Patents by Inventor Eleanor G. Rogan

Eleanor G. Rogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UNIFYING MECHANISM AND METHODS TO PREVENT CANCER AND NEURODEGENERATIVE DISEASES
    Publication number: 20140378522
    Abstract: The present invention relates to methods for preventing the development of cancer or neurodegenerative diseases by administering N-Acetylcysteine (NAC), melatonin, or a combination thereof. The present invention also relates to methods for diagnosing cancer and/or neurdegenerative disease by detecting or determining the amount of dopamine metabolites, 4-CE, 2-CE, methylation of CE or CE-Q conjugates.
    Type: Application
    Filed: January 13, 2014
    Publication date: December 25, 2014
    Applicant: Prevention, L.L.C.
    Inventors: Ercole L. Cavalieri, Eleanor G. Rogan
  • Unifying mechanism and methods to prevent cancer and neurodegenerative diseases
    Patent number: 8629174
    Abstract: The present invention relates to methods for preventing the development of cancer or neurodegenerative diseases by administering N-Acetylcysteine (NAC), melatonin, or a combination thereof. The present invention also relates to methods for diagnosing cancer and/or neurdegenerative disease by detecting or determining the amount of dopamine metabolites, 4-CE, 2-CE, methylation of CE or CE-Q conjugates.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: January 14, 2014
    Assignee: Prevention L.L.C.
    Inventors: Ercole L. Cavalieri, Eleanor G. Rogan
  • Biomarkers of Cancer Risk and Their Use in Cancer Detection and Prevention
    Publication number: 20080187925
    Abstract: Certain embodiments of the present invention provide methods for identifying subjects that have, or are at risk for developing, cancer and for determining the effectiveness of preventive cancer treatments.
    Type: Application
    Filed: October 30, 2007
    Publication date: August 7, 2008
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Ercole Cavalieri, Eleanor G. Rogan, Nilesh W. Gaikwad
  • Synthesis of estrogen-purine base and estrogen-mercapturate adducts and development of fluorescent probes and monoclonal antibodies to assay those adducts
    Patent number: 5952183
    Abstract: Estrogen-nucleoside, estrogen-guanine and estrogen-mercapturate adducts are potential biomarkers for determining susceptibility of animals to a number of estrogen related cancers. These adducts may be used as biomarkers for determining risk of estrogen-induced cancers. A linker chemistry has been devised to couple these adducts to protein for production of immunogens, required for production of specific monoclonal antibodies.
    Type: Grant
    Filed: April 15, 1998
    Date of Patent: September 14, 1999
    Inventors: Ercole L. Cavalieri, George P. Casale, Eleanor G. Rogan, Douglas E. Stack
  • Synthesis of estrogen-purine base and estrogen-mercapturate adducts and development of fluorescent probes and monoclonal antibodies to assay those adducts
    Patent number: 5840889
    Abstract: Estrogen-nucleoside, estrogen-guanine and estrogen-mercapturate adducts are potential biomarkers for determining susceptibility of animals to a number of estrogen related cancers. These adducts may be used as biomarkers for determining risk of estrogen-induced cancers. A linker chemistry has been devised to couple these adducts to protein for production of immunogens, required for production of specific monoclonal antibodies.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: November 24, 1998
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Ercole L. Cavalieri, George P. Casale, Eleanor G. Rogan, Douglas E. Stack