Patents by Inventor Elizabeth G. Nabel

Elizabeth G. Nabel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
    Patent number: 5707969
    Abstract: A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems. Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This technique, provides for the transfer of cells or vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 13, 1998
    Assignee: The Regents of the University of Michigan
    Inventors: Elizabeth G. Nabel, Gary J. Nabel
  • Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
    Patent number: 5698531
    Abstract: A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems. Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This technique, provides for the transfer of cells or vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases.
    Type: Grant
    Filed: January 23, 1995
    Date of Patent: December 16, 1997
    Assignee: The Regents of the University of Michigan
    Inventors: Elizabeth G. Nabel, Gary J. Nabel
  • Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
    Patent number: 5328470
    Abstract: A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems. Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This technique, provides for the transfer of cells or vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases.
    Type: Grant
    Filed: July 26, 1991
    Date of Patent: July 12, 1994
    Assignee: The Regents of the University of Michigan
    Inventors: Elizabeth G. Nabel, Gary J. Nabel