Abstract: A method can include receiving strain data associated with propagation of a hydraulic fracture in a subsurface geologic region; performing a comparison between the strain data and simulation results generated using a mesh model of the subsurface geologic region and enrichment equations that represent one or more discontinuities in the subsurface geologic region; and, based on the comparison, characterizing the subsurface geologic region.

Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: The present invention relates a method for the use of a product with propyl propane thiosulfonate (PTSO), whose purpose is the treatment and/or prophylaxis of malignant neoplasms such as solid cancers and myeloproliferative syndromes in humans. In a preferred embodiment, the method includes the selection of the PTSO compound which general formula is R-SOa-S-R, where “R” represents the n-propyl group (—CH2—CH2—CH3) and “a” is 2.

Abstract: Disinfectant and sanitizing composition comprising a mixture of 1-4% w/v of a chitin derivative, such as the biopolymer chitosan, with molecular weight between 300.000 gr/mol and 600.000 gr/mol and viscosity between 48 and 54 mPa/s, 1-3% w/w of an organic acid, 0.002-0.01% w/v of copper nanoparticles, 1-2% v/v of a vegetable essential oil, and the remainder being water. Also disclosed are a method to prepare this composition and descriptions of its use.

Abstract: A solution for handling network congestion includes: attempting, by a user equipment (UE), to initiate a data session (e.g., a voice over WiFi (VoWiFi) call) over a packet data network (PDN); receiving, by the UE, a notification of network congestion; based on at least a fast retry timer and a fast retry counter, attempting, by the UE, fast retries up to a maximum number of fast retries at a fast retry time interval; and based on at least none of the initial attempt and the fast retries initiating the data session, attempting, by the UE, slow retries at a slow retry time interval until the data session is initiated or a trigger condition halts the slow retries. In some examples, the UE receives a retry parameter set from the network including the maximum number of fast retries, the fast retry time interval, and the slow retry time interval.

Abstract: An aeronautical composite structure configured to monitor a physical status of a bonded portion between structural components using a multi-core optical fiber. A method and system for monitoring the physical status of a bonded portion in an aeronautical composite structure also uses a multi-core optical fiber. More particularly, the invention relates to a structure and method for monitoring the physical status of a bonded portion of an aeronautical composite structure from its manufacturing to its use in flight using a multi-core optical fiber.

Abstract: A solution for handling network congestion includes: attempting, by a user equipment (UE), to initiate a data session (e.g., a voice over WiFi (VoWiFi) call) over a packet data network (PDN); receiving, by the UE, a notification of network congestion; based on at least a fast retry timer and a fast retry counter, attempting, by the UE, fast retries up to a maximum number of fast retries at a fast retry time interval; and based on at least none of the initial attempt and the fast retries initiating the data session, attempting, by the UE, slow retries at a slow retry time interval until the data session is initiated or a trigger condition halts the slow retries. In some examples, the UE receives a retry parameter set from the network including the maximum number of fast retries, the fast retry time interval, and the slow retry time interval.

Abstract: An assisted and multifunctional ergonomic tricycle-type device for exercise, therapy, sports, recreation and alternative transportation for adults with or without disabilities, having a 4-piece chassis where part (1) is joined to part (2) by double equalizable hinge and the central part is “7” shaped, in the upper part of part (2) an adjustable front seat is installed, a cell phone holder and a Bluetooth speaker, and in the upper rear part of part (2) there is an equalizable arm extension housing an axle support of traction with hands and parts (2) and (3) of the chassis are joined to a support of an axle and a central shock absorber of the chassis and where part (2) also has supports on the front side of the drive axle with the feet and an adjustable support of an adjustable rear seat is installed on the upper rear part of part (3).

Abstract: The present disclosure relates generally to compositions and methods for the treatment of eye diseases (e.g., retinopathies), and more particularly, to treatment of eye diseases associated with retinal cell lipofuscin accumulation.

Abstract: An aeronautical composite structure configured to monitor a physical status of a bonded portion between structural components using a multi-core optical fiber. A method and system for monitoring the physical status of a bonded portion in an aeronautical composite structure also uses a multi-core optical fiber. More particularly, the invention relates to a structure and method for monitoring the physical status of a bonded portion of an aeronautical composite structure from its manufacturing to its use in flight using a multi-core optical fiber.

Abstract: The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy.

Abstract: The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy.

Abstract: The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy.

Abstract: A vehicle hitch cover for covering a hitch ball of a vehicle hitch is disclosed, the hitch cover including a ball cover portion for concealing the hitch ball and a secondary cover portion providing a mount for the ball cover portion. The ball cover portion includes at least one movable cover that is movable relative to the hitch ball of the vehicle hitch. The at least one movable cover is movable between a closed position for fully covering and concealing the hitch ball and an opened position for exposing the hitch ball. The secondary cover portion is in turn removably attached to the vehicle hitch.

Abstract: A method for increasing the fertilizing capacity of sperm cells, which method includes irradiating sperm cells with non-coherent red light in a discontinuous manner according to a pattern that includes at least one sequence of two irradiation periods of specific durations, which are separated by an intermediate period of darkness of a specific duration. Each of the specific periods of irradiation and darkness lasts between 8 and 15 minutes.

Abstract: Some embodiments provide a program that creates a composite media presentation from several media clips. The program creates an audition set for a particular location in a composite display area for placing media clips to specify a description of the composite media presentation. The program adds to the audition set several different types of media clips that are candidates for placement in the composite display area at the particular location. The program iteratively selects a different media clip in the audition set as the only committed media clip in the audition set to include in the composite media presentation.

Abstract: Some embodiments provide a method for a media editing application that creates a composite presentation from several different media clips. The method provides a set of editing tools for editing the composite presentation. The method provides a voice-over tool for receiving text for a voice-over that includes a transcript for a voice-over audio clip to be recorded by the media editing application as a clip of the composite presentation. The method provides a display area for scrolling the text when recording the voice-over audio clip. The display area in some embodiments is a preview display area that scrolls the text while displaying a preview of the composite presentation when recording the voice-over audio clip.

Abstract: A motor vehicle includes a steering wheel, a first touchpad integrated into the steering wheel adapted to input commands, a second touchpad integrated into the steering wheel and spatially separated from the first touchpad adapted to input commands, and a coordination module adapted to generate a command to operate a function of the motor vehicle as a function of a touch motion over the first touchpad and a simultaneously-occurring touch motion over the second touchpad.

Abstract: In a method for the operator control of a motor vehicle having a display for displaying variable information and having a microphone, the viewing direction of an operator of the motor vehicle is ascertained, it is checked whether the viewing direction of the operator is aimed toward the display, and information assigned to an acoustic command is shown on the display when a corresponding acoustic command is given while the viewing direction of the operator is aimed toward the display.