Patents by Inventor Eric Defranc

Eric Defranc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prefunctionalized nucleotide and process for amplifying a sequence using a prefunctionalized nucleotide
    Patent number: 6537783
    Abstract: A target nucleic acid sequence amplification method wherein at least the target nucleic acid sequence, at least one oligonucleotide primer specific for the target sequence, one or more enzymatic activities and nucleotides are provided, and the target sequence is amplified under conditions suitable in particular for said enzymatic or activity or activities, is disclosed. According to the method, at least one of the nucleotides is a prefunctionalized nucleotide that differs from the other nucleotides at least in that it includes at least one unprotected reactive covalence function in at least one predetermined site of the base of said nucleotide, in order to give a prefunctionalized amplificati product including at least one such prefunctionalized nucleotide. Nucleotides for carrying out the method are also disclosed.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: March 25, 2003
    Assignee: Bio Merieux
    Inventors: Françoise Guillou-Bonnici, Eric Defranc, Antoine Hoang, Ali Laayoun, Jean Lhomme, Emmanuelle Trevisiol