Patents by Inventor Eleftherios Mylonakis

Eleftherios Mylonakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Photolyase nucleic acids
    Patent number: 7186816
    Abstract: The invention generally provides a novel approach to identifying Enterococcal virulence factors and for identifying compounds for treating bacterial pathogenesis. The invention further provides Enterococcal virulence factors, which serve as targets for drug discovery.
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: March 6, 2007
    Assignee: The General Hospital Corporation
    Inventors: Frederick M. Ausubel, Stephen B. Calderwood, Danielle A. Garsin, Eleftherios Mylonakis, Costi D. Sifri
  • Methods of screening compounds useful for prevention of infection or pathogenicity
    Patent number: 6905670
    Abstract: Screening procedures are disclosed for identifying compounds useful for inhibiting fungal infection or pathogenicity. Methods are also disclosed for identifying fungal pathogenic virulence factors.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: June 14, 2005
    Assignee: The General Hospital Corporation
    Inventors: Frederick M. Ausubel, Stephen B. Calderwood, Eleftherios Mylonakis, Andrew Diener, Julia Plotnikova, Costi D. Sifri, Laurence G. Rahme, Man-Wah Tan, Gary B. Ruvkun, Georg Jander, Jacqueline Heard
  • Screening methods for pathogen virulence factors under low oxygen conditions
    Publication number: 20050019259
    Abstract: In general, the invention relates to screening methods for identifying pathogen virulence factors expressed under conditions of low oxygen and for identifying drugs that inhibit a pathogen. The method includes the steps of: (a) exposing a nematode to a mutagenized pathogen cultured under a low oxygen condition; (b) determining whether the mutant pathogen infects the nematode, a reduction of disease in the nematode relative to that caused by the non-mutagenized pathogen indicating a mutation in a pathogenic virulence factor; and (c) using the mutation as a marker for identifying the pathogenic virulence factor.
    Type: Application
    Filed: May 16, 2002
    Publication date: January 27, 2005
    Inventors: Frederick Ausubel, Stephen Calderwood, Eleftherios Mylonakis
  • Enterococcal virulence factors
    Publication number: 20040214208
    Abstract: The invention generally provides a novel approach to identifying Enterococcal virulence factors and for identifying compounds for treating bacterial pathogenesis. The invention further provides Enterococcal virulence factors, which serve as targets for drug discovery.
    Type: Application
    Filed: January 16, 2004
    Publication date: October 28, 2004
    Inventors: Frederick M. Ausubel, Stephen B. Calderwood, Danielle A. Garsin, Eleftherios Mylonakis, Costi D. Sifri
  • Methods of screening compounds useful for prevention of infection or pathogenicity
    Publication number: 20030086871
    Abstract: Screening procedures are disclosed for identifying compounds useful for inhibiting fungal infection or pathogenicity. Methods are also disclosed for identifying fungal pathogenic virulence factors.
    Type: Application
    Filed: May 22, 2002
    Publication date: May 8, 2003
    Inventors: Frederick M. Ausubel, Stephen B. Calderwood, Eleftherios Mylonakis, Andrew Diener, Julia Plotnikova, Costi D. Sifri, Laurence G. Rahme, Man-Wah Tan, Gary B. Ruvkun, Georg Jander, Jacqueline Heard