Patents by Inventor Enriqueta Coll

Enriqueta Coll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assessment of Protein C Anticoagulant Pathway By Thrombin Generation Assay In The Presence of Endothelial Cells
    Publication number: 20140080160
    Abstract: The present application discloses the effects of endothelial cell-dependent activation of the protein C anticoagulant pathway via detection of thrombin generation correlated with the activation of the protein C anticoagulant pathway in plasma in the presence of endothelial cells using a fluorogenic substrate-based thrombin generation assay.
    Type: Application
    Filed: August 12, 2013
    Publication date: March 20, 2014
    Applicant: ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
    Inventors: Enriqueta Coll, Liza Robles-Carrillo, John Francis, Ali Amirkosravi
  • Thrombin generation determination method
    Patent number: 8293493
    Abstract: A method for measuring a generation of thrombin in a sample of whole blood as a function of time includes adding to a sample of whole blood a fluorogenic substrate and a thrombin activator to form an activated sample. A conversion product is permitted to form in the activated sample. Fluorescence is measured as a function of time from a fluorescent group that is released during the formation of the conversion product with the use of a fluorescence detector. The fluorescence detector operates in an extended range mode and has an increased sensitivity. Thrombin generation as a function of time can then be calculated from the measured fluorescence as a function of time.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: October 23, 2012
    Assignee: Adventist Health System/Sunbelt, Inc.
    Inventors: Enriqueta Coll, Ali Amirkosravi, John Francis
  • Thrombin Generation Determination Method
    Publication number: 20110183365
    Abstract: A method for measuring a generation of thrombin in a sample of whole blood as a function of time includes adding to a sample of whole blood a fluorogenic substrate and a thrombin activator to form an activated sample. A conversion product is permitted to form in the activated sample. Fluorescence is measured as a function of time from a fluorescent group that is released during the formation of the conversion product with the use of a fluorescence detector. The fluorescence detector operates in an extended range mode and has an increased sensitivity. Thrombin generation as a function of time can then be calculated from the measured fluorescence as a function of time.
    Type: Application
    Filed: January 27, 2010
    Publication date: July 28, 2011
    Applicant: Adventist Health System/Sunbelt, Inc.
    Inventors: Enriqueta Coll, Ali Amirkosravi, John Francis