Abstract: Activated or partially activated zeolites can be included in analgesic balms or ointments as improved replacements for rubefacients. Upon hydration, the zeolite becomes warm, thereby helping to relieve pains associated with various musculoskeletal problems. An especially useful composition involves an ointment or balm that contains a combination of functional ingredients. A conventional analgesic such as a salicylate that can be absorbed through the skin supplies one form of relief that generally requires a period of time to become effective. When combined with the zeolite, which begins to hydrate at once, immediate relief is provided through the generated warmth.