Abstract: A cranial electrotherapy stimulation ("CES") device which generates periodic electrical signals is connected between the forehead and wrist area of a human being in order to affect electrical activity in the brain and thereby decrease the individual's craving for controlled substances such as alcohol and drugs and reduce anxiety, insomnia and depression. A portable, cranial electrical stimulator is preferably mounted adjacent the arm area or worn about the waist of a patient. A first electrode is attached to the forehead of the patient, preferably above the bridge of the nose between the eyes, and a second electrode is attached to the wrist area of one am, preferably at the radial artery. Periodic electrical pulses having a waveform with a current amplitude in the range of 0.1 to 60 mA, a voltage of approximately 40-60 volts, a frequency of approximately 0.1 to 400 Hz, and a pulse width approximately 0.

Abstract: A cranial electrotherapy stimulation ("CES") device which generates electrical pulses is applied between the forehead and wrist area of a human being in order to affect electrical activity in the brain and thereby decrease the individual's craving for controlled substances such as alcohol and drugs and reduce anxiety, insomnia and depression. A portable cranial electrical stimulator is preferably attached to the arm area or about the waist of a patient. A first electrode is attached to the forehead of the patient, preferably above the bridge of the nose between the eyes, and a second electrode is attached to the wrist area of one arm, preferably at the radial artery. Electrical pulses having an amplitude in the range of 0.1 to 1.5 mA and a frequency of approximately 100 Hz are applied for at least 20 minutes at a 20% duty cycle between the forehead and the wrist electrodes. As a result, electrical activity in the brain is affected, in particular, the amplitude of P300 electrical brain activity is increased.