Patents by Inventor Elizabeth R. Mann

Elizabeth R. Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions employing immunogenic fusion proteins
    Patent number: 11684664
    Abstract: Compositions nod methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections. Compositions provided herein comprise a variety immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing die various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or acytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: June 27, 2023
    Assignee: St. Jude Children's Research Hospital
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • METHODS AND COMPOSITIONS EMPLOYING IMMUNOGENIC FUSION PROTEINS
    Publication number: 20200246447
    Abstract: Compositions nod methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections. Compositions provided herein comprise a variety immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing die various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or acytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Application
    Filed: April 16, 2020
    Publication date: August 6, 2020
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • Methods and compositions employing immunogenic fusion proteins
    Patent number: 10632183
    Abstract: Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: April 28, 2020
    Assignee: ST. JUDE CHILDRENS RESEARCH HOSPITAL
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • METHODS AND COMPOSITIONS EMPLOYING IMMUNOGENIC FUSION PROTEINS
    Publication number: 20180078633
    Abstract: Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 22, 2018
    Applicant: St. Jude Children's Research Hospital
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • Methods and compositions employing immunogenic fusion proteins
    Patent number: 9844587
    Abstract: Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: December 19, 2017
    Assignee: St. Jude Children's Research Hospital
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • METHODS AND COMPOSITIONS EMPLOYING IMMUNOGENIC FUSION PROTEINS
    Publication number: 20160022799
    Abstract: Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumo-coccal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one poly-peptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Application
    Filed: October 7, 2015
    Publication date: January 28, 2016
    Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • Methods and compositions employing immunogenic fusion proteins
    Patent number: 9181308
    Abstract: Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumococal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: November 10, 2015
    Assignee: St. Jude Children's Research Hospital
    Inventors: Elaine Tuomanen, Elizabeth R. Mann
  • METHODS AND COMPOSITIONS EMPLOYING IMMUNOGENIC FUSION PROTEINS
    Publication number: 20140023674
    Abstract: Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumococal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.
    Type: Application
    Filed: March 23, 2012
    Publication date: January 23, 2014
    Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: Elaine Tuomanen, Elizabeth R. Mann