Patents by Inventor Eric Grouzmann

Eric Grouzmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONICAL MULTI-WELL FILTER PLATE
    Publication number: 20150238956
    Abstract: The present invention relates to a multi-well filter plate able to facilitate, simplify and accelerate preparation and treatment of samples to be analyzed by for example liquid chromatography tandem mass spectrometry (UPLC—MS/MS method for simultaneous quantification of analytes).
    Type: Application
    Filed: September 11, 2013
    Publication date: August 27, 2015
    Applicant: CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
    Inventors: Eric Grouzmann, Marielle Dunand, Danilo Gubian
  • SYNERGIC ACTION OF A PROLYL PROTEASE AND TRIPEPTIDYL PROTEASES
    Publication number: 20120276075
    Abstract: The present invention relates to a novel enzyme composition comprising a prolyl protease and tripeptidyl proteases having unique catalytic properties. The present invention further relates to methods for producing the enzyme composition as well as a pharmaceutical composition and a food supplement containing the enzyme composition and its use in the degradation of polypeptides.
    Type: Application
    Filed: December 20, 2010
    Publication date: November 1, 2012
    Applicant: CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
    Inventors: Michel Monod, Eric Grouzmann
  • Fungal dipeptidyl peptidase IV (DPPIV) enzyme for reagent use
    Patent number: 7943340
    Abstract: Disclosed herein are fungal nucleic acid sequences that encode novel dipetidyl peptidase IV (DPPIV) polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The aminopeptidase polypeptides, referred to herein as DPPIV proteins of the invention are useful in a variety of medical, research, and commercial applications.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: May 17, 2011
    Assignee: Funzyme Biotechnologies SA
    Inventors: Michel Monod, Reto Stocklin, Eric Grouzmann
  • Novel fungal proteins and nucleic acids encoding same
    Publication number: 20090130737
    Abstract: Disclosed herein are fungal nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The novel leucine aminopeptidase (LAP) and other amino- and carboxypeptidases polypeptides, referred to herein as EXOX nucleic acids and proteins of the invention are useful in a variety of medical, research, and commercial applications.
    Type: Application
    Filed: July 3, 2008
    Publication date: May 21, 2009
    Applicant: Funzyme Biotechnologies SA
    Inventors: Michel Monod, Reto Stocklin, Eric Grouzmann
  • Fungal proteins and nucleic acids encoding same
    Patent number: 7468267
    Abstract: Disclosed herein are fungal nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The novel leucine aminopeptidase (LAP) and other amino- and carboxypeptidases polypeptides, referred to herein as EXOX nucleic acids and proteins of the invention are useful in a variety of medical, research, and commercial applications.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: December 23, 2008
    Assignee: Funzyme Biotechnologies SA
    Inventors: Michel Monod, Reto Stocklin, Eric Grouzmann
  • Fungal proteins and nucleic acids encoding same
    Patent number: 7354734
    Abstract: Disclosed herein are fungal nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The novel leucine aminopeptidase (LAP) and other amino- and carboxypeptidases polypeptides, referred to herein as EXOX nucleic acids and proteins of the invention are useful in a variety of medical, research, and commercial applications.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: April 8, 2008
    Assignee: Funzyme Biotechnologies SA
    Inventors: Michel Monod, Reto Stocklin, Eric Grouzmann
  • Novel fungal proteins and nucleic acids encoding same
    Publication number: 20070009988
    Abstract: Disclosed herein are fungal nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The novel leucine aminopeptidase (LAP) and other amino- and carboxypeptidases polypeptides, referred to herein as EXOX nucleic acids and proteins of the invention are useful in a variety of medical, research, and commercial applications.
    Type: Application
    Filed: August 25, 2004
    Publication date: January 11, 2007
    Applicant: FUNZYME BIOTECHNOLOGIES SA
    Inventors: Michel Monod, Reto Stocklin, Eric Grouzmann
  • Novel fungal proteins and nucleic acids encoding same
    Publication number: 20050158298
    Abstract: Disclosed herein are fungal nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The novel leucine aminopeptidase (LAP) and other amino- and carboxypeptidases polypeptides, referred to herein as EXOX nucleic acids and proteins of the invention are useful in a variety of medical, research, and commercial applications.
    Type: Application
    Filed: August 25, 2004
    Publication date: July 21, 2005
    Inventors: Michel Monod, Reto Stocklin, Eric Grouzmann
  • Treatment of substance P-related disorders
    Patent number: 6709651
    Abstract: The present invention is directed to methods of treating a wide variety of diseases, disorders and conditions characterized by excessive activity of substance P. The treatment involves administering peptidases that recognize and selectively cleave polypeptides at Xaa-Pro sequences.
    Type: Grant
    Filed: July 3, 2001
    Date of Patent: March 23, 2004
    Assignee: B.M.R.A. Corporation B.V.
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Template associated NPY Y2-receptor agonists
    Publication number: 20040009905
    Abstract: The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
    Type: Application
    Filed: June 18, 2003
    Publication date: January 15, 2004
    Applicant: B.M.R.A. Corporation B.V.
    Inventors: Manfred Mutter, Jean-Silvain Lacroix, Eric Grouzmann
  • Method of treating rhinitis or sinusitis
    Publication number: 20030165489
    Abstract: The present invention is directed to methods of treating mucosal inflammation associated with rhinitis or sinusitis by administering peptidases that recognize and cleave polypeptides at Xaa-Pro sequences. In addition, the invention encompasses therapeutic packages in which pharmaceutical compositions containing the peptidases are preloaded in a device suitable for intranasally delivering drug.
    Type: Application
    Filed: November 27, 2001
    Publication date: September 4, 2003
    Applicant: B.M.R.A. Corporation B.V.
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Treatment of substance P-related disorders
    Publication number: 20030007965
    Abstract: The present invention is directed to methods of treating a wide variety of diseases, disorders and conditions characterized by excessive activity of substance P. The treatment involves administering peptidases that recognize and selectively cleave polypeptides at Xaa-Pro sequences.
    Type: Application
    Filed: July 3, 2001
    Publication date: January 9, 2003
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Method of treating rhinitis or sinusitis by intranasally administering a peptidase
    Patent number: 6337069
    Abstract: The present invention is directed to methods of treating mucosal inflammation associated with rhinitis or sinusitis by administering peptidases that recognize and cleave polypeptides at Xaa-Pro sequences. In addition, the invention encompasses therapeutic packages in which pharmaceutical compositions containing the peptidases are preloaded in a device suitable for intranasally delivering drug.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: January 8, 2002
    Assignee: B.M.R.A. Corporation B.V.
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Template associated NPY Y2-receptor agonists
    Patent number: 6288029
    Abstract: The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: September 11, 2001
    Inventors: Manfred Mutter, Jean-Silvain Lacroix, Eric Grouzmann
  • Template associated NPY Y2-receptor agonists
    Patent number: 6017879
    Abstract: The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: January 25, 2000
    Assignee: B.M.R.A. Corporation B.V.
    Inventors: Manfred Mutter, Jean-Silvain Lacroix, Eric Grouzmann