Patents by Inventor Elijah Yew

Elijah Yew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AUTOMATED TISSUE SECTION CAPTURE, INDEXING AND STORAGE SYSTEM AND METHODS
    Publication number: 20190301980
    Abstract: The present invention relates to systems and methods for transport and processing of sectioned biological samples. Preferred embodiments provide for use of a plurality of imaging and processing modalities to characterize sectioned tissue samples. Automated operation of the system provides for multimodal imaging and multistage processing to provide three-dimensional (3D) datasets for each sample.
    Type: Application
    Filed: November 17, 2017
    Publication date: October 3, 2019
    Inventors: Sean E. Anderson, Elijah Yew, Philip Knodle, Timothy Ragan
  • High sensitivity temporal focusing widefield multiphoton endoscope capable of deep imaging
    Patent number: 9867525
    Abstract: An imaging system is provided that includes a pulsed light source providing pulsed light and is applicable to both microscopes and endoscopes. One or more optical elements with certain dispersive properties are positioned to receive the pulsed light and apply selective dispersive properties to shift the focal plane according to the user and to produce two photon (2p) wide field uniform illumination and 2p wide field structured illumination for the purpose of improving the optical axial resolution and rejection of background signal. An imaging element receives the signal arising from the 2p wide field uniform illumination and 2p wide field structured illumination and produces a respective 3D resolved image of a sample.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: January 16, 2018
    Assignees: NANYANG TECHNOLOGICAL UNIVERSITY, NATIONAL UNIVERSITY OF SINGAPORE, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Yan Seng Elijah Yew, Heejin Choi, Vijay Raj Singh, Daekeun Kim, Jagath Rajapakse, Hanry Yu, Colin J. R. Sheppard, Peter T. C. So
  • MULTI-FOCI MULTIPHOTON IMAGING SYSTEMS AND METHODS
    Publication number: 20160377546
    Abstract: Multi-foci multiphoton imaging systems and methods are provided herein which advantageously implement an excitation system that avoids aberrations and a restricted field of view while utilizing a non-descanned detection system with interlaced scanning that reduces crosstalk and provides for improved imaging of tissue. The non-descanned detection system can employ a high-efficiency fiber coupled detection.
    Type: Application
    Filed: June 24, 2016
    Publication date: December 29, 2016
    Inventors: Timothy Ragan, Elijah Yew
  • HIGH SENSITIVITY TEMPORAL FOCUSING WIDEFIELD MULTIPHOTON ENDOSCOPE CAPABLE OF DEEP IMAGING
    Publication number: 20140128743
    Abstract: An imaging system is provided that includes a pulsed light source providing pulsed light and is applicable to both microscopes and endoscopes. One or more optical elements with certain dispersive properties are positioned to receive the pulsed light and apply selective dispersive properties to shift the focal plane according to the user and to produce two photon (2p) wide field uniform illumination and 2p wide field structured illumination for the purpose of improving the optical axial resolution and rejection of background signal. An imaging element receives the signal arising from the 2p wide field uniform illumination and 2p wide field structured illumination and produces a respective 3D resolved image of a sample.
    Type: Application
    Filed: April 2, 2012
    Publication date: May 8, 2014
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, NANYANG TECHNOLOGICAL UNIVERSITY, NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Yan Seng Elijah Yew, Heejin Choi, Vijay Raj Singh, Daekeun Kim, Jagath Rajapakse, Hanry Yu, Colin J.R. Sheppard, Peter T.C. So