Abstract: A method of manufacturing a panel, provided with a frame of a synthetic material at least at one side edge face thereof, a laminate composed of a particled board core coated on either side with a coating, with reservation of a molding cavity along the entire or partial panel circumference for the frame to be formed, being applied in the bottom portion of a mold likewise containing a cover portion, after which the mold is closed, while the cover portion is sealingly clamped onto the bottom portion, after which a curing bi-component synthetic material foaming through exothermic reaction is admitted substantially pressure-less into the mold cavity and the panel is removed from the mold after curing, whereby the exothermic reaction of the bi-component synthetic material is utilized for increasing the pressure and the temperature in the molding cavity during the foaming and curing.