Abstract: An information processing device (40) according to one embodiment of the present disclosure includes: an analysis unit (41) being a first data generation unit that generates objective score data, which indicates objective scores in time series, based on a plurality of pieces of objective data regarding a patient; a processing unit (42) being a second data generation unit that generates subjective score data, which indicates subjective scores in time series, based on a plurality of pieces of subjective data obtained from the patient; and a generation unit (44) being an image generation unit that generates a score image indicating the objective score data and the subjective score data.

Abstract: An external skin treatment composition containing, based upon the total weight of the composition, 0.001% by mass or more of a diol compound of formula (I), (II), (III), or (IV) or the derivative thereof and a balance of a carrier: wherein R indicates a benzyl group or a phenyl group.

Abstract: Providing an ultraviolet absorbent or photostabilizer with excellent absorption over a wide ultraviolet wavelength range and great stability and a high safety profile, as well as an ultraviolet-absorbing composition, a photostabilized composition and an external preparation for skin, where the pyridazine derivative of the following general formula and/or a salt thereof is included as the effective component of the ultraviolet absorbent or photostabilizer, or is included in the ultraviolet-absorbing composition, the photostabilized composition and the external preparation for skin: Wherein R1, R2, R3 and R4 are not simultaneously hydrogen atom; and R2 and R3 are not simultaneously morpholino group.

Abstract: Providing an ultraviolet absorbent or photostabilizer with excellent absorption over a wide ultraviolet wavelength range and great stability and a high safety profile, as well as an ultraviolet-absorbing composition, a photostabilized composition and an external preparation for skin, where the pyridazine derivative of the following general formula and/or a salt thereof is included as the effective component of the ultraviolet absorbent or photostabilizer, or is included in the ultraviolet-absorbing composition, the photostabilized composition and the external preparation for skin: 1

Abstract: Ultraviolet absorbents and photostabilizers have an excellent absorption ability in a wide range of ultraviolet rays, and also have high stability and high safety. The ultraviolet absorbent and photostabilizer include a pyridazine derivative of the formula (1): or salts thereof. Also, described are methods for manufacturing said pyridazine derivative and/or this salts thereof comprising the process of reacting at least 10 wt % of 4,5-dichloro-3-hydroxypyridazine or 4,5-dibromo-3-hydroxypyridazine or mixtures thereof with at least 20 vol % of morpholine in reaction solution at 70° C. or higher. The ultraviolet absorbents photostabilizers include said pyridazine derivative and/or salts thereof as effective ingredient. An ultraviolet ray absorption composition and an external preparation for skin are also included.

Abstract: Ultraviolet absorbents and photostabilizers have an excellent absorption ability in a wide range of ultraviolet rays, and also have high stability and high safety. The ultraviolet absorbent and photostabilizer include a pyridazine derivative of the formula (1): or salts thereof. Also, described are methods for manufacturing said pyridazine derivative and/or this salts thereof comprising the process of reacting at least 10 wt % of 4,5-dichloro-3-hydroxypyridazine or 4,5-dibromo-3-hydroxypyridazine or mixtures thereof with at least 20 vol % of morpholine in reaction solution at 70° C. or higher. The ultraviolet absorbents photostabilizers include said pyridazine derivative and/or salts thereof as effective ingredient. An ultraviolet ray absorption composition and an external preparation for skin are also included.

Abstract: Ultraviolet absorbents and photostabilizers have an excellent absorption ability in a wide range of ultraviolet rays, and also have high stability and high safety.

Abstract: This invention provides a pharmaceutical preparation or cosmetic, and a method for effectively inhibiting the abnormal accumulation of extra-cellular matrices. In addition, a method for preventing or treating a disease resulting from the abnormal accumulation of extra-cellular matrices is also disclosed. The pharmaceutical preparation or cosmetic contains as an effective ingredient at least one substance selected from the group consisting of the extract of a plant belonging to the genus Artemisia, the genus Forsythia, the genus Sophorak the genus Pheutn the genus GI rhiza, the genus Arctium, the genus Anemarrhena, the genus Aralia, the genus Anelicia, the genus Akebia or the genus Atractylodes, the genus Akebia or the genus Atractilodes, malotilate, 2,2'-dipyridyl and o-phenanthroline.