Patents by Inventor Elisa Mele

Elisa Mele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10188999
    Abstract: Globular microstructures comprising a liquid core and a solid shell that envelops the core comprising polymeric micro- or nanofibers, preferably obtained by electrospinning, comprising a hydrophobic polymer or a mixture of hydrophobic polymer with polymers derived from cellulose or with polyacrylates; the microstructures may have a further coating of nanoparticles or polymeric coating. The microstructures have applications similar to those of “liquid marbles” with improved mechanical properties.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: January 29, 2019
    Assignee: Fondazione Istituto Italiano di Technologia
    Inventors: Elisa Mele, Ilker S. Bayer, Pier Paolo Pompa, Gabriele Maiorano, Athanasia Athanasiou, Roberto Cingolani
  • Patent number: 10087311
    Abstract: Process for producing a hydrophobic composite bioelastomer, comprising a cross-linked bioelastomer matrix in which an organic phase is dispersed, comprising the reaction of cross-linking of a hydroxyl-terminated polysiloxane with a silane coupling agent, comprising an acetoxysilane, to obtain a cross-linked polysiloxane with release of acetic acid. The reaction of cross-linking is carried out in the presence of starch to cause at least partial in situ acetylation by the acetic acid released from said starch that is incorporated in the cross-linked bioelastomer matrix.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: October 2, 2018
    Assignee: FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA
    Inventors: Ilker S. Bayer, Elisa Mele, Despina Fragouli, Roberto Cingolani, Athanasia Athanasiou
  • Patent number: 10071173
    Abstract: Composition in the form of a shaped device, for use as a fiducial marker in tissues in the animal body, in radiotherapy and/or radiosurgery, characterized in that it comprises:—a core consisting of a colloidal dispersion of metal nanoparticles and/or oxides or metal salts having X-ray-contrast properties, where said nanoparticles are stabilized with surfactants, polymers or capping agents in a liquid vehicle, and—a polymeric casing that encapsulates the core, said device having a minimum size of not less than 500 microns and a maximum size not greater than 3000 microns.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: September 11, 2018
    Assignee: FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA
    Inventors: Gabriele Maiorano, Elisa Mele, Athanasia Athanasiou, Pier Paolo Pompa
  • Publication number: 20180110884
    Abstract: Composition in the form of a shaped device, for use as a fiducial marker in tissues in the animal body, in radiotherapy and/or radiosurgery, characterized in that it comprises: —a core consisting of a colloidal dispersion of metal nanoparticles and/or oxides or metal salts having X-ray-contrast properties, where said nanoparticles are stabilized with surfactants, polymers or capping agents in a liquid vehicle, and —a polymeric casing that encapsulates the core, said device having a minimum size of not less than 500 microns and a maximum size not greater than 3000 microns.
    Type: Application
    Filed: April 5, 2016
    Publication date: April 26, 2018
    Inventors: GABRIELE MAIORANO, ELISA MELE, ATHANASIA ATHANASIOU, PEIR PAOLO POMPA
  • Patent number: 9758643
    Abstract: Methods for the production of a biodegradable plastics material obtained from plant waste materials are provided which include the steps of dissolving plant waste material in an anhydrous solvent which includes anhydrous trifluoroacetic acid in order to dissolve a cellulose fraction of the material, the waste material being at least partly dehydrated in such a way that its water content is not likely to cause hydrolysis of the cellulose fraction, and removing the solvent from the solution containing the non-hydrolyzed cellulose fraction.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: September 12, 2017
    Assignee: FONDAZIONE ISTITUTO ITALIANO DI TENOLOGIA
    Inventors: Ilker S. Bayer, Elisa Mele, Despina Fragouli, Roberto Cingolani, Athanasia Athanasiou
  • Patent number: 9676914
    Abstract: Process for the production of a polymer foam with use of hydrogel pearls as porosity generating template, comprising the steps of:—providing a matrix of polymer or prepolymer in viscous state including, as a dispersed phase, hydrogel pearls, where said pearls are dispersed in said matrix so as to generate intercommunicating cells,—causing the solidification of the matrix of polymer or prepolymer to obtain said polymer foam including said hydrogel pearls, characterised in that it comprises the operation of subjecting the thus obtained foam to conditions which cause the dehydration of said hydrogel pearls so as to obtain a reduction of volume of said pearls and—removing the dehydrated pearls by immersion in water of the polymer foam or by exposure of the foam to a flow of pressurized gas or water.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: June 13, 2017
    Assignee: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
    Inventors: Despina Fragouli, Elisa Mele, Athanasia Athanasiou
  • Patent number: 9624397
    Abstract: Methods are provided for the production of poly(cyanoacrylate) micro- or nanofibers which include mixing the cyanoacrylate monomer with a dipolar aprotic solvent to form a poly(cyanoacrylate) gel, dissolving the gel in a solvent for acrylates to form a solution suitable for electrospinning, and submitting the solution thus obtained to electrospinning to form said micro- or nanofibers. The micro- or nanofibers thus obtained can be used to form coatings that adhere to a substrate as a result of thermal treatment.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: April 18, 2017
    Assignee: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
    Inventors: Ilker S. Bayer, Elisa Mele, Roberto Cingolani, Athanasia Athanasiou
  • Publication number: 20160325258
    Abstract: Globular microstructures comprising a liquid core and a solid shell that envelops the core comprising polymeric micro- or nanofibres, preferably obtained by electrospinning, comprising a hydrophobic polymer or a mixture of hydrophobic polymer with polymers derived from cellulose or with polyacrylates; the microstructures may have a further coating of nanoparticles or polymeric coating. The microstructures have applications similar to those of “liquid marbles” with improved mechanical properties.
    Type: Application
    Filed: December 16, 2014
    Publication date: November 10, 2016
    Applicant: Fondazione Istituto Italiano di Tecnologia
    Inventors: Elisa Mele, Ilker S. Bayer, Pier Paolo Pompa, Gabriele Maiorano, Athanasia Athanasiou, Roberto Cingolani
  • Publication number: 20160251501
    Abstract: Methods for the production of a biodegradable plastics material obtained from plant waste materials are provided which include the steps of dissolving plant waste material in an anhydrous solvent which includes anhydrous trifluoroacetic acid in order to dissolve a cellulose fraction of the material, the waste material being at least partly dehydrated in such a way that its water content is not likely to cause hydrolysis of the cellulose fraction, and removing the solvent from the solution containing the non-hydrolysed cellulose fraction.
    Type: Application
    Filed: October 29, 2014
    Publication date: September 1, 2016
    Applicant: FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA
    Inventors: Ilker S. BAYER, Elisa MELE, Despina FRAGOULI, Roberto CINGOLANI, Athanasia ATHANASIOU
  • Publication number: 20160160011
    Abstract: Process for producing a hydrophobic composite bioelastomer, comprising a cross-linked bioelastomer matrix in which an organic phase is dispersed, comprising the reaction of cross-linking of a hydroxyl-terminated polysiloxane with a silane coupling agent, comprising an acetoxysilane, to obtain a cross-linked polysiloxane with release of acetic acid. The reaction of cross-linking is carried out in the presence of starch to cause at least partial in situ acetylation by the acetic acid released from said starch that is incorporated in the cross-linked bioelastomer matrix.
    Type: Application
    Filed: July 7, 2014
    Publication date: June 9, 2016
    Inventors: Ilker S. BAYER, Elisa MELE, Despina FRAGOULI, Roberto CINGOLANI, Athanasia THANASIOU
  • Publication number: 20160115339
    Abstract: Methods are provided for the production of poly(cyanoacrylate) micro- or nanofibers which include mixing the cyanoacrylate monomer with a dipolar aprotic solvent to form a poly(cyanoacrylate) gel, dissolving the gel in a solvent for acrylates to form a solution suitable for electrospinning, and submitting the solution thus obtained to electrospinning to form said micro- or nanofibers. The micro- or nanofibers thus obtained can be used to form coatings that adhere to a substrate as a result of thermal treatment.
    Type: Application
    Filed: May 15, 2014
    Publication date: April 28, 2016
    Inventors: Ilker S. BAYER, Elisa MELE, Roberto CINGOLANI, Athanasia ATHANASIOU
  • Publication number: 20150315353
    Abstract: Process for the production of a polymer foam with use of hydrogel pearls as porosity generating template, comprising the steps of:—providing a matrix of polymer or prepolymer in viscous state including, as a dispersed phase, hydrogel pearls, where said pearls are dispersed in said matrix so as to generate intercommunicating cells,—causing the solidification of the matrix of polymer or prepolymer to obtain said polymer foam including said hydrogel pearls, characterised in that it comprises the operation of subjecting the thus obtained foam to conditions which cause the dehydration of said hydrogel pearls so as to obtain a reduction of volume of said pearls and—removing the dehydrated pearls by immersion in water of the polymer foam or by exposure of the foam to a flow of pressurized gas or water.
    Type: Application
    Filed: December 23, 2013
    Publication date: November 5, 2015
    Applicant: FONDAZIONE ISTITUTO ITALIANO DE TECNOLOGIA
    Inventors: Despina Fragouli, Elisa Mele, Athanasia Athanasiou