Patents by Inventor Eiji Kobayashi

Eiji Kobayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10482605
    Abstract: A method comprises obtaining a first cell image of a cell by a first observation method, obtaining a second cell image of the cell by a second observation method that is different from the first observation method, and determining the region of the cell based on the first cell image and the second cell image.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: November 19, 2019
    Assignees: SYSMEX CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
    Inventors: Kazumi Hakamada, Yuki Aihara, Masaya Okada, Toshiyuki Sato, Ichiro Sekiya, Eiji Kobayashi
  • Patent number: 10389792
    Abstract: A Web browser capable of providing an equivalent quality of user experience to a user even with respect to access of devices differing in processing performance. The web browsing system comprises a Web browser function which is divided between a browsing client unit and a browsing server unit, wherein the browsing client unit notifies a content input to the user terminal to the browsing server unit and displays a Web page on a user terminal by using information supplied from the browsing server unit, and wherein the browsing server unit supplies information necessary for displaying the Web page to the user terminal to the browsing client unit according to the content input to the user terminal notified from the browsing client unit.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: August 20, 2019
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Shinichi Doi, Hiroyuki Tanaka, Eiji Kobayashi, Mika Ishizuka, Miki Kitabata, Keiichiro Kashiwagi, Ryosuke Kurebayashi
  • Patent number: 10335263
    Abstract: An organ for transplantation having a kidney, a ureter, and a urinary bladder and an organ structure in which a first ureter, a first urinary bladder, a second ureter and a second urinary bladder are sequentially connected to a kidney can produce urine and excrete the produced urine, and thus is useful for transplantation.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: July 2, 2019
    Assignee: BIOS CO., LTD.
    Inventors: Takashi Yokoo, Eiji Kobayashi, Hiroshi Nagashima, Hitomi Matsunari
  • Publication number: 20190191692
    Abstract: For perfusion, blood vessels protruding from a removed organ or tissue and cannulas for circulating perfusate are tightened and bound at positions away from the cut ends of the blood vessels toward a proximal side viewed from the organ. The cut ends of the aforementioned blood vessels that are anastomosed to blood vessels of a living body are spaced from the binding positions at which the cannulas are secured. The direction to the blood vessels of the living body can be conducted while moving the cannulas in various postures relative to the blood vessels protruding from the organ or tissue. This enables performing an anastomosis operation while maintaining the perfusion state. In this way, organs and tissues that include at least one artery route and at least one vein route can be anastomosed to blood vessels of a living body while maintaining the perfusion state.
    Type: Application
    Filed: July 31, 2017
    Publication date: June 27, 2019
    Inventors: Eiji KOBAYASHI, Takashi TSUJI, Jun ISHIKAWA, Syuhei YOSHIMOTO, Shinji TORAI
  • Publication number: 20190141988
    Abstract: A perfusion device and a perfusion method can allocate two routes of perfusate inflow pathways and two routes of perfusate outflow pathways for a liver graft. The perfusate inflow pathways have perfusate inflow cannulas connected respectively to the portal vein and the hepatic artery. The perfusate outflow pathways have perfusate outflow cannulas connected respectively to the suprahepatic inferior vena cava and the infrahepatic inferior vena cava. Perfusate is allowed to enter the liver from the perfusate inflow cannulas, and the perfusate in the liver is allowed to drain off from the perfusate outflow cannulas. This significantly shortens the time length of the liver graft being in an ischemic condition when the liver is removed or transplanted. That is, the onset of disorder in the liver graft can be suppressed. This increases the success rate of liver transplantation. Thus, deterioration of organ grafts during surgery is prevented in organ transplantation surgery that requires long hours.
    Type: Application
    Filed: May 19, 2017
    Publication date: May 16, 2019
    Inventors: Eiji KOBAYASHI, Takashi TSUJI, Jun ISHIKAWA, Soichi NADAHARA, Syuhei YOSHIMOTO, Shinji TORAI
  • Patent number: 10265346
    Abstract: A mammalian cell suspension prevents pulmonary embolism formation during administration of mammalian cells, such as mammalian stem cells, through a blood vessel, and a preventive agent against pulmonary embolism formation during administration of mammalian cells through a blood vessel. suspending mammalian cells, such as mammalian stem cells, are suspended in a physiological aqueous solution containing trehalose or its derivative, or a salt thereof as an active ingredient to prepare a mammalian cell suspension for preventing pulmonary embolism formation during administration of the mammalian cells through a blood vessel, including the mammalian cells and trehalose or its derivative, or a salt thereof as active ingredients. Examples of the mammalian cells can include pancreatic islet cells, dendritic cells, natural killer cells, alpha/beta T cells, gamma/delta T cells, and cytotoxic T lymphocytes in addition to mammalian stem cells.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: April 23, 2019
    Assignee: OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Tamaki Wada, Masako Doi, Takeshi Kikuchi, Eiji Kobayashi
  • Patent number: 10184109
    Abstract: Disclosed is a method for obtaining differentiated cells and/or differentiated cell products, including the steps of: introducing undifferentiated cells into a perfused organ or living tissue; subjecting the undifferentiated cells introduced to perfusion culture together with the organ or living tissue so as to allow the undifferentiated cells to differentiate, thereby obtaining differentiated cells and/or differentiated cell products; collecting a perfusion culture solution that contains the resulting differentiated cells and/or differentiated cell products; and obtaining the differentiated cells and/or differentiated cell products contained in the collected perfusion culture solution.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: January 22, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Eiji Kobayashi, Toshiyuki Sato, Kenji Akama, Nobuyasu Hori, Masaki Shibayama, Yuki Aihara, Masakazu Kadowaki
  • Patent number: 10087421
    Abstract: The present invention provides a mammalian stem cell suspension containing mammalian stem cells and at least one polysaccharide such as trehalose, and the like; a mammalian stem cell aggregation inhibitor containing polysaccharide such as trehalose, and the like; a method of suppressing aggregation of mammalian stem cells, containing suspending the mammalian stem cells in an aqueous physiological solution containing polysaccharide; an inhibitor of a decrease in the survival rate of mammalian stem cells containing polysaccharide such as trehalose and the like; a method of suppressing a decrease in the survival rate of mammalian stem cells, containing suspending the mammalian stem cells in an aqueous physiological solution containing polysaccharides, and the like.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: October 2, 2018
    Assignees: OTSUKA PHARMACEUTICAL FACTORY, INC., JICHI MEDICAL UNIVERSITY
    Inventors: Eiji Kobayashi, Tamaki Wada, Yasutaka Fujita, Norihiro Yoshinaga, Masako Doi, Yasuhiro Fujimoto, Takumi Teratani
  • Publication number: 20180173398
    Abstract: The point target can be easily and accurately instructed without disturbing the viewability of the point target and its neighboring display information. A touch panel type information terminal device comprises means for displaying on a display screen a touchable pointer comprising a pointer part for instructing a point target that is displayed on a display screen, and an operation part for a user to perform a touch operation, and means for integrally moving a display position of the operation part and the pointer part on the display screen in accordance with the touch operation of the user with respect to the operation part of the touchable pointer.
    Type: Application
    Filed: July 25, 2016
    Publication date: June 21, 2018
    Applicant: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Shinichi DOI, Takayuki NAKAMURA, Eiji KOBAYASHI, Hiroyuki TANAKA
  • Publication number: 20170333173
    Abstract: An organ for transplantation having a kidney, a ureter, and a urinary bladder and an organ structure in which a first ureter, a first urinary bladder, a second ureter and a second urinary bladder are sequentially connected to a kidney can produce urine and excrete the produced urine, and thus is useful for transplantation.
    Type: Application
    Filed: December 4, 2015
    Publication date: November 23, 2017
    Inventors: Takashi YOKOO, Eiji KOBAYASHI, Hiroshi NAGASHIMA, Hitomi MATSUNARI
  • Patent number: 9758766
    Abstract: The present invention provides an artificial kidney precursor containing a non-human mammalian metanephros separated out from a living body, wherein the metanephros has been subjected to freezing and thawing treatments outside a living body, and contains mammalian mesenchymal stem cells transferred outside a living body, and a method of production thereof.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: September 12, 2017
    Assignees: OTSUKA PHARMACEUTICAL FACTORY, INC., JICHI MEDICAL UNIVERSITY, THE JIKEI UNIVERSITY, TOKYO WOMEN'S MEDICAL UNIVERSITY
    Inventors: Eiji Kobayashi, Takashi Yokoo, Koutaro Kai
  • Publication number: 20170186173
    Abstract: A method comprises obtaining a first cell image of a cell by a first observation method, obtaining a second cell image of the cell by a second observation method that is different from the first observation method, and determining the region of the cell based on the first cell image and the second cell image.
    Type: Application
    Filed: December 27, 2016
    Publication date: June 29, 2017
    Inventors: Kazumi HAKAMADA, Yuki AIHARA, Masaya OKADA, Toshiyuki SATO, Ichiro SEKIYA, Eiji KOBAYASHI
  • Publication number: 20170166904
    Abstract: The purpose of the invention is to provide means with which it is possible to efficiently select a vector to which a foreign gene has been introduced when a foreign gene is to be introduced by homologous recombination to a vector having multiple sequences homologous with one another. The vector comprises, in succession, a replication origin, a sequence A, a marker gene X, two sequences C and D for introducing a foreign gene by homologous recombination, and a sequence B homologous with sequence A. The two sequences C and D are directly or indirectly adjacent to one another. The vector is used for introducing a foreign gene between the two adjacent sequences C and D.
    Type: Application
    Filed: December 7, 2016
    Publication date: June 15, 2017
    Inventors: Masae HORII, Hiroyuki KISHI, Eiji KOBAYASHI, Tatsuhiko OZAWA, Atsushi MURAGUCHI
  • Patent number: 9498500
    Abstract: Methods of washing adherent cells, capable of effectively suppressing cell death due to proteolytic enzyme treatment for detaching the adherent cell from a culture vessel and subsequent cell treatment; cell-washing solutions used for the washing method; methods of producing cell suspensions for transplantation using the cell-washing solution; and kits comprising the cell-washing solution. Trehalose or its derivative or a salt thereof is added to physiological aqueous solutions to prepare cell-washing solutions containing trehalose or its derivative or a salt thereof as an active ingredient. The cell-washing solutions can be used to wash adherent cells before detaching the adherent cells from a culture vessel by proteolytic enzyme treatment to suppress cell death due to the proteolytic enzyme treatment. The concentration of trehalose applied to the cell-washing solution may be a concentration capable of suppressing the cell death due to the proteolytic enzyme treatment, such as 0.1 to 20 (w/v) %.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: November 22, 2016
    Assignee: OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Eiji Kobayashi, Tamaki Wada, Masako Doi
  • Publication number: 20160300967
    Abstract: Provided is a photo-electric power generating device having a great fill factor.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 13, 2016
    Inventor: Eiji KOBAYASHI
  • Publication number: 20160284918
    Abstract: Provided are a photo-electric power generating element having a sufficient fill factor, and enabling a manufacturing cost to be reduced, and a manufacturing method therefor. A photo-electric power generating element 10 including: an n-type crystal semiconductor substrate 11; a p-type amorphous silicon thin film 13 overlaid on one face side of the n-type crystal semiconductor substrate 11; and an n-type amorphous silicon thin film 15 overlaid on another face side of the n-type crystal semiconductor substrate 11, in which the photo-electric power generating element 10 further includes an intrinsic amorphous silicon thin film 12 interposed between the n-type crystal semiconductor substrate 11 and the p-type amorphous silicon thin film 13, the n-type crystal semiconductor substrate 11 and the n-type amorphous silicon thin film 15 are directly bonded, and a side on which the n-type amorphous silicon thin film 15 is provided is used as a plane of light incidence.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 29, 2016
    Inventor: Eiji KOBAYASHI
  • Publication number: 20160284888
    Abstract: Provided are: a photovoltaic element that achieves an increased electrical efficiency due to having a pyramidal texture provided through etching a silicon substrate without the use of any organic solvent harmful to humans; and a manufacturing method therefor. A photovoltaic element 10 includes: a silicon substrate 11 having a pyramidal texture on the surface thereof, the pyramidal texture including a large number of pyramids and being provided through anisotropic etching; and amorphous silicon thin films 12 to 15 provided on the pyramidal texture through chemical vapor deposition, wherein the average length of diagonals of the square at base of the pyramids is adjusted to less than 5 ?m through selection of etching conditions, the average length of diagonals being defined by the following formula of: average length of diagonals=(2*“area of visual field”/“number of vertices of pyramids found in visual field”)0.5.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 29, 2016
    Inventor: Eiji KOBAYASHI
  • Publication number: 20160142466
    Abstract: A Web browser capable of providing an equivalent quality of user experience to a user even with respect to access of devices differing in processing performance. The web browsing system comprises a Web browser function which is divided between a browsing client unit and a browsing server unit, wherein the browsing client unit notifies a content input to the user terminal to the browsing server unit and displays a Web page on a user terminal by using information supplied from the browsing server unit, and wherein the browsing server unit supplies information necessary for displaying the Web page to the user terminal to the browsing client unit according to the content input to the user terminal notified from the browsing client unit.
    Type: Application
    Filed: February 10, 2014
    Publication date: May 19, 2016
    Inventors: Shinichi DOI, Hiroyuki TANAKA, Eiji KOBAYASHI, Mika ISHIZUKA, Miki KITABATA, Keiichiro KASHIWAGI, Ryosuke KUREBAYASHI
  • Patent number: 9209486
    Abstract: An all-solid-state cell contains a combination of an electrode active material and a solid electrolyte, and has a plate-shaped fired solid electrolyte body of a ceramic containing a solid electrolyte, a first electrode layer (e.g. a positive electrode) integrally formed on one surface of the fired solid electrolyte body by mixing and firing an electrode active material and a solid electrolyte, and a second electrode layer (e.g. a negative electrode) integrally formed on the other surface of the fired solid electrolyte body by mixing and firing an electrode active material and a solid electrolyte. The solid electrolyte materials added to the first electrode layer and the second electrode layer comprise an amorphous polyanion compound.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: December 8, 2015
    Assignees: Kyushu University, NGK Insulators, Ltd.
    Inventors: Shigeto Okada, Eiji Kobayashi, Kazuhiro Yamamoto, Toshihiro Yoshida, Yosuke Sato
  • Patent number: 9208037
    Abstract: The present invention provides a duplexed operation processor control system that includes operation processors, an I/O device, and at least one communication path that couples the operation processors to the I/O device, and at least one communication path that couples the operation processors with each other. The duplexed operation processor control system switches over either of the operation processors to be a primary operation processor that executes a control operation for a control target, and the other to be a secondary operation processor that is in a stand-by state, and the secondary operation processor snoops control data synchronously when the primary operation processor acquires the control data from the control target.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: December 8, 2015
    Assignees: HITACHI, LTD., HITACHI INDUSTRY & CONTROL SOLUTIONS, LTD.
    Inventors: Toshiki Shimizu, Akira Bando, Yusaku Otsuka, Yasuhiro Kiyofuji, Eiji Kobayashi, Akihiro Onozuka, Satoru Funaki, Masakazu Ishikawa, Hideaki Masuko, Yusuke Seki, Wataru Sasaki, Naoya Mashiko, Akihiro Nakano, Shin Kokura, Shoichi Ozawa, Yu Iwasaki