Abstract: A system and a method are disclosed for recommending a set of actions to be performed to improve a target performance metric of a client application. An action recommendation system receives the target performance metric from a user associated with the client application. The action recommendation system determines features of the client application describing characteristics and performance history of the client application. The features of the client application and the target performance metric is provided as input to a machine learning model that outputs sets of target features that are likely to result in improvement for the target performance metric. The action recommendation system ranks the sets of target features and selects one of the sets based on the ranking. The action recommendation system determines a set of recommended actions based on the selected set of target features and presents the set of recommended actions to the user.

Abstract: A system and a method are disclosed for recommending a set of actions to be performed to improve a target performance metric of a client application. An action recommendation system receives the target performance metric from a user associated with the client application. The action recommendation system determines features of the client application describing characteristics and performance history of the client application. The features of the client application and the target performance metric is provided as input to a machine learning model that outputs sets of target features that are likely to result in improvement for the target performance metric. The action recommendation system ranks the sets of target features and selects one of the sets based on the ranking. The action recommendation system determines a set of recommended actions based on the selected set of target features and presents the set of recommended actions to the user.

Abstract: A system and a method are disclosed for recommending a set of actions to be performed to improve a target performance metric of a client application. An action recommendation system receives the target performance metric from a user associated with the client application. The action recommendation system determines features of the client application describing characteristics and performance history of the client application. The features of the client application and the target performance metric is provided as input to a machine learning model that outputs sets of target features that are likely to result in improvement for the target performance metric. The action recommendation system ranks the sets of target features and selects one of the sets based on the ranking. The action recommendation system determines a set of recommended actions based on the selected set of target features and presents the set of recommended actions to the user.

Abstract: A system and a method are disclosed for recommending a set of actions to be performed to improve a target performance metric of a client application. An action recommendation system receives the target performance metric from a user associated with the client application. The action recommendation system determines features of the client application describing characteristics and performance history of the client application. The features of the client application and the target performance metric is provided as input to a machine learning model that outputs sets of target features that are likely to result in improvement for the target performance metric. The action recommendation system ranks the sets of target features and selects one of the sets based on the ranking. The action recommendation system determines a set of recommended actions based on the selected set of target features and presents the set of recommended actions to the user.

Abstract: A process for manufacturing a nonwoven barrier fabric having a first face and an second opposite face, with the steps of applying a primer composition by vapor or aerosol deposition, to the first face of the fabric to form a layer of the primer composition, wherein the primer composition is essentially free of fluorinated compound, and applying a barrier composition comprising at least one unsaturated fluorinated compound by vapor or aerosol deposition to the layer of primer composition to form at least one, and preferably from one (1) to four (4), more preferably two (2) or three (2), layers of the barrier composition on the layer of primer composition and a fabric obtainable according to the process.

Abstract: A process for continuous consolidation of at least one fold (22, 24), whereby the process includes unwinding a unit that consists of the at least one fold (22, 24) that is placed between two strips (26, 28) continuously along at least one curved path, the at least one fold (22, 24) being placed between guiding elements and a strip (26) to the right of the curved path to heat the at least one fold (22, 24) at least at the curved path and to exert tension on the strip (26) so that the latter compresses the at least one fold (22, 24) at least at the curved path, characterized in that it includes using strips (26, 28) whose width is greater than that of the at least one fold (22, 24) so as to be in contact on both sides of the at least one fold (22, 24).

Abstract: The object of the invention is a process for continuous consolidation of at least one fold (22, 24), whereby said process consists in unwinding a unit that consists of said at least one fold (22, 24) that is placed between two strips (26, 28) continuously along at least one curved path, said at least one fold (22, 24) being placed between guiding means and a strip (26) to the right of the curved path to heat said at least one fold (22, 24) at least at the curved path and to exert tension on said strip (26) so that the latter compresses said at least one fold (22, 24) at least at said curved path, characterized in that it consists in using strips (26, 28) whose width is greater than that of said at least one fold (22, 24) so as to be in contact on both sides of said at least one fold (22, 24).

Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, are useful as inhibitors of LFA-1/ICAM and as anti-inflammatory agents, wherein L and K are O or S; Z is N or CR4b; Ar is an optionally-substituted aryl or heteroaryl; G is a linker attached to T or M or is absent; J, M and T are selected to define a three to six membered saturated or partially unsaturated non-aromatic ring; and R2, R4a, R4b, and R4c are as defined in the specification.

Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, are useful as inhibitors of LFA-1/ICAM and as anti-inflammatory agents, wherein L and K are O or S; Z is N or CR4b; Ar is an optionally-substituted aryl or heteroaryl; G is a linker attached to T or M or is absent; J, M and T are selected to define a three to six membered saturated or partially unsaturated non-aromatic ring; and R2,R4a, R4b, and R4c are as defined in the specification.

Abstract: The present invention is directed to compounds having the formula (I): useful in treating inflammatory and immune diseases, in which K is O or S; Q is —C(?O)— or optionally substituted C1-4alkylene; Ar is optionally-substituted aryl or heteroaryl; J1, J2, J3, and Y are selected so that ring A is a five-to-six membered optionally-substituted cycloalkenyl or heterocyclo ring having 0 to 2 nitrogen heteroatoms; Z is N or C(R9); and R1, R2, R3 and R9 are as defined in the specification.

Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, 1

Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, 1

Abstract: The present invention is directed to compounds having the formula (I): 1

Abstract: Compounds having the formula (I): and pharmaceutically-acceptable salts thereof, are useful for treating inflammatory or immune diseases, in which A is a four to seven membered heterocyclic or carbocyclic saturated ring; L and K are O or S; M is N or CH; Y is N or CH; Z is hydrogen, alkyl or substituted alkyl; and R1-R4 are as defined in the specification.

Abstract: Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof, 1

Abstract: Urazole compounds having the formula (I), or pharmaceutically-acceptable salts thereof, are effective as anti-inflammatory or immunosuppressive agents, wherein L and K are O or S; Q is a linker such as —O—, —S—, C(═O), and so forth, R1 is an aryl or heteroaryl group, and R3, R4a, R4c, Z, r, s and t are as defined in the specification.

Abstract: Urazole compounds having the formula (I), 1

Abstract: Compounds having the formula (I): 1