Patents by Inventor Elizabeth J. Clarke

Elizabeth J. Clarke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20240150774
    Abstract: The disclosure relates to recombinant host cells including strain modifications effective to improve titer, yield and/or productivity of fatty acid derivatives. The disclosure further relates to cell cultures including the recombinant host cells for the fermentative production of fatty acid derivatives and compositions thereof.
    Type: Application
    Filed: June 29, 2023
    Publication date: May 9, 2024
    Inventors: Derek L. GREENFIELD, Andreas W. Schirmer, Elizabeth J. Clarke, Eli S. Groban, Bernardo M. Da Costa, Zhihao Hu, Kevin Holden, Noah Helman
  • Production Of Fatty Acid Derivatives
    Publication number: 20210348173
    Abstract: The disclosure relates to recombinant host cells including strain modifications effective to improve titer, yield and/or productivity of fatty acid derivatives. The disclosure further relates to cell cultures including the recombinant host cells for the fermentative production of fatty acid derivatives and compositions thereof.
    Type: Application
    Filed: June 1, 2021
    Publication date: November 11, 2021
    Inventors: Derek L. GREENFIELD, Andreas W. SCHIRMER, Elizabeth J. CLARKE, Eli S. GROBAN, Bernardo M. DA COSTA, Zhihao HU, Kevin HOLDEN, Noah HELMAN
  • Production of fatty acid derivatives
    Patent number: 11060099
    Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: July 13, 2021
    Assignee: Genomatica, Inc.
    Inventors: Derek L. Greenfield, Andreas W. Schirmer, Elizabeth J. Clarke, Eli S. Groban, Bernardo M. Da Costa, Zhihao Hu, Kevin Holden, Noah Helman
  • Car enzymes and improved production of fatty alcohols
    Patent number: 11034937
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: June 15, 2021
    Assignee: Genomatica, Inc.
    Inventors: Derek L. Greenfield, Elizabeth J. Clarke, Eli S. Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu, Baolong Zhu
  • NOVEL CAR ENZYMES AND IMPROVED PRODUCTION OF FATTY ALCOHOLS
    Publication number: 20200109374
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Application
    Filed: May 16, 2019
    Publication date: April 9, 2020
    Inventors: Derek L. Greenfield, Elizabeth J. Clarke, Eli S. Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu, Baolong Zhu
  • Car enzymes and improved production of fatty alcohols
    Patent number: 10301603
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: May 28, 2019
    Assignee: Reg Life Sciences, LLC
    Inventors: Derek L. Greenfield, Elizabeth J. Clarke, Eli S. Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu, Baolong Zhu
  • NOVEL CAR ENZYMES AND IMPROVED PRODUCTION OF FATTY ALCOHOLS
    Publication number: 20180135028
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Application
    Filed: September 5, 2017
    Publication date: May 17, 2018
    Inventors: Derek L. GREENFIELD, Elizabeth J. CLARKE, Eli S. GROBAN, Vikranth Arlagadda, Sungwon LEE, Xuezhi LI, Zhihao Hu, Baolong ZHU
  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20180010137
    Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
    Type: Application
    Filed: July 14, 2017
    Publication date: January 11, 2018
    Inventors: Derek L. GREENFIELD, Andreas W. Schirmer, Elizabeth J. CLARKE, Eli S. GROBAN, Bernardo M. Da Costa, Zhihao Hu, Kevin Holden, Noah Helman
  • Car enzymes and improved production of fatty alcohols
    Patent number: 9340801
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: May 17, 2016
    Assignee: REG LIFE SCIENCES, LLC
    Inventors: Derek L. Greenfield, Elizabeth J. Clarke, Eli S. Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu, Baolong Zhu
  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20150064782
    Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 5, 2015
    Applicant: REG LIFE SCIENCES, LLC
    Inventors: Derek L. Greenfield, Andreas W. Schirmer, Elizabeth J. Clarke, Eli S. Groban, Bernardo M. Da Costa, Zhihao Hu
  • NOVEL CAR ENZYMES AND IMPROVED PRODUCTION OF FATTY ALCOHOLS
    Publication number: 20150064757
    Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 5, 2015
    Applicant: REG Life Sciences, LLC
    Inventors: Derek L. Greenfield, Elizabeth J. Clarke, Eli S. Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu