Patents by Inventor Enrique L. Michelotti

Enrique L. Michelotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9802936
    Abstract: This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: October 31, 2017
    Assignee: Intrexon Corporation
    Inventors: Colin M. Tice, Enrique L. Michelotti, Robert E. Hormann
  • Patent number: 8129355
    Abstract: This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: March 6, 2012
    Assignee: Intrexon Corporation
    Inventors: Colin M. Tice, Enrique L. Michelotti, Robert E. Hormann
  • Publication number: 20090111183
    Abstract: This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones.
    Type: Application
    Filed: October 9, 2007
    Publication date: April 30, 2009
    Inventors: Colin M. Tice, Enrique L. Michelotti, Robert E. Hormann
  • Publication number: 20080125465
    Abstract: This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones.
    Type: Application
    Filed: August 17, 2007
    Publication date: May 29, 2008
    Applicant: Intrexon Corporation
    Inventors: Colin M. Tice, Enrique L. Michelotti, Robert E. Hormann
  • Patent number: 7375093
    Abstract: This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: May 20, 2008
    Assignee: Intrexon Corporation
    Inventors: Colin M. Tice, Enrique L. Michelotti, Robert E. Hormann
  • Publication number: 20040049037
    Abstract: This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones.
    Type: Application
    Filed: July 3, 2003
    Publication date: March 11, 2004
    Inventors: Colin M. Tice, Enrique L. Michelotti, Robert E. Hormann
  • Patent number: 5631254
    Abstract: This invention relates to substituted dihydropyridazinones, pyridazinones and related compounds, of the formula ##STR1## wherein A, Q, D and R1 are as defined within, compositions containing these compounds and methods of controlling agricultural and mammalian fungal diseases.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 20, 1997
    Assignee: Rohm and Haas Company
    Inventors: Enrique L. Michelotti, Anne R. Egan, Ronald Ross, Jr., Willie J. Wilson
  • Patent number: 5552409
    Abstract: This invention relates to substituted dihydropyridazinones, pyridazinones and related compounds, of the formula ##STR1## wherein A, Q, D and R.sup.1 are as defined within, compositions containing these compounds and methods of controlling agricultural and mammalian fungal diseases.
    Type: Grant
    Filed: March 31, 1994
    Date of Patent: September 3, 1996
    Assignee: Rohm and Haas Company
    Inventors: Enrique L. Michelotti, Anne R. Egan, Ronald Ross, Jr., Willie J. Wilson
  • Patent number: 5346913
    Abstract: N-Iodopropargyl hydantoin compounds, methods of preparing, compositions comprising, and methods of use as antimicrobials and antifungal agents in a variety of applications.
    Type: Grant
    Filed: May 26, 1992
    Date of Patent: September 13, 1994
    Assignee: Rohm and Haas Company
    Inventors: Adam C. T. Hsu, Steven H. Shaber, Enrique L. Michelotti
  • Patent number: 5304572
    Abstract: Novel N-acetonylbenzamides and their use in controlling phytopathogenic fungi.
    Type: Grant
    Filed: December 1, 1992
    Date of Patent: April 19, 1994
    Assignee: Rohm and Haas Company
    Inventors: Enrique L. Michelotti, David H. Young
  • Patent number: 5254584
    Abstract: Certain N-acetonylbenzamides exhibit low phytotoxicity and are useful for control of a wide range of fungi, including phytopathogenic fungi of the classes Oomycetes, Ascomycetes, Deuteromycetes and Basidiomycetes.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: October 19, 1993
    Assignee: Rohm and Haas Company
    Inventors: Enrique L. Michelotti, Robert R. Raney, David H. Young
  • Patent number: 5075471
    Abstract: Insecticidal compounds of the formula ##STR1## wherein one of A or B is ferrocenyl and the other of A or B is phenyl or substituted phenyl and R is branched alkyl are effective in controlling the Southern Armyworm and Mexican Bean Beetle.
    Type: Grant
    Filed: October 9, 1990
    Date of Patent: December 24, 1991
    Assignee: Rohm and Haas Company
    Inventors: Enrique L. Michelotti, Dat P. Le, Glenn R. Carlson, Anne R. Egan