Patents by Inventor Ekaterina V. VIAZOVKINA

Ekaterina V. VIAZOVKINA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERMOSTABLE POLYMERASE INHIBITOR COMPOSITIONS AND METHODS
    Publication number: 20220389427
    Abstract: The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.
    Type: Application
    Filed: March 4, 2022
    Publication date: December 8, 2022
    Applicant: Cepheid
    Inventors: Sergey G. Lokhov, Alexander A. Gall, Vera Baraznenok, Ekaterina V. Viazovkina, Irina Shishkina, David H. Persing
  • Thermostable polymerase inhibitor compositions and methods
    Patent number: 11299739
    Abstract: The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: April 12, 2022
    Assignee: CEPHEID
    Inventors: Sergey G. Lokhov, Alexander A. Gall, Vera Baraznenok, Ekaterina V. Viazovkina, Irina Shishkina, David H. Persing
  • THERMOSTABLE POLYMERASE INHIBITOR COMPOSITIONS AND METHODS
    Publication number: 20190316132
    Abstract: The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.
    Type: Application
    Filed: June 6, 2017
    Publication date: October 17, 2019
    Inventors: Sergey G. Lokhov, Alexander A. Gall, Vera Baraznenok, Ekaterina V. Viazovkina, Irina Shishkina, David H. Persing
  • Modified thymine polynucleotide oligomers and methods
    Patent number: 9598455
    Abstract: Disclosed are modified thymine bases that provide enhanced base-pairing affinity for adenine or 2,6-diaminopurine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified thymine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: March 21, 2017
    Assignee: Cepheid
    Inventors: Alexander A. Gall, Sergey G. Lokhov, Mikhail A. Podyminogin, Ekaterina V. Viazovkina, Kevin Patrick Lund
  • Modified cytosine polynucleotide oligomers and methods
    Patent number: 9598456
    Abstract: Disclosed are modified cytosine bases that provide enhanced base-pairing affinity for guanine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified cytosine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: March 21, 2017
    Assignee: Cepheid
    Inventors: Alexander A. Gall, Sergey G. Lokhov, Mikhail A. Podyminogin, Ekaterina V. Viazovkina, Kevin Patrick Lund
  • MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS
    Publication number: 20150275283
    Abstract: Disclosed are modified cytosine bases that provide enhanced base-pairing affinity for guanine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified cytosine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection.
    Type: Application
    Filed: March 30, 2015
    Publication date: October 1, 2015
    Inventors: Alexander A. GALL, Sergey G. Lokhov, Mikhail A. Podyminogin, Ekaterina V. Viazovkina, Kevin Patrick Lund
  • MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS
    Publication number: 20150275278
    Abstract: Disclosed are modified thymine bases that provide enhanced base-pairing affinity for adenine or 2,6-diaminopurine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified thymine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection.
    Type: Application
    Filed: March 30, 2015
    Publication date: October 1, 2015
    Inventors: Alexander A. GALL, Sergey G. LOKHOV, Mikhail A. PODYMINOGIN, Ekaterina V. VIAZOVKINA, Kevin Patrick LUND