Patents by Inventor Eran J. Yavin

Eran J. Yavin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-inflammatory peptides derived from IL-2 and analogues thereof
    Patent number: 6906170
    Abstract: Synthetic anti-inflammatory peptides derived from the sequence of IL-2 are provided. Parent peptides of the sequences Ile-Val-Leu, Glu-Phe-Leu-Asn-Arg-Trp-Ile-Thr (SEQ ID NO:1) and Arg-Met-Leu-Thr (SEQ ID NO:2), were obtained by elastase enzymatic digestion of IL-2, synthesized and modified. The peptides are useful in conditions of acute and chronic inflammation such as in autoimmune diseases.
    Type: Grant
    Filed: August 19, 1999
    Date of Patent: June 14, 2005
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ofer Lider, Amiram Ariel, Rami Hershkoviz, Eran J. Yavin, Matityahu Fridkin
  • ANTI-INFLAMMATORY PEPTIDES DERIVED FROM C-REACTIVE PROTEIN
    Publication number: 20020119917
    Abstract: A peptide corresponding to positions 89-96 of the human C-reactive protein (CRP) of the formula: Val89-Thr-Val-Ala-Pro-Val-His-Ile96 and modifications thereof obtained by substitution, elongation, amidation of the C-terminal or acylation of the N-terminal, inhibit in vitro the enzymatic activity of human leukocyte elastase (hLE) and/or of human leukocyte cathepsin G(hCG) and can be used for the treatment of chronic inflammation conditions such as rheumatoid arthritis, pulmonary emphysema and cystic fibrosis.
    Type: Application
    Filed: January 27, 1999
    Publication date: August 29, 2002
    Inventors: MATITYAHU FRIDKIN, ERAN J. YAVIN