Patents by Inventor Ekaterina M. NIKOLOVA

Ekaterina M. NIKOLOVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer
    Patent number: 11851710
    Abstract: This document provides methods and materials for identifying metastatic malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative PCR results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify metastatic malignant skin lesions are provided. This document also provides methods and materials for treating skin cancer. For example, methods and materials for identifying a mammal (e.g., a human) having a pre-metastatic skin lesion (e.g., pre-metastatic melanoma) and treating that mammal with pentamidine (4,4?-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide) are provided.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: December 26, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Alexander Meves, Ekaterina M. Nikolova
  • Methods and materials for identifying malignant skin lesions
    Patent number: 11840735
    Abstract: This document provides methods and materials for identifying malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative PCR results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify malignant skin lesions are provided.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: December 12, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Alexander Meves, Ekaterina M. Nikolova
  • METHODS AND MATERIALS FOR IDENTIFYING METASTATIC MALIGNANT SKIN LESIONS AND TREATING SKIN CANCER
    Publication number: 20200291480
    Abstract: This document provides methods and materials for identifying metastatic malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative PCR results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify metastatic malignant skin lesions are provided. This document also provides methods and materials for treating skin cancer. For example, methods and materials for identifying a mammal (e.g., a human) having a pre-metastatic skin lesion (e.g., pre-metastatic melanoma) and treating that mammal with pentamidine (4,4?-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide) are provided.
    Type: Application
    Filed: September 20, 2019
    Publication date: September 17, 2020
    Inventors: Alexander Meves, Ekaterina M. Nikolova
  • METHODS AND MATERIALS FOR IDENTIFYING MALIGNANT SKIN LESIONS
    Publication number: 20190338372
    Abstract: This document provides methods and materials for identifying malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative PCR results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify malignant skin lesions are provided.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 7, 2019
    Inventors: Alexander Meves, Ekaterina M. Nikolova
  • METHODS AND MATERIALS FOR IDENTIFYING METASTATIC MALIGNANT SKIN LESIONS AND TREATING SKIN CANCER
    Publication number: 20170275700
    Abstract: This document provides methods and materials for identifying metastatic malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative PCR results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify metastatic malignant skin lesions are provided. This document also provides methods and materials for treating skin cancer. For example, methods and materials for identifying a mammal (e.g., a human) having a pre-metastatic skin lesion (e.g., pre-metastatic melanoma) and treating that mammal with pentamidine (4,4?-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide) are provided.
    Type: Application
    Filed: August 13, 2015
    Publication date: September 28, 2017
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Alexander Meves, Ekaterina M. Nikolova
  • METHODS AND MATERIALS FOR IDENTIFYING MALIGNANT SKIN LESIONS
    Publication number: 20160222457
    Abstract: This document provides methods and materials for identifying malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative PCR results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify malignant skin lesions are provided.
    Type: Application
    Filed: August 7, 2013
    Publication date: August 4, 2016
    Inventors: Alexander MEVES, Ekaterina M. NIKOLOVA