Abstract: The present invention relates to the treatment of autoimmune and allergic diseases by oromucosal administration of a formulation consisting of an optimized combination of antigen, tolerizing agent and mucoadhesive carrier for each immune disease indication.

Abstract: A hydraulic manifold for a hydraulic heating and/or cooling system includes a feed conduit (212) and a return conduit (216). The feed conduit (212) includes at least one feed connection (258), and the return conduit (216) includes at least one return connection (260), for the connection of a load circuit (228). A load module (204), in which a section of the feed conduit (212) with the feed connection (258), and a section of the return conduit (216) with the return section (260) are formed, includes at least one mixing device with a pump (232) and with a regulating valve (230), to admix fluid from the return connection (260) to a fluid flow from the feed conduit (212) to the feed connection (258). The section of the feed conduit (212) and the return conduit (216) in each case include an additional contact for connection with a further load module.

Abstract: A hydraulic manifold for hydraulic heating and/or cooling systems includes a feed conduit and a return conduit. The feed conduit includes at least one feed connection and the return conduit includes at least one return connection, for the connection of a load circuit. The manifold has a modular construction with a main module and connected load module(s). The main module includes a section of the feed conduit and/or of the return conduit as well as an electric connection. The load module includes a section of the feed conduit with a feed connection, and/or a section of the return conduit with a return connection, as well as at least one regulating device for regulating the flow through a load circuit connected to the feed connection and to the return connection. The main module includes a manifold control device for the control of the regulating device in the load module(s).

Abstract: A circulation pump assembly for a heating and/or cooling system includes an electric drive motor (108) and a connected pump housing (106) in which at least one impeller (118) is situated and which comprises a first inlet (112) and a first outlet (114). The pump housing (106) includes a second inlet (122) which is connected in an inside of the pump housing (106) at a mixing point (130) to the first inlet (112). A regulating valve (134), which is designed for regulating the mixing ratio of two flows mixing at the mixing point (130), as well as a control device, which controls the regulating valve (134) for regulating the mixing ration, are arranged in the pump housing (106). A hydraulic manifold is provided with such a circulation pump assembly.

Abstract: A hydraulic manifold for a hydraulic heating and/or cooling system includes a feed conduit (212) and a return conduit (216). The feed conduit (212) includes at least one feed connection (258), and the return conduit (216) includes at least one return connection (260), for the connection of a load circuit (228). A load module (204), in which a section of the feed conduit (212) with the feed connection (258), and a section of the return conduit (216) with the return section (260) are formed, includes at least one mixing device with a pump (232) and with a regulating valve (230), to admix fluid from the return connection (260) to a fluid flow from the feed conduit (212) to the feed connection (258). The section of the feed conduit (212) and the return conduit (216) in each case include an additional contact for connection with a further load module.

Abstract: A circulation pump assembly for a heating and/or cooling system includes an electric drive motor (108) and a connected pump housing (106) in which at least one impeller (118) is situated and which comprises a first inlet (112) and a first outlet (114). The pump housing (106) includes a second inlet (122) which is connected in an inside of the pump housing (106) at a mixing point (130) to the first inlet (112). A regulating valve (134), which is designed for regulating the mixing ratio of two flows mixing at the mixing point (130), as well as a control device, which controls the regulating valve (134) for regulating the mixing ration, are arranged in the pump housing (106). A hydraulic manifold is provided with such a circulation pump assembly.

Abstract: A circulation pump assembly for a heating and/or cooling system includes an electric drive motor (108) and a connected pump housing (106) in which at least one impeller (118) is situated and which comprises a first inlet (112) and a first outlet (114). The pump housing (106) includes a second inlet (122) which is connected in an inside of the pump housing (106) at a mixing point (130) to the first inlet (112). A regulating valve (134), which is designed for regulating the mixing ratio of two flows mixing at the mixing point (130), as well as a control device, which controls the regulating valve (134) for regulating the mixing ration, are arranged in the pump housing (106). A hydraulic manifold is provided with such a circulation pump assembly.

Abstract: A hydraulic heating and/or cooling system hydraulic manifold is constructed in a modular manner with a main module (2). At least one load module (4) is connectable to the main module (2) and includes a hydraulic connection (22, 24) for a load circuit, and a closed-loop control device (26, 28) controlling flow through the load and for connection to an identically configured further load module (4). The at least one load module (4) includes a circuit board (44) which extends between a first (34) and a second axial end (36) of the load module (4) and which at its first (34) and second end (36) have electrical couplings (50, 52) which correspond to one another. The electrical coupling (52) at the second end (36) of the circuit board (44) can electrically conductively engage with an electrical coupling (50) at the first end (34) of the further identical load module (4).

Abstract: A hydraulic valve includes a valve housing (4) with an inside that defines at least one first flow path (7), and with a valve insert (16) which is arranged in the inside of the valve housing (4). The valve insert (16) includes a movable valve element (14) situated in the first flow path (7). An infrared temperature sensor (46) is arranged on or in the valve housing (4) and is directed onto a surface of the valve insert (16) or a surface of a thermal conductor (48) connected to the valve insert. A hydraulic manifold may be provided with such a hydraulic valve.

Abstract: The invention relates to a multi-stage centrifugal pump with a foot part (2), a head part (14) and a wall part (16, 16?) which connects the foot part (2) to the head part (14) and which peripherally surrounds the pump stages at the outer periphery. The centrifugal pump moreover comprises a motor stool connecting to the head part (14) and for receiving an electric motor (20) provided for the drive of the centrifugal pump. The wall part (16) projects in the axial direction beyond the head part (14) and is connected to the motor stool (FIG. 1).

Abstract: A hydraulic manifold for hydraulic heating and/or cooling systems includes a feed conduit and a return conduit. The feed conduit includes at least one feed connection and the return conduit includes at least one return connection, for the connection of a load circuit. The manifold has a modular construction with a main module and connected load module(s). The main module includes a section of the feed conduit and/or of the return conduit as well as an electric connection. The load module includes a section of the feed conduit with a feed connection, and/or a section of the return conduit with a return connection, as well as at least one regulating device for regulating the flow through a load circuit connected to the feed connection and to the return connection. The main module includes a manifold control device for the control of the regulating device in the load module(s).

Abstract: A hydraulic heating and/or cooling system hydraulic manifold is constructed in a modular manner with a main module (2). At least one load module (4) is connectable to the main module (2) and includes a hydraulic connection (22, 24) for a load circuit, and a closed-loop control device (26, 28) controlling flow through the load and for connection to an identically configured further load module (4). The at least one load module (4) includes a circuit board (44) which extends between a first (34) and a second axial end (36) of the load module (4) and which at its first (34) and second end (36) have electrical couplings (50, 52) which correspond to one another. The electrical coupling (52) at the second end (36) of the circuit board (44) can electrically conductively engage with an electrical coupling (50) at the first end (34) of the further identical load module (4).

Abstract: A hydraulic valve includes a valve housing (4) with an inside that defines at least one first flow path (7), and with a valve insert (16) which is arranged in the inside of the valve housing (4). The valve insert (16) includes a movable valve element (14) situated in the first flow path (7). An infrared temperature sensor (46) is arranged on or in the valve housing (4) and is directed onto a surface of the valve insert (16) or a surface of a thermal conductor (48) connected to the valve insert. A hydraulic manifold may be provided with such a hydraulic valve.

Abstract: A hydraulic manifold for a hydraulic heating and/or cooling system includes a feed conduit (212) and a return conduit (216). The feed conduit (212) includes at least one feed connection (258), and the return conduit (216) includes at least one return connection (260), for the connection of a load circuit (228). A load module (204), in which a section of the feed conduit (212) with the feed connection (258), and a section of the return conduit (216) with the return section (260) are formed, includes at least one mixing device with a pump (232) and with a regulating valve (230), to admix fluid from the return connection (260) to a fluid flow from the feed conduit (212) to the feed connection (258). The section of the feed conduit (212) and the return conduit (216) in each case include an additional contact for connection with a further load module.

Abstract: A circulation pump assembly for a heating and/or cooling system includes an electric drive motor (108) and a connected pump housing (106) in which at least one impeller (118) is situated and which comprises a first inlet (112) and a first outlet (114). The pump housing (106) includes a second inlet (122) which is connected in an inside of the pump housing (106) at a mixing point (130) to the first inlet (112). A regulating valve (134), which is designed for regulating the mixing ratio of two flows mixing at the mixing point (130), as well as a control device, which controls the regulating valve (134) for regulating the mixing ration, are arranged in the pump housing (106). A hydraulic manifold is provided with such a circulation pump assembly.

Abstract: A method for treating polluted material such as industrial waste water or polluted water from other sources, sewage or sewage sludge, or other forms of sludge, to degrade oxidizable substances therein. The polluted material is subjected to a wet oxidation process in a tubular reactor so as to decompose and/or modify oxidizable substances therein and improve the filterability of any solids present in the material. The material may also be pretreated to facilitate the wet oxidation process. Solid polluted material is preferably in the form of an aqueous suspension when subjected to wet oxidation. The wet oxidation process is performed to such an extent that the decomposed and/or modified substances remaining after the oxidation step are substantially biodegradable. Heavy metals may also be removed subsequent to the wet oxidation process.

Abstract: A vacuum valve for use in a tanker is constructed with means (11, 12, 13, 33, 35, 36) for applying a supplemental closing force to the valve body if the pressure drop across the vacuum valve rises substantially above a value designated for the vacuum valve. Such an extraordinary rise of the pressure drop will occur by escapage from an injury under the waterline caused by grounding, and the supplemental closing force will therefore close the valve very fast and will thereby contribute to maintaining a high vacuum in the tank, counteracting continued escape.

Abstract: A vacuum valve for use in a tanker is constructed with means for releasing a supplemental force on the valve body if the pressure drop across the vacuum valve rises substantially above a value designated for the vacuum valve. Such an extraordinary rise of the pressure drop will occur by escape from an injury under the water-line caused by grounding, and the supplemental closing froce will therefore close the valve very fast and will thereby contribute to maintaing a high vacuum in the tank, counteracting continued escape.

Abstract: A pressure relief valve for pressure equalization between a closed space and the surrounding atmosphere comprises a valve housing (1) with an upwardly facing blow-off opening (11) in which a conical valve seat (13) is formed. A drop-shaped body (14) arranged in the blow-off opening (11) is formed on its underside with a conical valve surface (15) co-operating with the valve seat (13). The drop-shaped body is connected with a lifting disc (21) which has a larger area than the valve seat (13) and is surrounded by a free passage slot (22). By suitable dimensioning, advantageous characteristics can be obtained for pressure and blow-off velocity as functions of the blow-off quantity, and the blow-off will always take place in the form of a jet which by means of the drop-shaped body (14) is directed vertically upwards at high velocity.

Abstract: A method for treating polluted material such as industrial waste water or polluted water from other sources, sewage or sewage sludge or other forms of sludge, or polluted soil, to degrade oxidizable substances therein, comprising subjecting the polluted material to a wet oxidation process in a reactor so as to decompose and/or modify oxidizable substances therein and optionally improve the filterability of solids when present in the material; the material may optionally be pretreated so as to facilitate the wet oxidation process. Solid polluted material is preferably in the form of a liquid suspension, such as an aqueous suspension, when subjected to wet oxidation. The wet oxidation process is performed to such an extent, optionally with subsequent substantial removal of heavy metals, that the decomposed and/or modified substances remaining after the wet oxidation and the optional removal of heavy metals are substantially biodegradable.