Patents by Inventor Emrah Ilker OZAY

Emrah Ilker OZAY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DELIVERY OF BIOMOLECULES TO PBMCs TO MODIFY AN IMMUNE RESPONSE
    Publication number: 20240132839
    Abstract: The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.
    Type: Application
    Filed: May 16, 2023
    Publication date: April 25, 2024
    Applicant: SQZ Biotechnologies Company
    Inventors: Armon R. SHAREI, Howard BERNSTEIN, Scott LOUGHHEAD, Matthew BOOTY, Katarina BLAGOVIC, Kelan HLAVATY, Defne YARAR, Emrah Ilker OZAY, Carolyne Kelly SMITH
  • METHODS TO STIMULATE HLA-AGNOSTIC IMMUNE RESPONSES TO PROTEINS USING NUCLEATED CELLS
    Publication number: 20230263879
    Abstract: The present application provides nucleated cells comprising a protein or fragment thereof, methods of manufacturing such nucleated cells comprising the protein or fragment thereof, and methods of using such modified nucleated cells (e.g., immune cells) for stimulating an immune response in a HLA agnostic manner.
    Type: Application
    Filed: September 1, 2021
    Publication date: August 24, 2023
    Applicant: SQZ Biotechnologies Company
    Inventors: Emrah Ilker OZAY, Michael MALONEY, Scott LOUGHHEAD, Howard BERNSTEIN, Katherine SEIDL, Melissa MYINT, Armon R. SHAREI
  • Ex vivo method of generating super regulatory T cells for the prevention of autoimmune disease
    Patent number: 11702632
    Abstract: The disclosure provides an ex vivo method to prepare regulatory T cells, a population of regulatory T cells with enhanced properties and methods of using the population or complexes useful to induce Tregs in a mammal. The ex vivo methods allows for the generation and expansion of super regulatory T cells for the prevention, inhibition or treatment of autoimmune disorders.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: July 18, 2023
    Assignee: University of Massachusetts
    Inventors: Gregory N. Tew, Lisa M. Minter, Emrah Ilker Ozay
  • Delivery of biomolecules to PBMCs to modify an immune response
    Patent number: 11692168
    Abstract: The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: July 4, 2023
    Assignee: SQZ Biotechnologies Company
    Inventors: Armon R. Sharei, Howard Bernstein, Scott Loughhead, Matthew Booty, Katarina Blagovic, Kelan Hlavaty, Defne Yarar, Emrah Ilker Ozay, Carolyne Kelly Smith
  • DELIVERY OF BIOMOLECULES TO PBMCs TO MODIFY AN IMMUNE RESPONSE
    Publication number: 20200318066
    Abstract: The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.
    Type: Application
    Filed: February 27, 2020
    Publication date: October 8, 2020
    Inventors: Armon R. SHAREI, Howard BERNSTEIN, Scott LOUGHHEAD, Matthew BOOTY, Katarina BLAGOVIC, Kelan HLAVATY, Defne YARAR, Emrah Ilker OZAY, Carolyne Kelly SMITH