterize binding interactions between potential therapeutic (or diagnostic) agents and unknown target molecules. The methods and apparatus detect the occurrence of these reactions, the strength of the binding interaction and possibly the rate at which these processes take place.

Abstract: A load carrier rack for a vehicle including a base member mountable on a portion of the vehicle is disclosed. The load carrier rack can also include an upright leg extending from the base member, the upright leg being slidably received by the base member. The load carrier rack can also include an interference mechanism including interference surface, the interference mechanism configured to have at least an actuated configuration and a released configuration. In the actuated configuration, the interference surface is engaged with the upright leg to resist movement of the upright leg relative the base; and in the release configuration, the interference surface is disengaged from the upright leg to permit movement of the upright leg relative the base.

Abstract: An apparatus for dispensing a frozen confection is provided comprising: an insulated chamber (1) housing a container (3) of a frozen confection; a refrigeration system (8); a nozzle (4) having an inner end which is connected to the container (3); and an outer end which is located outside the insulated chamber; means for applying pressure to the frozen confection thereby to dispense it from the container (3; a cap (7) which can enclose the outer end (6) of the nozzle (4) when closed and which allows external access to the outer end (6) of the nozzle (4) when open; and one or more channels (12) which allow cold air to flow from the chamber into the region around the outer end of the nozzle; wherein the apparatus comprises a removable holder (10) that supports the container (3) and wherein the spaces between the container (3), the inside of the chamber and the underside of the holder form the one or more channels (12).

Abstract: The present application is directed to a peptides comprising an a-helix forming-amino acid sequence that binds a heat shock protein. Also included is a polypeptide comprising (a) a first peptide portion that comprises an ?-helix-forming amino acid sequence that binds a heat shock protein; and (b) at least one second peptide portion comprising an antigenic amino acid sequence and/or an a-helix-stabilizing amino acid sequence that increases the interaction of the first peptide portion with the heat shock protein. The present application also includes compositions comprising the peptides and/or polypeptides of present application and uses of the peptides and/or polypeptides of the present application for fractionating substances relevant for discovery, research or clinical analysis from a biological sample and as therapeutics.

Abstract: Embodiments of the present invention feature a method and apparatus for an energetics-based approach to screen and to characterize binding interactions between potential therapeutic (or diagnostic) agents and unknown target molecules. The methods and apparatus detect the occurrence of these reactions, the strength of the binding interaction and possibly the rate at which these processes take place.

Abstract: Embodiments of the present invention feature a method and apparatus for an energetics-based approach to screen and to characterize binding interactions between potential therapeutic (or diagnostic) agents and unknown target molecules. The methods and apparatus detect the occurrence of these reactions, the strength of the binding interaction and possibly the rate at which these processes take place.

Abstract: A system for practicing pitching includes a batter mannequin which is selectively movable to a right handed batting position or to a left handed batting position. A catcher mannequin is disposed behind home plate, and is selectively movable along a transverse path. The catcher mannequin has a mitt which may be selectively moved up or down. The various movements of the batter mannequin and the catcher mannequin may be controlled from a practice pitching area.

Abstract: A system for practicing pitching includes a batter mannequin which is selectively movable to a right handed batting position or to a left handed batting position. The batter also can be selectively moved toward and away from home plate, and has a head which automatically faces the pitcher. A catcher mannequin is disposed behind the batter mannequin, the catcher mannequin being selectively positionable along a transverse path. The catcher mannequin has a mitt which may be selectively positioned up or down. The various movements of the batter mannequin and the catcher mannequin are remotely controlled using a remote control unit.

Abstract: A system for practicing pitching includes a batter mannequin which is selectively movable to a right handed batting position or to a left handed batting position. The batter also can be selectively moved toward and away from home plate, and has a head which automatically faces the pitcher. A catcher mannequin is disposed behind the batter mannequin, the catcher mannequin being selectively positionable along a transverse path. The catcher mannequin has a mitt which may be selectively positioned up or down. The various movements of the batter mannequin and the catcher mannequin are remotely controlled using a remote control unit.

Abstract: A device for measuring heat flow from a first, second and third sample. The device includes a sample array. The sample array includes a base, a first receptacle, capable of containing the first sample, coupled to the base; a second receptacle, capable of containing the second sample, coupled to the base; a third receptacle, capable of containing a third sample, coupled to the base; a first sensor, in communication with the first receptacle, which detects a first heat flow from the first sample and converts the first heat flow into a first electronic signal; a second sensor, in communication with the second receptacle, which detects a second heat flow from the second sample and converts the second heat flow into a second electronic signal; and a third sensor, in communication with the third receptacle, which detects a third heat flow from the third sample and converts the third heat flow into a third electronic signal.

Abstract: An emergency lighting fixture combining the functions of an illuminated sign such as an exit sign and an emergency lighting unit integrated into one housing onto which one or more emergency lights can be mounted at predetermined locations of the housing, the combined emergency lighting structure providing both exit location information and ambient emergency lighting in a single cooperatively operating device.

Abstract: An emergency lighting fixture combining the functions of an illuminated sign such as an exit sign and an emergency lighting unit integrated into one housing onto which one or more emergency lights can be mounted at predetermined locations of the housing, the combined emergency lighting structure providing both exit location information and ambient emergency lighting in a single cooperatively operating device. The present device replaces bulky prior combinations of discrete exit signs and emergency lighting units which have been assembled together essentially as individual devices without integration into a single housing or without substantial integration of operational features, the housing of the present device being only slightly larger than standard exit signage.

Abstract: The invented apparatus includes at least one acoustic sensor, a mapping unit, a controller, and a transducer. The sensor is coupled to an object to be inspected for damage, and generates a sensed signal based on acoustic signal occurring in the object under an applied load, which signal may or may not be the sound of damage occurring in the object. The mapping unit is coupled to receive the sensed signal from the sensor, and generates damage data based thereon. The controller is coupled to receive the damage data from the mapping unit. Initially, the apparatus is in a passive mode in which the apparatus senses an acoustic signal from the object. If the damage data indicates that the object has incurred possible damage in the passive mode, the controller switches to active mode and outputs induced signal data. The transducer is coupled to the object as well as the controller, and induces acoustic signal in the object, based on the induced signal data.

Abstract: An emergency lighting fixture combining the functions of an illuminated sign such as an exit sign and an emergency lighting unit integrated into one housing onto which one or more emergency lights can be mounted at predetermined locations of the housing, the combined emergency lighting structure providing both exit location information and ambient emergency lighting in a single cooperatively operating device. The present device replaces bulky prior combinations of discrete exit signs and emergency lighting units which have been assembled together essentially as individual devices without integration into a single housing or without substantial integration of operational features, the housing of the present device being only slightly larger than standard exit signage.