Patents by Inventor Emilian V. Racila

Emilian V. Racila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assessing response to anti-CD20 therapy by genotyping C1q components
    Patent number: 7723036
    Abstract: The present invention encompasses methods for predicting metastasis in cancer by assessing the structure of the complement protein C1qA. The methods may encompass examining either protein or nucleic acids, and may further include making treatment decisions based on the predictive methods.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: May 25, 2010
    Assignee: The University of Iowa Research Foundation
    Inventors: Emilian V. Racila, George J. Weiner
  • Methods and reagents for the rapid and efficient isolation of circulating cancer cells
    Patent number: 7332288
    Abstract: A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. In addition, the assay facilitates the biological characterization and staging of carcinoma cells.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: February 19, 2008
    Assignee: Immunivest Corporation
    Inventors: Leon W. M. M. Terstappen, Galla Chandra Rao, Jonathan W. Uhr, Emilian V. Racila, Paul A. Liberti
  • Methods and reagents for the rapid and efficient isolation of circulating cancer cells
    Patent number: 6645731
    Abstract: A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. In addition, the assay facilitates the biological characterization and staging of carcinoma cells.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: November 11, 2003
    Assignee: Immunivest Corporation
    Inventors: Leon W. M. M. Terstappen, Galla Chandra Rao, Jonathan W. Uhr, Emilian V. Racila, Paul A. Liberti
  • Methods and reagents for the rapid and efficient isolation of circulating cancer cells
    Publication number: 20030129676
    Abstract: A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. In addition, the assay facilitates the biological characterization and staging of carcinoma cells.
    Type: Application
    Filed: October 11, 2002
    Publication date: July 10, 2003
    Inventors: Leon W.M.M. Terstappen, Galla Chandra Rao, Jonathan W. Uhr, Emilian V. Racila, Paul A. Liberti
  • Methods and reagents for the rapid and efficient isolation of circulating cancer cells
    Patent number: 6365362
    Abstract: A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. In addition, the assay facilitates the biological characterization and staging of carcinoma cells.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: April 2, 2002
    Assignees: Immunivest Corporation, Board of Regents, The University of Texas System.
    Inventors: Leon W. M. M. Terstappen, Galla Chandra Rao, Jonathan W. Uhr, Emilian V. Racila, Paul A. Liberti
  • Methods and reagents for the rapid and efficient isolation of circulating cancer cells
    Publication number: 20020009759
    Abstract: A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. In addition, the assay facilitates the biological characterization and staging of carcinoma cells.
    Type: Application
    Filed: July 13, 2001
    Publication date: January 24, 2002
    Inventors: Leon W.M.M. Terstappen, Galla Chandra Rao, Jonathan W. Uhr, Emilian V. Racila, Paul A. Liberti