Abstract: The present disclosure relates to structured protective windows that have high transmission efficiency and can isolate light between different sections of the window. The structured protective windows are less prone to glass breakage compared to conventional protective windows that are typically used to protect and isolate light transmitting and light receiving components in LiDAR exterior automotive applications.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, CS, R2, and R3 are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, CY, Cz, R1, R2, R3, R4, R2a, Ry, Rz, and the subscripts m, n, q, and r are as described herein. The compounds or their pharmaceutically acceptable salts can inhibit the G12C mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: The present disclosure relates to light isolating arrays (can also be called “light pipes” or “light pipe arrays”) that enable high transmission efficiency and isolation of light from one location, for example a lens, to another location, for example an array of photodetector diodes (each a “PD”). The light isolating arrays can provide optical isolation of the input light and can eliminate cross talk thus enhancing the resolution via increased contrast of the incoming signal. The light isolating arrays can also protect the PD's from contamination when used in outdoor devices.