Patents by Inventor Eku SHIMOSEGAWA

Eku SHIMOSEGAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND
    Publication number: 20230331640
    Abstract: The invention relates to a method of producing the radiolabeled aryl compound (I) Ar—X, or a salt thereof, wherein X is 211At, 210At, 123I, 124I, 125I, or 131I. The method involves reacting the aryl boronic acid compound (II) Ar—Y, or a salt thereof, wherein Y is a borono group (—B(OH)2) or an ester group thereof, with a radionuclide selected from 211At, 210At, 123I, 124I, 125I and 131I, in the presence of an oxidizing agent selected from an alkali metal iodide, an alkali metal bromide, N-bromosuccinimide, N-chlorosuccinimide and hydrogen peroxide, in water.
    Type: Application
    Filed: June 20, 2023
    Publication date: October 19, 2023
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshifumi SHIRAKAMI, Hayato IKEDA, Yasukazu KANAI, Eku SHIMOSEGAWA, Jun HATAZAWA, Tadashi WATABE, Kazuko KANEDA
  • ASTATINE SOLUTION AND METHOD FOR PRODUCING SAME
    Publication number: 20230302169
    Abstract: The invention provides a method for producing a solution containing 211At? (astatide ion) at a high radiochemical purity by using 211At obtained by a nuclear reaction as a starting material, including a step of adding a reducing agent to a solution containing an impurity derived from 211At. The invention also provides a solution containing 211At? (astatide ion) at a radiochemical purity of not less than 30%.
    Type: Application
    Filed: May 15, 2023
    Publication date: September 28, 2023
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshifumi SHIRAKAMI, Tadashi WATABE, Kazuko KANEDA, Eku SHIMOSEGAWA, Atsushi SHINOHARA, Jun HATAZAWA
  • Production method for radiolabeled aryl compound
    Patent number: 11731917
    Abstract: The invention relates to a method of producing the radiolabeled aryl compound (I) Ar—X, or a salt thereof, wherein X is 211At, 210At, 123I, 124I, 125I, or 131I. The method involves reacting the aryl boronic acid compound (II) Ar—Y, or a salt thereof, wherein Y is a borono group (—B(OH)2) or an ester group thereof, with a radionuclide selected from 211At, 210At, 123I, 124I, 125I and 131I, in the presence of an oxidizing agent selected from an alkali metal iodide, an alkali metal bromide, N-bromosuccinimide, N-chlorosuccinimide and hydrogen peroxide, in water.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: August 22, 2023
    Assignee: OSAKA UNIVERSITY
    Inventors: Yoshifumi Shirakami, Hayato Ikeda, Yasukazu Kanai, Eku Shimosegawa, Jun Hatazawa, Tadashi Watabe, Kazuko Kaneda
  • Astatine solution and method for producing same
    Patent number: 11684683
    Abstract: The invention provides a method for producing a solution containing 211At? (astatide ion) at a high radiochemical purity by using 211At obtained by a nuclear reaction as a starting material, including a step of adding a reducing agent to a solution containing an impurity derived from 211At. The invention also provides a solution containing 211At? (astatide ion) at a radiochemical purity of not less than 30%.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: June 27, 2023
    Assignee: OSAKA UNIVERSITY
    Inventors: Yoshifumi Shirakami, Tadashi Watabe, Kazuko Kaneda, Eku Shimosegawa, Atsushi Shinohara, Jun Hatazawa
  • PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND
    Publication number: 20200369578
    Abstract: The invention relates to a method of producing the radiolabeled aryl compound (I) Ar—X, or a salt thereof, wherein X is 211At, 210At, 123I, 124I, 125I, or 131I. The method involves reacting the aryl boronic acid compound (II) Ar—Y, or a salt thereof, wherein Y is a borono group (—B(OH)2) or an ester group thereof, with a radionuclide selected from 211At, 210At, 123I, 124I, 125I and 131I, in the presence of an oxidizing agent selected from an alkali metal iodide, an alkali metal bromide, N-bromosuccinimide, N-chlorosuccinimide and hydrogen peroxide, in water.
    Type: Application
    Filed: August 3, 2018
    Publication date: November 26, 2020
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshifumi SHIRAKAMI, Hayato IKEDA, Yasukazu KANAI, Eku SHIMOSEGAWA, Jun HATAZAWA, Tadashi WATABE, Kazuko KANEDA
  • ASTATINE SOLUTION AND METHOD FOR PRODUCING SAME
    Publication number: 20200360546
    Abstract: The invention provides a method for producing a solution containing 211At? (astatide ion) at a high radiochemical purity by using 211At obtained by a nuclear reaction as a starting material, including a step of adding a reducing agent to a solution containing an impurity derived from 211At. The invention also provides a solution containing 211At? (astatide ion) at a radiochemical purity of not less than 30%.
    Type: Application
    Filed: December 28, 2018
    Publication date: November 19, 2020
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshifumi SHIRAKAMI, Tadashi WATABE, Kazuko KANEDA, Eku SHIMOSEGAWA, Atsushi SHINOHARA, Jun HATAZAWA