Patents by Inventor Emmanuelle Fantino

Emmanuelle Fantino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • hKCa3/KCNN3 small conductance calcium activated potassium channel: a diagnostic marker and therapeutic target
    Publication number: 20040137487
    Abstract: The present invention is based on the discovery and cloning of the human small conductance calcium activated potassium channel type 3 (hKCa3/KCNN3) gene, which is expressed in neuronal cells, skeletal muscle, heart, and lymphocytes. Alterations in the hKCa3/KCNN3 gene or its protein product may enhance susceptibility to schizophrenia and/or bipolar disorder. hKCa3/KCNN3 may be involved in neuropsychiatric, neurological, neuromuscular, and immunological disorders. Substantially purified hKCa3/KCNN3 polypeptides and polynucleotides are provided. Antibodies which bind to hKCa3/KCNN3 polypeptides are also disclosed. A method for identifying a compound which affects hKCa3/KCNN3 polynucleotide or polypeptide is provided. A method for diagnosis and determining the prognosis and treatment regimen of a subject having or at risk of having a hKCa3/KCNN3-associated disorder is also provided.
    Type: Application
    Filed: November 24, 2003
    Publication date: July 15, 2004
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: K. George Chandy, J. Jay Gargus, George Gutman, Emmanuelle Fantino, Katarin Kalman
  • hKCa3/KCNN3 small conductance calcium activated potassium channel: A diagnostic marker and therapeutic target
    Patent number: 6653100
    Abstract: The present invention is based on the discovery and cloning of the human small conductance calcium activated potassium channel type 3 (hKCa3/KCNN3) gene, which is expressed in neuronal cells, skeletal muscle, heart, and lymphocytes. Alterations in the hKCa3/KCNN3 gene or its protein product may enhance susceptibility to schizophrenia and/or bipolar disorder. hKCa3/KCNN3 may be involved in neuropsychiatric, neurological, neuromuscular, and immunological disorders. Substantially purified hKCa3/KCNN3 polypeptides and polynucleotides are provided. Antibodies which bind to hKCa3/KCNN3 polypeptides are also disclosed. A method for identifying a compound which affects hKCa3/KCNN3 polynucleotide or polypeptide is provided. A method for diagnosis and determining the prognosis and treatment regimen of a subject having or at risk of having a hKCa3/KCNN3-associated disorder is also provided.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: November 25, 2003
    Assignee: The Regents of the University of California
    Inventors: K. George Chandy, J. Jay Gargus, George Gutman, Emmanuelle Fantino, Katarin Kalman
  • hKCa3/KCNN3 small conductance calcium activated potassium channel: a diagnostic marker and therapeutic target
    Patent number: 6165719
    Abstract: The present invention is based on the discovery and cloning of the human small conductance calcium activated potassium channel type 3 (hKCa3/KCNN3) gene, which is expressed in neuronal cells, skeletal muscle, heart, and lymphocytes. Alterations in the hKCa3/KCNN3 gene or its protein product may enhance susceptibility to schizophrenia and/or bipolar disorder. hKCa3/KCNN3 may be involved in neuropsychiatric, neurological, neuromuscular, and immunological disorders. Substantially purified hKCa3/KNN3 polypeptides and polynucleotides are provided. Antibodies which bind to hKCa3/KCNN3 polypeptides are also disclosed. A method for identifying a compound which affects hKCa3/KCNN3 polynucleotide or polypeptide is provided. A method for diagnosis and determining the prognosis and treatment regimen of a subject having or at risk of having a hKCa3/KCNN3-associated disorder is also provided.
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: December 26, 2000
    Assignee: The Regents of the University of California
    Inventors: K. George Chandy, J. Jay Gargus, George Gutman, Emmanuelle Fantino, Katarin Kalman