Patents by Inventor Elena Landi

Elena Landi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9327976
    Abstract: The present invention relates to a hydroxyapatite multi-substituted with, physiologically compatible ion species and to its biohybrid composite with a natural and/or synthetic polymer, which are useful in the preparation of a biomimetic bone substitute for treating bone tissue defects. Furthermore, the present invention relates to a method for their preparation and uses.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: May 3, 2016
    Assignees: C.N.R. CONSIGLIO NAZIONALE DELLE RICERCHE, FIN-CERAMICA FAENZA S.P.A.
    Inventors: Elena Landi, Anna Tampieri, Giancarlo Celotti, Simone Sprio, Daniele Pressato, Claudio De Luca
  • Patent number: 9327027
    Abstract: The present invention relates to hydroxyapatite doped with Fe2+ ions and Fe3+ ions which partially substitute the calcium ions in the crystal lattice. The hydroxyapatite is characterized by an intrinsic magnetism of 0.05 to 8 emu/g, measured by applying a magnetic field of 34 Oe, due to the presence of magnetic nano-domains in the crystal lattice of HA, given the limited amount of magnetic secondary phases present, less than about 3% by volume. The intrinsically magnetic hydroxyapatite can be loaded with biological substances selected in the group consisting of proteins, genes, stem cells, growth factors, vascularization factors, active substances and drugs, under the control of an external magnetic field, as a carrier and release agent for biological substances or drugs, as a contrast agent in diagnostics or for bone or osteocartilage regeneration.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: May 3, 2016
    Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, FIN-CERAMICA FAENZA S.P.A.
    Inventors: Anna Tampieri, Elena Landi, Monica Sandri, Daniele Pressato, José Rivas Rey, Manuel Banobre López, Maurilio Marcacci
  • Patent number: 9155818
    Abstract: The present invention relates to a multilayer structure (1) including a first upper layer (2) consisting of an organic matrix including collagen and at least a lower layer (3, 4, . . . 10) consisting of a composite matrix including hydroxylapatite and collagen. Furthermore, the present invention relates to a cartilaginous substitute including said multilayer structure (1) as well as an osteochondral substitute including said multilayer structure (1). Finally, the present invention relates to the use of said multilayer structure (1) for the preparation of said cartilaginous substitute and said osteochondral substitute for the treatment of cartilaginous defects and osteochondral defects or for the neo-formation of a cartilaginous tissue and/or a subchondral bone tissue.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: October 13, 2015
    Assignee: FIN-CERAMICA FAENZA S.P.A.
    Inventors: Anna Tampieri, Daniele Pressato, Claudio De Luca, Sergio Di Fede, Elena Landi
  • Publication number: 20130129634
    Abstract: The present invention relates to hydroxyapatite doped with Fe2+ ions and Fe3+ ions which partially substitute the calcium ions in the crystal lattice. The hydroxyapatite is characterized by an intrinsic magnetism of 0.05 to 8 emu/g, measured by applying a magnetic field of 34 Oe, due to the presence of magnetic nano-domains in the crystal lattice of HA, given the limited amount of magnetic secondary phases present, less than about 3% by volume. The intrinsically magnetic hydroxyapatite can be loaded with biological substances selected in the group consisting of proteins, genes, stem cells, growth factors, vascularization factors, active substances and drugs, under the control of an external magnetic field, as a carrier and release agent for biological substances or drugs, as a contrast agent in diagnostics or for bone or osteocartilage regeneration.
    Type: Application
    Filed: July 28, 2011
    Publication date: May 23, 2013
    Applicants: CONSIGLIO NAZIONALE DELLE RICERCHE, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, FIN-CERAMICA FAENZA S.P.A.
    Inventors: Anna Tampieri, Elena Landi, Monica Sandri, Daniele Pressato, José Rivas Rey, Manuel Banobre Lopez, Maurilio Marcacci
  • Publication number: 20090232875
    Abstract: The present invention relates to a multilayer structure (1) including a first upper layer (2) consisting of an organic matrix including collagen and at least a lower layer (3, 4, . . . 10) consisting of a composite matrix including hydroxylapatite and collagen. Furthermore, the present invention relates to a cartilaginous substitute including said multilayer structure (1) as well as an osteochondral substitute including said multilayer structure (1). Finally, the present invention relates to the use of said multilayer structure (1) for the preparation of said cartilaginous substitute and said osteochondral substitute for the treatment of cartilaginous defects and osteochondral defects or for the neo-formation of a cartilaginous tissue and/or a subchondral bone tissue.
    Type: Application
    Filed: March 2, 2006
    Publication date: September 17, 2009
    Applicant: FIN-CERAMICA FAENZA S.P.A.
    Inventors: Anna Tampieri, Daniele Pressato, Claudio De Luca, Sergio Di Fede, Elena Landi
  • Publication number: 20080262121
    Abstract: The present invention relates to a hydroxyapatite multi-substituted with, physiologically compatible ion species and to its biohybrid composite with a natural and/or synthetic polymer, which are useful in the preparation of a biomimetic bone substitute for treating bone tissue defects. Furthermore, the present invention relates to a method for their preparation and uses .
    Type: Application
    Filed: October 12, 2006
    Publication date: October 23, 2008
    Applicants: FIN-CERAMICA FAENZA S.P.A., C.N.R. CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Elena Landi, Anna Tampieri, Giancarlo Celotti, Simone Sprio, Daniele Pressato, Claudio De Luca