Patents by Inventor Elmar Schrinner
Elmar Schrinner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5710146Abstract: Cephem derivatives of the general formula ##STR1## in which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.Type: GrantFiled: July 22, 1994Date of Patent: January 20, 1998Assignee: Hoechst AktiengesellschaftInventors: Walter Durckheimer, Dieter Bormann, Eberhard Ehlers, Elmar Schrinner, Rene Heymes
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Patent number: 5350753Abstract: Pharmaceutical combination preparations containing cefotaxime and at least one xanthine derivative are suitable for the treatment of bacterial infectious diseases and for the treatment of septic shock.Type: GrantFiled: June 18, 1991Date of Patent: September 27, 1994Assignee: Hoechst AktiengesellschaftInventors: Norbert Klesel, Michael Limbert, Elmar Schrinner
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Patent number: 5118500Abstract: Pharmaceuticals which contain a substance releasing tumor necrosis factor (TNF) are better tolerated and can be given in higher doses when they contain a TNF inhibitor, especially a xanthine derivative.Type: GrantFiled: May 25, 1989Date of Patent: June 2, 1992Assignee: Hoechst AktiengesellschaftInventors: Heinz Hanel, Elmar Schrinner
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Patent number: 5089490Abstract: Cephem derivatives of the general formula ##STR1## in which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.Type: GrantFiled: August 23, 1990Date of Patent: February 18, 1992Assignee: Hoechst AktiengesellschaftInventors: Walter Durckheimer, Dieter Bormann, Eberhard Ehlers, Elmar Schrinner, Rene Heymes
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Patent number: 5055457Abstract: A pharmaceutical combination product containing or composed ofa) at least one sulfated polysaccharide andb) at least one xanthine derivative.The product is suitable for controlling and preventing virus diseases, especially those caused by retroviruses.Type: GrantFiled: July 29, 1988Date of Patent: October 8, 1991Assignee: Hoechst AktiengesellschaftInventors: Elmar Schrinner, Irvin Winkler, Christoph Meichsner, Matthias Helsberg
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Patent number: 4919932Abstract: A pharmaceutical formulation having a synergistic anti-bacterial activity and comprising(a) a cephalosporin derivative or a physiologically acceptable salt or ester thereof and(b) a penem antibiotic of the basic structure (B) ##STR1## or a physiologically acceptable salt or ester thereof, a process for preparing such a formulation and its use for the treatment of bacterial infections.Type: GrantFiled: June 2, 1987Date of Patent: April 24, 1990Assignee: Hoechst AktiengesellschaftInventors: Michael Limbert, Elmar Schrinner, Gerhard Seibert
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Patent number: 4758556Abstract: Cephem derivatives of the general formula ##STR1## in which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.Type: GrantFiled: March 30, 1978Date of Patent: July 19, 1988Assignee: Hoechst AktiengesellschaftInventors: Walter Durckheimer, Dieter Bormann, Eberhard Ehlers, Elmar Schrinner, Rene Heymes
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Patent number: 4399131Abstract: What are disclosed are cephem compounds of the formula ##STR1## in which R.sub.1 denotes hydrogen, an optionally substituted alkyl, acyl, arylsulfonyl or alkylsulfonyl group or an amino-protective group which is known from peptide chemistry, R.sub.2 denotes hydrogen or an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aralkyl, acyl, aryl, arylsulfonyl, alkylsulfonyl or heterocyclic group, R.sub.3 denotes hydrogen, an ester group or a cation, R.sub.4 denotes hydrogen, a lower alkoxy group or a group which can be converted to this, X denotes a SO group in the R or S configuration or a SO.sub.2 group and A denotes hydrogen, an optionally substituted alkoxy or alkenyloxy group, halogen or a group --CH.sub.2 Y, in which Y represents hydrogen, halogen or the radical of a nucleophilic compound, and in which the R.sub.Type: GrantFiled: May 5, 1980Date of Patent: August 16, 1983Assignee: Hoechst AGInventors: Walter Durckheimer, Eberhard Ehlers, Hubert Seliger, Elmar Schrinner
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Patent number: 4293550Abstract: Cephalosporin derivatives of the formula ##STR1## processes for their manufacture and their use for combating bacterial infections.Type: GrantFiled: December 20, 1978Date of Patent: October 6, 1981Assignee: Hoechst AktiengesellschaftInventors: Jurgen Blumbach, Walter Durckheimer, Elmar Schrinner
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Patent number: 4282220Abstract: What is disclosed are cephalosporin compounds of the formula ##STR1## pharmaceutical preparations having an action against bacterial infections and containing such cephem compounds, a process for the manufacture of the cephem compounds and of pharmaceutical preparations containing the same, and the use of the cephem compounds to combat bacterial infections.Type: GrantFiled: May 24, 1979Date of Patent: August 4, 1981Assignee: Hoechst AktiengesellschaftInventors: Dieter Bormann, Walter Durckheimer, Elmar Schrinner
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Patent number: 4278793Abstract: Cephem derivatives of the general formula ##STR1## in which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.Type: GrantFiled: July 21, 1980Date of Patent: July 14, 1981Assignee: Hoechst AktiengesellschaftInventors: Walter Durckheimer, Dieter Bormann, Eberhard Ehlers, Elmar Schrinner, Rene Heymes
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Patent number: 4201779Abstract: Cephem derivatives of the formula ##STR1## in which R.sup.1 denotes hydrogen or low-molecular alkoxy, R.sup.2 denotes hydrogen, optionally substituted alkyl, phthalide or a cation, X denotes sulfur, oxygen or CH.sub.2 and A denotes hydrogen, alkoxy, halogen or a group --CH.sub.2 Y, in which Y represents hydrogen, acyloxy, alkoxy, optionally substituted carbamoyloxy or a group --SR.sup.3, in which R.sup.3 can represent acyl, alkyl or an optionally substituted 5-membered or 6-membered heterocyclic structure are disclosed as valuable antibiotics which are well suited for combating Gram-positive and in particular Gram-negative infections and also have an unexpectedly good action against penicillinase-forming staphylococci.Type: GrantFiled: March 9, 1978Date of Patent: May 6, 1980Assignee: Hoechst AktiengesellschaftInventors: Dieter Bormann, Bernd Knabe, Elmar Schrinner, Manfred Worm
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Patent number: 4035502Abstract: Acylaminopenicillanic acids of the general formula ##STR1## in which A represents phenyl which may be substituted, an aromatic monocyclic heterocycle which may be substituted or dihydrophenyl, and X represents one of the groups --SO.sub.2 --, --CO--, --P(R)-- or --P(O)(R)-- in which R represents low molecular weight alkyl, alkenyl, alkoxy, aralkyl, aralkoxy, aryl or aryloxy which may be substituted, non-toxic salts of these compounds and pharmaceutical compositions containing these compounds.Type: GrantFiled: December 3, 1975Date of Patent: July 12, 1977Assignee: Hoechst AktiengesellschaftInventors: Manfred Schorr, Elmar Schrinner, Wilfried Schmitt
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Patent number: 4018933Abstract: Acylaminopenicillanic acids of the general formula ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 represent hydrogen or lower alkyl which may be substituted, and in which the radicals R.sup.1 and R.sup.2 or R.sup.2 and R.sup.3 may form together an alkylene radical which may be substituted, R.sup.4 and R.sup.5 represent hydrogen or lower alkyl, R.sup.6 represents phenyl which may be substituted, a monocyclic aromatic heterocycle which may be substituted, or dihydrophenyl, A represents a benzene or thiophene ring which may be substituted, and X represents oxygen or a single bond, a process for preparing them and pharmaceutical compositions active against bacterial infections containing these compounds.Type: GrantFiled: December 11, 1975Date of Patent: April 19, 1977Assignee: Hoechst AktiengesellschaftInventors: Manfred Schorr, Elmar Schrinner, Wilfried Schmitt
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Patent number: 4016159Abstract: Acylamino-cephem-carboxylic acids of the formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 represent hydrogen or alkyl, R.sup.1 and R.sup.2 or R.sup.2 and R.sup.3 together may form an alkylene radical which may be substituted, X represents a single bond or NH, A represents a phenylene or thienylene radical which may be substituted, Y represents a single bond or oxygen and Z represents a 5- or 6-membered ring which may be substituted and which may be bound to an anellated ring system, and their physiologically tolerated salts and esters, a process for preparing these compounds and preparations containing them.Type: GrantFiled: November 27, 1974Date of Patent: April 5, 1977Assignee: Hoechst AktiengesellschaftInventors: Dieter Bormann, Bernd Knabe, Elmar Schrinner, Manfred Worm
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Patent number: 3993694Abstract: Antibacterially-active tetracyclines, substituted at the amide group, and physiologically-tolerable salts thereof, said tetracyclines having the formula ##SPC1##Methods of making the same; pharmaceutical compositions containing the same.Type: GrantFiled: April 11, 1975Date of Patent: November 23, 1976Assignee: Hoechst AktiengesellschaftInventors: Wolfgang Martin, Walter Durckheimer, Elmar Schrinner
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Patent number: 3983173Abstract: 2-Carboxamido-substituted tetracyclines of the general formula ##SPC1##A process for their preparation and compositions containing these compounds.Type: GrantFiled: October 31, 1974Date of Patent: September 28, 1976Assignee: Hoechst AktiengesellschaftInventors: Herbert Hartung, Walter Durckheimer, Elmar Schrinner, Hermann Gerhards
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Patent number: 3957863Abstract: New compounds of the general formula II ##EQU1## in which one or two of the radicals R.sub.i (i = 1 to 7) stands for a linear or branched alkyl or alkenyl radical of 8 to 18 carbon atoms, one or two of the radicals R.sub.m (m = 2 to 6, m being .noteq. i) stands for the radical of the formula A ##EQU2## and the other radicals R.sub.k (k = 1 to 7, k being .noteq. i, m) stand for hydrogen or methyl, Y stands for hydrogen or an alkali metal ion, n is 2 or 3 and o and p are 0 or 1, their use as anti-microbially active surfactants in washing and cleansing compositions and disinfectants, and a process for preparing those compounds of formula II.Type: GrantFiled: November 12, 1974Date of Patent: May 18, 1976Assignee: Hoechst AktiengesellschaftInventors: Helmut Diery, Elmar Schrinner, Kurd Gunther, Gerhart Schneider
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Patent number: RE35754Abstract: Cephem derivatives of the general formula ##STR1## is which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.Type: GrantFiled: July 11, 1990Date of Patent: March 24, 1998Assignee: Hoechst AktiengesellschaftInventors: Walter Durckheimer, Dieter Bormann, Eberhard Ehlers, Elmar Schrinner, Rene Heymes