Patents by Inventor Eiji Imada

Eiji Imada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240150366
    Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 9, 2024
    Inventors: Kenichi KAWAGUCHI, Kazuyuki KURAMOTO, Tomoyoshi IMAIZUMI, Takahiro MORIKAWA, Mitsuaki OKUMURA, Sunao IMADA, Eiji KAWAMINAMI, Ryo SATO, Yohei SEKI, Hisao HAMAGUCHI, Hiroki ISHIOKA, Hiroki FUKUDOME, Ikumi KURIWAKI, Takeyuki NAGASHIMA
  • Patent number: 5116706
    Abstract: 1,2,4,5-Benzoylenebis(naphto[1,8-de]pyrimidine) compounds of the followig formula (I) or (II): ##STR1## wherein R and R' are, the same or different, hydrogen atom, a halogen atom, hydroxyl group, nitro group, cyano group, an alkyl group which may be substituted, an alkoxyl group which may be substituted, an aryl group which may be substituted, an aralkyl group which may be substituted, a carboxyl group which may be esterified or a carbamoyl group which may be substituted and m and n each are an integer from 1 to 6, and photosensitive members for electrophotography having a photosensitive layer containing them.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: May 26, 1992
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Yoshimi Kojima, Satoshi Katayama, Yoshihide Shimoda, Hiroshi Sugimura, Eiji Imada
  • Patent number: 4983741
    Abstract: 1,2,4,5-Benzoylenebis(naphtho[2,3-d]imidazole compounds of the following formula (I) or (II): ##STR1## wherein R and R' each are a hydrogen atom, a halogen atom, a hydroxyl group, a carboxyl group which may be esterified, a sulfonic acid group which may be esterified, a lower alkyl group, a lower alkenyl group, a lower alkoxy group, an aryl group which may be substituted, an aralkyl group which may be substituted, a carbamoyl group which may be substituted or a sulfamoyl group which may be substituted and m and n each are an integer of 1 or 2, and photosensitive members for electrophotography having a photosensitive layer containing these compounds.
    Type: Grant
    Filed: December 8, 1988
    Date of Patent: January 8, 1991
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Satoshi Katayama, Eiji Imada, Shuhei Tsuchimoto
  • Patent number: 4963451
    Abstract: 1,2,4,5-Benzoylenebis(anthraquinone[1,2-d]imidazole) compounds represented by following general formula (1) or (2) ##STR1## wherein R and R' each are hydrogen atom, a halogen atom, hydroxyl group, a lower alkyl group, a lower alkoxy group or an aryl group which may be substituted and m and n each are an integer of 1 or 2, and photosensitive members for electrophotography having a photosensitive layer containing them.
    Type: Grant
    Filed: September 22, 1989
    Date of Patent: October 16, 1990
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Satoshi Katayama, Yoshihide Shimoda, Hiroshi Sugimura, Eiji Imada, Shuhei Tsuchimoto
  • Patent number: 4943503
    Abstract: An amorphous silicon (a-Si) photoreceptor includes an amorphous silicon (a-Si) photoconductive layer, and a surface layer disposed above the amorphous silicon (a-Si) photoconductive layer. An intermediate layer is disposed between the amorphous-silicon (a-Si) photoconductive layer and the surface layer to ensure the energy level matching. The intermediate layer is made of amorphous silicon (a-Si) doped with nitrogen and boron so as to have the energy difference of less than 0.2 eV between the bottom of the conduction bands of the surface layer and the intermediate layer.
    Type: Grant
    Filed: October 10, 1984
    Date of Patent: July 24, 1990
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Hideo Nojima, Yoshimi Kojima, Eiji Imada, Toshiro Matsuyama, Takashi Hayakawa, Shiro Narikawa, Shaw Ehara
  • Patent number: 4908457
    Abstract: 1,2,4,5-benzoylenebis(anthraquinone[1,2-d]imidazole) compounds represented by following general formula (1) or ##STR1## wherein R and R' each are hydrogen atom, a halogen atom, hydroxyl group, a lower alkyl group, a lower alkoxy group or an aryl group which may be substituted and m and n each are an integer of 1 or 2, and photosensitive members for electrophotography having a photosensitive layer containing them.
    Type: Grant
    Filed: December 7, 1988
    Date of Patent: March 13, 1990
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Satoshi Katayama, Yoshihide Shimoda, Hiroshi Sugimura, Eiji Imada, Shuhei Tsuchimoto
  • Patent number: 4883733
    Abstract: An electrophotographic printing process is disclosed that comprises the steps of: imagewise exposing a photosensitive means with light of a wavelength at which photochromism occurs, to thereby record the image therein, wherein said photosensitive means has a photosensitive layer formed on a conductive support, said photosensitive layer containing a photochromically sensitive compound that shows photoconductivity when irradiated with light of different wavelengths before and after said photochromism occurs; charging the entire surface of said photosensitive layer; and uniformly exposing said photosensitive means with light of a wavelength at which photochromism does not occur, but at which said photochromically sensitive compound or photoisomeric compound therewith shows photoconductivity, to thereby form the image of a charge pattern on the surface of said photosensitive layer.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: November 28, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Hiroshi Sugimura, Eiji Imada, Yoshimi Kojima, Shuhei Tsuchimoto
  • Patent number: 4853309
    Abstract: A photoreceptor for electrophotography including an electrically conductive substrate, a bottom layer, a photoconductive layer composed mainly of amorphous silicon, and a surface layer, in that order. Both the bottom and surface layers have a greater optical bandgap than said photoconductive layer. A first middle layer is disposed between said bottom layer and said photoconductive layer, and a second middle layer is disposed between said photoconductive layer and said surface layer. Both the first and second middle layers are composed mainly of amorphous silicon and have a concentration of doped atoms which varies from the bottom to the top of the layer.
    Type: Grant
    Filed: June 3, 1988
    Date of Patent: August 1, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Takashi Hayakawa, Hideo Nojima, Yoshimi Kojima, Shiro Narikawa, Toshiro Matsuyama, Eiji Imada, Shaw Ehara
  • Patent number: 4687724
    Abstract: A photoreceptor for electrophotography utilizing a-Si:N:H:F, wherein a stable high-sensitive layer is provided and the time-lapse variation in characteristics is reduced in the use of an a-Si.sub.1-x N.sub.x layer as a sensitive layer.
    Type: Grant
    Filed: December 14, 1983
    Date of Patent: August 18, 1987
    Assignee: Sharp Kabushiki
    Inventors: Shaw Ehara, Yoshimi Kojima, Eiji Imada, Takashi Hayakawa, Toshiro Matsuyama
  • Patent number: 4666816
    Abstract: A method of manufacturing an electrophotographic photoreceptor having an amorphous silicon layer formed as a photoconductive layer, on an electrically conductive support member. The manufacturing method includes the steps of preparing the amorphous silicon layer as the photoconductive layer by employing Si.sub.2 H.sub.6 (disilane) as a main raw material gas through a glow discharge process, and simultaneously, adding nitrogen and boron to the main raw material gas, with the unsaturated bond being stabilized by hydrogen or hydrogen and fluorine.
    Type: Grant
    Filed: August 26, 1986
    Date of Patent: May 19, 1987
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Yoshimi Kojima, Shiro Narikawa, Takashi Hayakawa, Hideo Nojima, Eiji Imada, Toshiro Matsuyama, Shaw Ehara