Patents by Inventor Eeva-Marjatta Salonen

Eeva-Marjatta Salonen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Urokinase-type plasminogen activator receptor
    Publication number: 20030027981
    Abstract: A polypeptide presenting an epitope cross-reactive with an epitope of urokinase-type plasminogen activator receptor, and/or having uPA binding activity, is described.
    Type: Application
    Filed: January 8, 2001
    Publication date: February 6, 2003
    Inventors: Keld Dano, Francesco Blasi, Ann Louring Roldan, Maria Vittoria Cubellis, Maria Teresa Masucci, Ettore Appella, Wolf-Dieter Schleuning, Niels Behrendt, Ebbe Ronne, Peter Kristensen, Jari Pollanen, Eeva-Marjatta Salonen, Ross W. Stephens, Hannele Tapiovaara, Antti Vaheri, Lisbeth Birk Moller, Vincent Ellis, Leif Roge Lund, Michael Ploug, Charles Pyke, Laszlo Patthy
  • Urokinase-type plasminogen activator receptor
    Patent number: 6248712
    Abstract: Activation of plasminogen to plasmin is inhibited by preventing the binding of a receptor binding form of urokinase-type plasminogen activator to a urokinase-type plasminogen activator receptor in a mammal, thereby preventing the urokinase-type plasminogen activator from converting plasminogen into plasmin. DNA fragments which encode for soluble, active fragments of the urokinase-type plasminogen activator receptor are provided.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: June 19, 2001
    Assignee: Cancerforskningsfondet af 1989
    Inventors: Keld Danø, Francesco Blasi, Ann Louring Roldan, Maria Vittoria Cubellis, Maria Teresa Masucci, Ettore Appella, W.D. Schleuning, Niels Behrendt, Ebbe Rønne, Peter Kristensen, Jari Pöllänen, Eeva-Marjatta Salonen, Ross W. Stephens, Hannele Tapiovaara, Antti Vaheri, Lisbeth Birk Møller, Vincent Ellis, Leif Røge Lund, Michael Ploug, Charles Pyke, Lászl{acute over (o )} Patthy
  • Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
    Patent number: 5891664
    Abstract: Activation of plasminogen to plasma is inhibited by preventing the binding of a receptor binding form of urokinase-type plasminogen activator to a urokinase-type plasminogen activator receptor in a mammal, thereby preventing the urokinase-type plasminogen activator from converting plasminogen into plasmin. DNA fragments which encode for soluble, active fragments of the urokinase-type plasminogen activator are provided.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: April 6, 1999
    Assignee: Cancerforskningsfondet af 1989
    Inventors: Keld Dan.o slashed., Francesco Blasi, Ann Louring Roldan, Maria Vittoria Cubellis, Maria Teresa Masucci, Ettore Appella, Wolf-Dieter Schleuning, Niels Behrendt, Ebbe R.o slashed.nne, Peter Kristensen, Jari Pollanen, Eeva-Marjatta Salonen, Ross W. Stephens, Hannele Tapiovaara, Antti Vaheri, Lisbeth Birk M.o slashed.ller, Vincent Ellis, Leif R.o slashed.ge Lund, Michael Ploug, Charles Pyke, Laszlo Patthy
  • Diagnostic method, test kit, drug and therapeutic treatment for autoimmune diseases
    Patent number: 5700641
    Abstract: Synthesized telomeric sequences bind to and can be used for detecting anti-DNA antibodies in serum. Autoimmune diseases such as Lupus Erythematosus, Rheumatoid Arthritis, and Scleroderma, can be detected by detecting an elevated level of anti-DNA antibodies using telomeric sequences. Test kits for such detection are provided including immobilized telomeric sequences capable of binding anti-DNA antibodies. Pharmaceutical compositions for inhibiting or reducing the activity of anti-DNA antibodies contain an effective amount of telomeric sequences effective in inhibiting the antibodies specific to the patient treated.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: December 23, 1997
    Inventor: Eeva-Marjatta Salonen
  • Method of ophthalmic testing
    Patent number: 5192665
    Abstract: A method of determining the presence of epithelial lesions is provided wherein a sample of a body of fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred. A method for detecting allergic sensitivity is also disclosed.
    Type: Grant
    Filed: April 11, 1989
    Date of Patent: March 9, 1993
    Assignee: Labsystems, Oy
    Inventor: Eeva-Marjatta Salonen
  • Pharmaceutical preparation for promoting epithelial healing and prevention of epithelial destruction
    Patent number: 5112805
    Abstract: A method of determining the presence of epithelial lesions is provided wherein a sample of a body fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred.
    Type: Grant
    Filed: April 11, 1989
    Date of Patent: May 12, 1992
    Assignee: Labsystems, Oy
    Inventor: Eeva-Marjatta Salonen
  • Method for promoting epithelial healing and prevention of epitheliam destruction
    Patent number: 4849406
    Abstract: A method of determining the presence of epithelial lesions is provided wherein a sample of a body fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred.
    Type: Grant
    Filed: March 11, 1986
    Date of Patent: July 18, 1989
    Assignee: Labsystems Oy
    Inventor: Eeva-Marjatta Salonen