Patents by Inventor Emilie Porter

Emilie Porter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASES
    Publication number: 20140221336
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: February 5, 2014
    Publication date: August 7, 2014
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Marion W. Wannamaker, Francesco Salituro, Albert Pierce, Alex Aronov, Gabriel Martinez-Botella, Jian Wang, Luc Farmer, Mark Ledeboer, Tiansheng Wang, Randy Bethiel, Brian Ledford, Emilie Porter Huck
  • Beta-amino acids
    Patent number: 8772450
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: July 8, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • Compounds useful as inhibitors of Janus kinases
    Patent number: 8686143
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: April 1, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Marion W. Wannamaker, Francesco Salituro, Albert Pierce, Alex Aronov, Gabriel Martinez-Botella, Jian Wang, Luc Farmer, Mark Ledeboer, Tiansheng Wang, Randy Bethiel, Brian Ledford, Emilie Porter Huck
  • BETA-AMINO ACIDS
    Publication number: 20130023644
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: May 3, 2012
    Publication date: January 24, 2013
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • Tri-cyclic pyrazolopyridine kinase inhibitors
    Patent number: 8268999
    Abstract: The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3K?. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Grant
    Filed: August 24, 2011
    Date of Patent: September 18, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Alex Aronov, Jon H. Come, Kevin Michael Cottrell, Arnaud Le Tiran, Valerie Marone, Gabriel Martinez Botella, David Messersmith, Emilie Porter Huck, Ronald Lee Grey, Jr.
  • COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASES
    Publication number: 20120157429
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: June 21, 2012
    Inventors: Marion W. Wannamaker, Francesco Salituro, Albert Pierce, Alex Aronov, Gabriel Martinez-Botella, Jian Wang, Luc Farmer, Mark Ledeboer, Tiansheng Wang, Randy Bethiel, Brian Ledford, Emilie Porter Huck
  • Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
    Patent number: 8129424
    Abstract: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: March 6, 2012
    Assignee: Athersys, Inc.
    Inventors: Youssef L. Bennani, Michael G. Campbell, David Dastrup, Emilie Porter Huck
  • TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS
    Publication number: 20120053187
    Abstract: The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3K?. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: August 24, 2011
    Publication date: March 1, 2012
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Alex Aronov, Jon H. Come, Kevin Michael Cottrell, Arnaud Le Tiran, Valerie Marone, Gabriel Martinez Botella, David Messersmith, Emilie Porter Huck, Ronald Lee Grey, JR.
  • Pyrazoles for the treatment of obesity and other CNS disorders
    Patent number: 7981896
    Abstract: This invention relates to compounds of the formula: to compositions containing these compounds, and to methods of treatment employing the compounds and compositions.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: July 19, 2011
    Assignee: Athersys, Inc.
    Inventors: Youssef L. Bennani, Michael G. Campbell, David Dastrup, Emilie Porter Huck
  • INDOLE DERIVATIVES AS HISTAMINE 3 RECEPTOR INHIBITORS FOR THE TREATMENT OF COGNITIVE AND SLEEP DISORDERS, OBESITY AND OTHER CNS DISORDERS
    Publication number: 20110059966
    Abstract: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
    Type: Application
    Filed: November 10, 2010
    Publication date: March 10, 2011
    Inventors: Youssef L. Bennani, Michael G. Campbell, David Dastrup, Emilie Porter Huck
  • Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
    Patent number: 7855224
    Abstract: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: December 21, 2010
    Assignee: Athersys, Inc.
    Inventors: Youssef L. Bennani, Michael G. Campbell, David Dastrup, Emilie Porter Huck
  • COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASES
    Publication number: 20100160287
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: September 22, 2009
    Publication date: June 24, 2010
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Marion W. Wannamaker, Francesco Salituro, Albert Pierce, Alex Aronov, Gabriel Martinez-Botella, Jian Wang, Luc Farmer, Mark Ledeboer, Tiansheng Wang, Randy Bethiel, Brian Ledford, Emilie Porter Huck
  • Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
    Patent number: 7528262
    Abstract: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: May 5, 2009
    Assignee: Athersys, Inc.
    Inventors: Youssef L. Bennani, Michael G. Campbell, David Dastrup, Emilie Porter Huck
  • Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
    Publication number: 20090036446
    Abstract: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
    Type: Application
    Filed: September 23, 2008
    Publication date: February 5, 2009
    Inventors: Youssef L. Bennani, Michael G. Campbell, David Dastrup, Emilie Porter Huck
  • Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
    Publication number: 20070161676
    Abstract: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
    Type: Application
    Filed: October 16, 2006
    Publication date: July 12, 2007
    Inventors: Youssef Bennani, Michael Campbell, David Dastrup, Emilie Porter Huck
  • Beta-amino acids
    Publication number: 20070123709
    Abstract: Disclosed are ?-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the ? and ? carbons of the peptide backbone and ?-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the ?-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: July 7, 2006
    Publication date: May 31, 2007
    Inventors: Samuel Gellman, Daniel Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll
  • Beta-amino acids
    Publication number: 20020037997
    Abstract: Disclosed are &bgr;-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the &agr; and &bgr; carbons of the peptide backbone and &bgr;-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the &bgr;-peptide residues and libraries formed thereby are disclosed.
    Type: Application
    Filed: April 11, 2001
    Publication date: March 28, 2002
    Inventors: Samuel H. Gellman, Daniel H. Appella, Hee-Seung Lee, Paul LePlae, Emilie Porter, Xifang Wang, Matthew Woll