Patents by Inventor Eiichiro Ono

Eiichiro Ono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190203246
    Abstract: There has been a demand for a new method for producing a steviol glycoside and steviol. The present invention provides a method for producing a steviol glycoside and/or steviol, the method comprising a step of breaking bonds of steviol glycoside: a glucosidic bond at position 13; a glucosyl ester bond at position 19; and/or a glycosidic bond in a side chain (excluding a rhamnoside bond).
    Type: Application
    Filed: May 25, 2017
    Publication date: July 4, 2019
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa OCHIAI, Eiichiro ONO
  • Publication number: 20180327798
    Abstract: The present invention provides a method for producing a steviol glycoside and/or steviol, said method including a step in which a steviol glycoside having at least one unbranched ?1,2-glycosidic bond is reacted with the glycosidase AOBGL1 and/or AOBGL3, or a variant thereof, so as to cleave the ?1,2-glycosidic bond.
    Type: Application
    Filed: October 28, 2016
    Publication date: November 15, 2018
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa OCHIAI, Eiichiro ONO
  • Publication number: 20180312892
    Abstract: The present invention provides a method for preparing a steviol glycoside and/or steviol comprising reacting glycosidase AOBGL1 and/or AOBGL3 or a variant thereof with a steviol glycoside having at least one monoglucoside bond and/or monoglucosyl ester bond, thereby cleaving said monoglucoside bond and/or monoglucosyl ester bond.
    Type: Application
    Filed: October 28, 2016
    Publication date: November 1, 2018
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Misa OCHIAI, Eiichiro ONO
  • Patent number: 10113155
    Abstract: The present invention provides steviol glycosyltransferase and a method for producing a steviol glycoside using this enzyme. The present invention provides a transformant transformed with a gene for steviol glycosyltransferase and a method for preparing such a transformant.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: October 30, 2018
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventor: Eiichiro Ono
  • Patent number: 10113154
    Abstract: The invention provides a method for producing steviol glycosides. The invention provides a transformant having introduced therein the steviol glucosyltransferase and a method for producing steviol glycosides using the transformant.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: October 30, 2018
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventor: Eiichiro Ono
  • Patent number: 10000783
    Abstract: Steviol glucosyltransferases and methods for producing steviol glycosides using the enzymes are provided. The present invention provides steviol glucosyltransferases and methods for producing steviol glycosides using the enzymes. The invention also provides transformants into which steviol glucosyltransferase genes are introduced and methods for preparing the transformants.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 19, 2018
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Eiichiro Ono, Misa Ochiai
  • Patent number: 9957539
    Abstract: A method for producing a hexenol glycoside using a hexenol glycosyltransferase. A transformant transformed with a gene encoding a hexenol glycosyltransferase and a method for preparing such a transformant.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: May 1, 2018
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventor: Eiichiro Ono
  • Publication number: 20180010160
    Abstract: The present invention provides a method for preparing a mogroside having no ?-1,6-glucoside bond comprising the step of reacting glycosidase ASBGL2, AOBGL2, AOBGL1, ASBGL1, or a variant thereof with a mogroside having at least one ?-1,6-glucoside bond, thereby cleaving said ?-1,6-glucoside bond.
    Type: Application
    Filed: January 19, 2016
    Publication date: January 11, 2018
    Applicant: Suntory Holdings Limited
    Inventors: Misa OCHIAI, Eiichiro ONO
  • Publication number: 20170335362
    Abstract: To provide a mogrol glycosyltransferase and a method for producing a mogrol glycoside using the enzyme. The present invention provides a mogrol glycosyltransferase and a method for producing a mogrol glycoside using the enzyme, and a transformant into which a mogrol glycosyltransferase gene is introduced and a method for preparing the transformant.
    Type: Application
    Filed: October 16, 2015
    Publication date: November 23, 2017
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Eiichiro ONO, Misa OCHIAI
  • Patent number: 9574182
    Abstract: The object of the present invention is to provide Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing a monoterpene glycoside by means of this enzyme. The present invention provides Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing a monoterpene glycoside by means of this enzyme. The present invention provides a transformant transformed with a gene for Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing such a transformant.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: February 21, 2017
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Eiichiro Ono, Nobuo Tsuruoka
  • Patent number: 9518282
    Abstract: The object of the present invention is to provide a novel method for producing a terpene 8-glycoside. The present invention provides a method for producing a terpene 8-glycoside by means of glycosyltransferase acting on the 8-position of terpenes. The present invention provides a transformant transformed with a gene for the glycosyltransferase acting on the 8-position of terpenes and a method for producing such a transformant. The present invention provides a plant modified to suppress the expression of a protein having glycosylation activity on the 8-position of a monoterpene compound.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: December 13, 2016
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Eiichiro Ono, Nobuo Tsuruoka
  • Publication number: 20160319317
    Abstract: The object of the present invention is to provide a method for producing a hexenol glycoside by means of hexenol glycosyltransferase. The present invention provides a method for producing a hexenol glycoside by means of hexenol glycosyltransferase. The present invention provides a transformant transformed with a gene for hexenol glycosyltransferase and a method for preparing such a transformant.
    Type: Application
    Filed: August 1, 2014
    Publication date: November 3, 2016
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventor: Eiichiro ONO
  • Publication number: 20150218533
    Abstract: The present invention provides steviol glycosyltransferase and a method for producing a steviol glycoside using this enzyme. The present invention provides a transformant transformed with a gene for steviol glycosyltransferase and a method for preparing such a transformant.
    Type: Application
    Filed: May 29, 2013
    Publication date: August 6, 2015
    Inventor: Eiichiro Ono
  • Publication number: 20150159188
    Abstract: Steviol glucosyltransferases and methods for producing steviol glycosides using the enzymes are provided. The present invention provides steviol glucosyltransferases and methods for producing steviol glycosides using the enzymes. The invention also provides transformants into which steviol glucosyltransferase genes are introduced and methods for preparing the transformants.
    Type: Application
    Filed: March 14, 2013
    Publication date: June 11, 2015
    Inventors: Eiichiro Ono, Misa Ochiai
  • Publication number: 20150140132
    Abstract: The object of the present invention is to provide Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing a monoterpene glycoside by means of this enzyme. The present invention provides Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing a monoterpene glycoside by means of this enzyme. The present invention provides a transformant transformed with a gene for Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing such a transformant.
    Type: Application
    Filed: February 5, 2013
    Publication date: May 21, 2015
    Inventors: Eiichiro Ono, Nobuo Tsuruoka
  • Publication number: 20150128306
    Abstract: The invention provides a method for producing steviol glycosides. The invention provides a transformant having introduced therein the steviol glucosyltransferase and a method for producing steviol glycosides using the transformant.
    Type: Application
    Filed: March 14, 2013
    Publication date: May 7, 2015
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventor: Eiichiro Ono
  • Publication number: 20140020137
    Abstract: The object of the present invention is to provide a novel method for producing a terpene 8-glycoside. The present invention provides a method for producing a terpene 8-glycoside by means of glycosyltransferase acting on the 8-position of terpenes. The present invention provides a transformant transformed with a gene for the glycosyltransferase acting on the 8-position of terpenes and a method for producing such a transformant. The present invention provides a plant modified to suppress the expression of a protein having glycosylation activity on the 8-position of a monoterpene compound.
    Type: Application
    Filed: December 27, 2011
    Publication date: January 16, 2014
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventors: Eiichiro Ono, Nobuo Tsuruoka
  • Patent number: 8628938
    Abstract: The present invention provides a novel UDP-glucuronosyltransferase and a polynucleotide encoding the same, for example, a polynucleotide comprising nucleotides 1 to 1359 of SEQ ID NO: 4, nucleotides 1 to 1365 of SEQ ID NO: 10, nucleotides 1 to 1371 of SEQ ID NO: 12, and nucleotides 1 to 1371 of SEQ ID NO: 22; or a polynucleotide encoding a protein having the amino acid sequence of SEQ ID NOS: 5, 11, 13 or 23. The invention provides a novel UDP-glucuronosyltransferase with a broad substrate specificity.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: January 14, 2014
    Assignee: Suntory Holdings Limited
    Inventors: Eiichiro Ono, Akio Noguchi, Yuko Fukui, Masako Mizutani
  • Patent number: 8435778
    Abstract: The present invention provides an enzyme having an activity of transferring a methyl group to lignans (a lignan methylation activity) (e.g., a protein comprising the amino acid sequence of SEQ ID NO: 2 or variants thereof); a gene encoding the enzyme (e.g., a polynucleotide comprising the nucleotide sequence of SEQ ID NO: 1 or variants thereof); a method for producing methylated lignans using the gene; and so on.
    Type: Grant
    Filed: May 13, 2010
    Date of Patent: May 7, 2013
    Assignee: Suntory Holdings Limited
    Inventors: Eiichiro Ono, Toshiaki Umezawa, Takefumi Hattori, Shiro Suzuki
  • Publication number: 20130040348
    Abstract: The present invention provides an enzyme having an activity of transferring a methyl group to lignans (a lignan methylation activity) (e.g., a protein comprising the amino acid sequence of SEQ ID NO:2 or variants thereof); a gene encoding the enzyme (e.g., a polynucleotide comprising the nucleotide sequence of SEQ ID NO:1 or variants thereof); a method for producing methylated lignans using the gene; and so on.
    Type: Application
    Filed: May 13, 2010
    Publication date: February 14, 2013
    Applicant: Suntory Holdings Limited
    Inventors: Eiichiro Ono, Toshiaki Umezawa, Takefumi Hattori, Shiro Suzuki