Patents by Inventor Elizabeth DUPERRET

Elizabeth DUPERRET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAGE-A vaccines and methods of treatment using the same
    Patent number: 11945851
    Abstract: Disclosed herein are compositions and methods for treating and/or preventing cancer in mammals, and in particular, vaccines that treat and provide protection against tumor growth.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: April 2, 2024
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: David Weiner, Elizabeth Duperret
  • LARGE AND SMALL T ANTIGENS OF MERKEL CELL POLYOMAVIRUS, NUCLEIC ACID CONSTRUCTS AND VACCINES MADE THEREFROM, AND METHODS OF USING SAME
    Publication number: 20230201328
    Abstract: Nucleic acid molecules and compositions comprising one or more nucleotide sequences that encode a consensus Merkel Cell Polyomavirus (MCV) T antigen. Immunomodulatory methods and methods of inducing an immune response against MCV are disclosed. Method of treating infection by MCV and methods of treating or preventing Merkel Cell Carcinoma associated with MCV are disclosed. Modified consensus MCV T antigens are disclosed.
    Type: Application
    Filed: December 12, 2022
    Publication date: June 29, 2023
    Inventors: David B. Weiner, Elizabeth Duperret
  • Large and small T antigens of merkel cell polyomavirus, nucleic acid constructs and vaccines made therefrom, and methods of using same
    Patent number: 11524065
    Abstract: Nucleic acid molecules and compositions comprising one or more nucleotide sequences that encode a consensus Merkel Cell Polyomavirus (MCV) T antigen. Immunomodulatory methods and methods of inducing an immune response against MCV are disclosed. Method of treating infection by MCV and methods of treating or preventing Merkel Cell Carcinoma associated with MCV are disclosed. Modified consensus MCV T antigens are disclosed.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: December 13, 2022
    Assignee: THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
    Inventors: David B. Weiner, Elizabeth Duperret
  • DNA-ENCODED BISPECIFIC T-CELL ENGAGERS TARGETING CANCER ANTIGENS AND METHODS OF USE IN CANCER THERAPUTICS
    Publication number: 20220098324
    Abstract: Disclosed herein are compositions comprising a recombinant nucleic acid sequence encoding a bispecific immune cell engaging antibody (DICE), a recombinant nucleic acid sequence encoding a bispecific T cell engaging (DBiTE) antibody, a fragment thereof, a variant thereof, or a combination thereof.
    Type: Application
    Filed: January 30, 2020
    Publication date: March 31, 2022
    Inventors: David Weiner, Alfredo Perales-Puchalt, Kar Muthumani, Elizabeth Duperret
  • LARGE AND SMALL T ANTIGENS OF MERKEL CELL POLYOMAVIRUS, NUCLEIC ACID CONSTRUCTS AND VACCINES MADE THEREFROM, AND METHODS OF USING SAME
    Publication number: 20200345830
    Abstract: Nucleic acid molecules and compositions comprising one or more nucleotide sequences that encode a consensus Merkel Cell Polyomavirus (MCV) T antigen. Immunomodulatory methods and methods of inducing an immune response against MCV are disclosed. Method of treating infection by MCV and methods of treating or preventing Merkel Cell Carcinoma associated with MCV are disclosed. Modified consensus MCV T antigens are disclosed.
    Type: Application
    Filed: January 18, 2019
    Publication date: November 5, 2020
    Inventors: David B. Weiner, Elizabeth Duperret
  • DNA MONOCLONAL ANTIBODIES TARGETING CTLA-4 FOR THE TREATMENT AND PREVENTION OF CANCER
    Publication number: 20200283525
    Abstract: Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody or fragment thereof that targets CTLA-4. The disclosure also provides a method of preventing and/or treating disease, such as cancer, in a subject using the composition of the invention.
    Type: Application
    Filed: October 3, 2018
    Publication date: September 10, 2020
    Inventors: David WEINER, Elizabeth DUPERRET
  • MAGE-A VACCINES AND METHODS OF TREATMENT USING THE SAME
    Publication number: 20200140508
    Abstract: Disclosed herein are compositions and methods for treating and/or preventing cancer in mammals, and in particular, vaccines that treat and provide protection against tumor growth.
    Type: Application
    Filed: June 7, 2018
    Publication date: May 7, 2020
    Inventors: David Weiner, Elizabeth Duperret
  • Optimized Synthetic Consensus Immunogenic Compositions Targeting Fibroblast Activation Protein
    Publication number: 20190328855
    Abstract: Provided herein is an immunogenic composition comprising a synthetic consensus FAP antigen. Also disclosed herein is a method of treating or preventing a tumor associated pathology in a subject in need thereof, by administering the immunogenic composition to the subject.
    Type: Application
    Filed: September 21, 2017
    Publication date: October 31, 2019
    Inventors: David WEINER, Elizabeth DUPERRET