Patents by Inventor Efrat Kessler

Efrat Kessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Procollagen C-proteinase enhancer (PCPE) biomarker for bone formation
    Patent number: 8518656
    Abstract: A method of diagnosing fibrosis in a subject is provided, comprising the steps of: determining a level of PCPE in a body fluid sample obtained from said subject; and detecting an increased level of PCPE in said body fluid sample relative to a normal control level of PCPE, wherein said increased level of PCPE relative to normal control is indicative of fibrosis in said subject. Furthermore, methods for evaluating the pharmacological efficacy of a drug or a drug candidate in treatment of fibrosis in a patient and for monitoring change of fibrosis in a subject are provided.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: August 27, 2013
    Assignees: Ramot Tel-Aviv University Ltd., Tel Hashomer Medical Research Infrastructure and Services Ltd.
    Inventors: Shlomit Mesilaty-Gross, Yair Anikster, Ido Wolf, Efrat Kessler
  • PROCOLLAGEN C-PROTEINASE ENHANCER (PCPE) BIOMARKER FOR BONE FORMATION
    Publication number: 20120270246
    Abstract: A method of diagnosing fibrosis in a subject is provided, comprising the steps of: determining a level of PCPE in a body fluid sample obtained from said subject; and detecting an increased level of PCPE in said body fluid sample relative to a normal control level of PCPE, wherein said increased level of PCPE relative to normal control is indicative of fibrosis in said subject. Furthermore, methods for evaluating the pharmacological efficacy of a drug or a drug candidate in treatment of fibrosis in a patient and for monitoring change of fibrosis in a subject are provided.
    Type: Application
    Filed: December 2, 2011
    Publication date: October 25, 2012
    Applicants: RAMOT AT TEL-AVIV UNIVERSITY LTD., TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD, THE CHAIM SHEBA MEDICAL CENTER
    Inventors: Shlomit Mesilaty-Gross, Yair Anikster, Ido Wolf, Efrat Kessler
  • Ophthalmic preparations
    Patent number: 4613587
    Abstract: There are provided ophthalmic preparations against eye diseases caused by P. aeruginosa elastase or similar enzymes. The active ingredient is a 2-mercaptoacyl di- or tri-peptide obtained from suitable amino acids. There is further provided a process for the treatment of Pseudomonas keratitis by means of such compositions.
    Type: Grant
    Filed: July 10, 1984
    Date of Patent: September 23, 1986
    Assignees: Yeda Research and Development Co. Ltd., Ramot University Authority for Applied Research and Industrial Development Ltd.
    Inventors: Efrat Kessler, Abraham Spierer, Shmaryahum Blumberg