Patents by Inventor Eoin Coakley

Eoin Coakley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for determining hypersusceptibility of HIV-1 to non-nucleoside reverse transcriptase inhibitors
    Patent number: 10202658
    Abstract: This invention relates to methods for determining hypersusceptibility of HIV-1 viruses to non-nucleoside reverse transcriptase inhibitors (NNRTIs) based on the viral genotypes. The methods generally comprise detecting, in a gene encoding reverse transcriptase of the HIV-1, the presence of a mutation at codon 65, 69, or 74 alone or in combination with one or more mutations at certain other codons. Combinations of mutations associated with hypersusceptibility to NNRTIs are also disclosed.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: February 12, 2019
    Assignee: Monogram Biosciences, Inc.
    Inventors: Neil T. Parkin, Eoin Coakley
  • METHODS FOR TREATING LIVER TRANSPLANT RECIPIENTS
    Publication number: 20150174194
    Abstract: This application features interferon-free therapies for the prevention or treatment of HCV infection in liver transplant recipient. In one aspect, the treatment comprises administering a DAA combination to a liver transplant recipient after liver transplantation, wherein the DAA combination comprises Compound 1, ritonavir, Compound 2 and Compound 4.
    Type: Application
    Filed: December 18, 2014
    Publication date: June 25, 2015
    Applicant: ABBVIE INC.
    Inventors: Barry M. Bernstein, Eoin Coakley, Regis A. Vilchez
  • Methods and Compositions for Determining Hypersusceptibility of HIV-1 to Non-Nucleoside Reverse Transcriptase Inhibitors
    Publication number: 20120283250
    Abstract: This invention relates to methods for determining hypersusceptibility of HIV-1 viruses to non-nucleoside reverse transcriptase inhibitors (NNRTIs) based on the viral genotypes. The methods generally comprise detecting, in a gene encoding reverse transcriptase of the HIV-1, the presence of a mutation at codon 65, 69, or 74 alone or in combination with one or more mutations at certain other codons. Combinations of mutations associated with hypersusceptibility to NNRTIs are also disclosed.
    Type: Application
    Filed: May 9, 2012
    Publication date: November 8, 2012
    Applicant: Monogram Biosciences, Inc.
    Inventors: Neil T. Parkin, Eoin Coakley
  • Methods and compositions for determining hypersusceptibility of HIV-1 to non-nucleoside reverse transcriptase inhibitors
    Patent number: 8178291
    Abstract: This invention relates to methods for determining hypersusceptibility of HIV-1 viruses to non-nucleoside reverse transcriptase inhibitors (NNRTIs) based on the viral genotypes. The methods generally comprise detecting, in a gene encoding reverse transcriptase of the HIV-1, the presence of a mutation at codon 65, 69, or 74 alone or in combination with one or more mutations at certain other codons. Combinations of mutation associated with hypersusceptibility to NNRTIs are also disclosed.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: May 15, 2012
    Assignee: Monogram Biosciences, Inc.
    Inventors: Neil T. Parkin, Eoin Coakley
  • Methods and Compositions for Determining Hypersusceptibility of HIV-1 to Non-Nucleoside Reverse Transcriptase Inhibitors
    Publication number: 20090208925
    Abstract: This invention relates to methods for determining hypersusceptibility of HIV-1 viruses to non-nucleoside reverse transcriptase inhibitors (NNRTIs) based on the viral genotypes. The methods generally comprise detecting, in a gene encoding reverse transcriptase of the HIV-1, the presence of a mutation at codon 65, 69, or 74 alone or in combination with one or more mutations at certain other codons. Combinations of mutation associated with hypersusceptibility to NNRTIs are also disclosed.
    Type: Application
    Filed: February 16, 2006
    Publication date: August 20, 2009
    Inventors: Neil T. Parkin, Eoin Coakley