Abstract: Disclosed is method for producing linerless non-top coated thermal printable material (300, 402). The method comprises preparing thermal printable material (200, 302) by receiving base printable material (202), wherein base printable material being 75% w/w to 85% w/w of linerless non-top coated thermal printable material; applying heat-resistant material (204) on base printable material, wherein heat-resistant material being 12% w/w to 18% w/w of linerless non-top coated thermal printable material; applying heat-sensitive material (206) on heat-resistant material to produce thermal printable material, wherein heat-sensitive material being 3% w/w to 7% w/w of linerless non-top coated thermal printable material; and subjecting thermal printable material to supercalendering operation, supercalendering operation comprising passing thermal printable material through at least two calender rolls at temperature ranging from 30° C. to 80° C.

Abstract: The invention concerns a method for inhibiting vascular endothelial growth factor receptor 2 (VEGFR2) signalling in an individual by administering an effective amount of an agent capable of activating T cell protein tyrosine phosphatase (TCPTP), and a method for inhibiting angiogenesis and treating or preventing diseases related thereto. Furthermore, this invention concerns a method for stimulating angiogenesis or for treatment or prevention of a disease benefiting from increasing the growth of blood vessels in an individual by inhibiting TCPTP.

Abstract: This invention relates to methods for activation of T cell protein tyrosine phosphatase (TCPTP) and for inhibiting tyrosine kinase signalling in an individual. The invention concerns a method for preventing or treating a disease or disorder in an individual, wherein said disease or disorder is curable by inhibiting tyrosine kinase signalling, and a method for preventing cancer, or preventing or inhibiting cancer growth, invasion or metastasis in an individual, based on activating T cell protein tyrosine phosphatase (TCPTP). The invention also concerns pharmaceutical compositions useful in the methods.

Abstract: This invention relates to methods for activation of T cell protein tyrosine phosphatase (TCPTP) and for inhibiting tyrosine kinase signalling in an individual. The invention concerns a method for preventing or treating a disease or disorder in an individual, wherein said disease or disorder is curable by inhibiting tyrosine kinase signalling, and a method for preventing cancer, or preventing or inhibiting cancer growth, invasion or metastasis in an individual, based on activating T cell protein tyrosine phosphatase (TCPTP). The invention also concerns pharmaceutical compositions useful in the methods.

Abstract: The present invention relates to a method of manufacturing heat sensitive recording material for the bar code reader wavelength range of 660–690 nm, the recording material containing a base layer and a coating, and the coating containing at least a color former and a developer. The method of the invention is characterized in that the color former and the developer are selected so that when the reflectance of the color former-developer compound on the recording material is determined, it remains below a target curve determined with a function Hp=1.775*Ap22*10?61, where Hp is the reflectance percent and Ap the wavelength (nm) used in the bar code reader.

Abstract: The present invention relates to a heat-sensitive recording material comprising a base layer and at least one coating layer, the coating layer containing the chemicals required by at least two color forming systems whereby one color forming system used is a chelate-type color forming system and the other one a compound of at least one leuco dye and at least one urea-based developer.

Abstract: The present invention relates to a method of manufacturing heat sensitive recording material for the bar code reader wavelength range of 660-690 nm, the recording material containing a base layer and a coating, and the coating containing at least a color former and a developer. The method of the invention is characterized in that the color former and the developer are selected so that when the reflectance of the color former-developer compound on the recording material is determined, it remains below a target curve determined with a function Hp=1.775*Ap22*10−61, where Hp is the reflectance percent and Ap the wavelength (nm) used in the bar code reader.