Patents by Inventor Eric C. Reynolds

Eric C. Reynolds has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic peptide constructs for the diagnosis and treatment of Periodontitis associated with
    Patent number: 8431688
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: April 30, 2013
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • antigenic composition
    Patent number: 8282933
    Abstract: The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: October 9, 2012
    Assignee: CSL Limited
    Inventors: Eric C. Reynolds, Nada Slakeski, Guang Gao Chen, George Ian Barr
  • Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with
    Patent number: 7749502
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: July 6, 2010
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • Antimicrobial peptides
    Patent number: 7588752
    Abstract: The present invention provides antimicrobial peptides. The peptides are non-glycosylated, less than about 100 amino acids in length, and include an amino acid sequence selected from: AVESTVATLEA?PEVIESPPE (SEQ ID NO:3), AVESTVATLED?PEVIESPPE (SEQ ID NO:4), AVESTVATLEASPEVIESPPE (SEQ ID NO:5), AVESTVATLEDSPEVIESPPE (SEQ ID NO:6), DMPIQAFLLYQQPVLGPVR (SEQ ID NO:7), and conservative substitutions therein. These peptides can be produced synthetically; however, they can most conveniently be derived from casein.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: September 15, 2009
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Stuart G. Dashper, Neil M. O'Brien-Simpson, Gert H. Talbo, Marina Malkoski
  • Dental restorative materials
    Patent number: 7491694
    Abstract: The present invention relates to a composition for dental restoration including a dental restorative material and an effective amount of a casein phosphopeptide(CPP)-amorphous calcium phosphate (ACP) complex or casein phosphopeptide(CPP)-amorphous calcium fluoride phosphate (ACFP) complex.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: February 17, 2009
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Martin J. Tyas
  • P. gingivalis antigenic composition
    Publication number: 20080175867
    Abstract: The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
    Type: Application
    Filed: March 27, 2007
    Publication date: July 24, 2008
    Applicants: CSL Limited, The University of Melbourne
    Inventors: Eric C. Reynolds, Nada Slakeski, Chao Guang Chen, Ian George Barr
  • Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with
    Patent number: 7262271
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: August 28, 2007
    Assignees: CSL Limited, The University of Melbourne
    Inventors: Eric C. Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • Calcium phosphopeptide complexes
    Patent number: 6780844
    Abstract: Phosphopeptides containing the Ser(P) cluster sequence motif Ser(P)-Ser(P)-Ser(P)-Glu-Glu- can stabilize their own weight in amorphous calcium phosphate (ACP) and amorphous calcium fluoride phosphate (ACFP). The amorphous phases stabilized by the phosphopeptides are an excellent delivery vehicle to co-localise calcium, fluoride, and phosphate ions at the tooth surface in a slow-release amorphous form producing superior anticaries efficacy. These amorphous phases stabilized by the phosphopeptides also have utility as dietary supplements to increase calcium bioavailability and to help prevent diseases associated with calcium deficiencies.
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: August 24, 2004
    Assignee: The University of Melbourne
    Inventor: Eric C. Reynolds
  • Phosphopeptides for the treatment of dental calculus
    Patent number: 5227154
    Abstract: A method of inhibiting dental calculus by applying to the teeth an oral composition containing a dental calculus inhibiting amount of one or more of the phosphopeptides SEQ.ID NO:1 to SEQ.ID NO:9, especially in the form of a zinc/phosphopeptide complex or aggregate.
    Type: Grant
    Filed: August 22, 1991
    Date of Patent: July 13, 1993
    Assignee: The University of Melbourne
    Inventor: Eric C. Reynolds
  • Dentifrice
    Patent number: 5130123
    Abstract: A dentifrice composition useful in inhibiting caries and ginivitis comprising a caries and gingivitis inhibiting amount of a material selected from the group consisting of a water soluble salt of a whole caseinate, a water soluble salt of alpha.sub.s -caseinate, a water soluble salt of beta-casinate and a digest of a whole caseinate, alpha.sub.s -caseinate or beta-caseinate and mixtures thereof is disclosed.
    Type: Grant
    Filed: January 19, 1988
    Date of Patent: July 14, 1992
    Assignees: The University of Melbourne, The Victorian Dairy Industry Authority
    Inventors: Eric C. Reynolds, Elsdon Storey, Wallace A. McDougall
  • Anticariogenic phosphopeptides
    Patent number: 5015628
    Abstract: A phosphopeptide or a salt thereof the phosphopeptide having from 5 to 30 amino acids including the sequenceA-B-C-D-Ewhere A, B, C, D and E are independently phosphoserine, phosphothreonine, phosphotyrosine, phosphohistidine, glutamate and aspartate and compositions particularly compositions to teeth including same.
    Type: Grant
    Filed: August 3, 1990
    Date of Patent: May 14, 1991
    Assignees: The University of Melbourne, Victorian Dairy Industry Authority
    Inventor: Eric C. Reynolds