Abstract: Provided are thermodynamically stable particles encapsulating active ingredients for administering to humans and other living organisms.

Abstract: Provided is a composition for oral administration, the composition including: a dispersion medium including: an aqueous solution; and a dispersed phase including: a population of particles, each particle including: a core including: a first active ingredient; and an aqueous solution; a shell, substantially surrounding the core, the shell including: a lipophilic carrier; and a plurality of emulsifying agents; wherein the particle retards the release of the first active ingredient after consumption.

Abstract: The present invention provides compositions relating to nanoparticles, such as nanocapsules, that selectively target cells associated with diseases or disorders (e.g., cancer cells). The present invention further relates to methods relating to the said nanoparticles for imaging, detection, and treatment of diseases or disorders in a subject. The present invention additionally provides kits that find use in the practice of the methods of the invention.

Abstract: Provided is a composition including a dispersion medium including: an aqueous solution and a dispersed phase including a population of particles, each particle including an active ingredient.

Abstract: Provided is a method of encapsulation, the method including: providing a first mixture, the first mixture including: a first carrier; and a first active ingredient; applying heat to the first mixture until the first mixture reaches a first temperature; providing a second mixture, the second mixture including: a second carrier; and a first emulsifying agent; applying heat to the second mixture until the second mixture reaches a second temperature; mixing the first mixture with the second mixture to obtain a third mixture, wherein: the mixing is performed at a third temperature; and the third temperature is lower than the first temperature; and cooling the third mixture until the third mixture reaches a fourth temperature, wherein: the second carrier is in solid state at the fourth temperature.

Abstract: Provided is a process, including: extracting one or more hydrophobic active ingredients of a plant material using an extraction solvent; transferring the one or more hydrophobic active ingredients from the extraction solvent to a carrier solvent; encapsulating the one or more hydrophobic active ingredients in one or more nanoparticles; and dispersing the one or more nanoparticles in an aqueous suspension, wherein: the one or more nanoparticles have a Z-average diameter between 50 to 950 nanometers; the Z-average diameter of the one or more nanoparticles changes less than 20% when the aqueous suspension is incubated at 40° C. for four weeks; and the Z-average diameter of the one or more nanoparticles changes less than 20% when the aqueous suspension is incubated at 90° C. for 30 minutes.

Abstract: Provided is a bead for use in food or a beverage, the bead comprising: a core comprising: a continuous phase comprising: a lipophilic carrier, and a wax; a dispersed phase comprising: one or more particles, wherein each particle comprises: a first active ingredient, and a first polymer, and a first shell at least substantially surrounding the core.

Abstract: Provided is a process, including: extracting one or more hydrophobic active ingredients of a plant material using a first extraction solvent; and transferring the one or more hydrophobic active ingredients from the first extractant solution filtrate to a carrier solvent; encapsulating the one or more hydrophobic active ingredients in one or more nanoparticles; dispersing the one or more nanoparticles in an aqueous suspension; and adding the second eluant from the plant material to the aqueous suspension.

Abstract: Provided is an additive for food, a beverage, or a supplement, the additive comprising: a first phase comprising: a first filler and a second phase, the second phase comprising a second filler and a third phase, the third phase comprising a third filler and a fourth phase, the fourth phase comprising a fifth filler and a first active ingredient.

Abstract: Provided is a composition, including: an aqueous suspension, comprising: a first plurality of active ingredients, and one or more nanoparticles, wherein: the one or more nanoparticles encapsulate a second plurality of active ingredients; the second plurality of active ingredients are insoluble in the aqueous suspension; the one or more nanoparticles solubilize the second plurality of active ingredients in the aqueous suspension; and the one or more nanoparticles have a Z-average diameter between 50 to 950 nanometers.

Abstract: Provided is an aqueous solution as a continuous phase, the aqueous solution comprising: a first plurality of polymers; and a first plurality of active ingredients; and one or more nanoparticles, as a dispersed phase, the one or more nanoparticles comprising: a first plurality of carrier solvents; and a second plurality of active ingredients, wherein: the second plurality of active ingredients have at least 5 times higher absorption in-vivo when located inside the one or more nanoparticles compared to when administered in an aqueous solution.

Abstract: Provided is a process including: extracting a first plurality of active ingredients of a first plant material using a first extraction solvent; extracting a second plurality of active ingredients of a second plant material using a second extraction solvent; transferring the first plurality of active ingredients from the first extractant solution filtrate to a carrier solvent; encapsulating the first plurality of active ingredients in one or more nanoparticles; dispersing the one or more nanoparticles in an aqueous suspension; and adding the second eluant from the second plant material to the aqueous suspension.

Abstract: Provided is a process including: extracting a first plurality of active ingredients of a first plant material using an extraction solvent, wherein the extraction comprises: transferring the first plant material into a temperature-controlled reactor, adding the extraction solvent to the temperature-controlled reactor, thereby producing a first eluant from the first plant material, incubating the first eluant at a first selected temperature for a first duration of time, applying ultrasound waves on the first plant material to expedite the extraction of the first plurality of active ingredients of the first plant material, and running the first eluent through a filtration process to obtain a first extractant solution filtrate and a first separated solid plan material product; encapsulating the first plurality of active ingredients in one or more nanoparticles; and dispersing the first plurality of active ingredients in a non-aqueous suspension.

Abstract: Provided is a non-aqueous suspension, comprising: a first plurality of active ingredients, wherein: the first plurality of active ingredients are soluble in the non-aqueous suspension; and one or more nanoparticles, wherein: the one or more nanoparticles encapsulate a second plurality of active ingredients; the second plurality of active ingredients are insoluble in the non-aqueous suspension; the one or more nanoparticles solubilize the second plurality of active ingredients in the non-aqueous suspension; the one or more nanoparticles have a Z-average diameter between 50 to 950 nanometers; the Z-average diameter of the one or more nanoparticles changes less than 20% when the non-aqueous suspension is incubated at 40° C. for four weeks; and the Z-average diameter of the one or more nanoparticles changes less than 20% when the non-aqueous suspension is incubated at 90° C. for 30 minutes.

Abstract: Provided is a process of stabilizing active ingredients of plant materials in an aqueous suspension, the process including: extracting one or more active ingredients of a plant material using an extraction solvent, wherein the extraction of the one or more active ingredients of the plant materials comprises: transferring the plant material into a temperature-controlled reactor; adding the extraction solvent to the temperature-controlled reactor, thereby producing an eluant from the plant material; incubating the eluant at a first selected temperature for a pre-determined duration of time; and running the eluent through a filtration process to obtain an extractant solution filtrate and a separated solid plan material product; encapsulating the one or more active ingredients in one or more nanoparticles; and dispersing the one or more nanoparticles in an aqueous suspension.

Abstract: Provided is a composition including a dispersion medium including: an aqueous solution; a first active ingredient; a flavor agent; and a first type of polymer; and a dispersed phase including: a population of particles, each particle including: a core including: a second active ingredient a second type of polymer; and an aqueous solution; a shell, substantially surrounding the core, the shell including: a third type of polymer; a plurality of lipophilic carriers; and a third active ingredient; and a plurality of emulsifying agents.

Abstract: Provided is a composition including a first phase comprising a first filler; a second phase, the second phase comprising a second filler; and a third phase comprising a third filler; and a fourth phase comprising a fourth filler; and a first active ingredient, wherein the first active ingredient is selected from the group consisting of caffeine, Echinacea purpurea, Echinacea angustifolia, Echinacea pallida, Acmella oleracea, Helichrysum umbraculigerum, Radula marginata, kava, kanna, black truffle, Syzygium aromaticum, Rosmarinus oficinalis, basil, oregano, lavender, true cinnamon, malabathrum, cananga odorata, Riboflavin, theanine, Ginkgo Biloba, Bacopa, Rhodiola Rosea, and combinations thereof.

Abstract: Provided is a composition for oral administration, the composition including: a dispersion medium including: an aqueous solution; and a dispersed phase including: a population of particles, each particle including: a core including: a first active ingredient; and an aqueous solution; a shell, substantially surrounding the core, the shell including: a lipophilic carrier; and a plurality of emulsifying agents; wherein the particle retards the release of the first active ingredient after consumption.

Abstract: Provided is a composition for oral administration, the composition including: a dispersion medium including: an aqueous solution; and a dispersed phase including: a population of particles, each particle including: a core including: a first active ingredient; and an aqueous solution; a shell, substantially surrounding the core, the shell including: a lipophilic carrier; and a plurality of emulsifying agents; wherein the particle retards the release of the first active ingredient after consumption.

Abstract: Provided is a composition for oral administration, the composition including: a dispersion medium including: an aqueous solution; and a dispersed phase including: a population of particles, each particle including: a core including: a first active ingredient; and an aqueous solution; a shell, substantially surrounding the core, the shell including: a lipophilic carrier; and a plurality of emulsifying agents; wherein the particle retards the release of the first active ingredient after consumption.