Patents by Inventor Eric Jon Jacobsen

Eric Jon Jacobsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6492385
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: December 10, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Substituted indolines
    Publication number: 20020160999
    Abstract: The present invention provides pharmaceutically active compounds of formula I as described herein useful for the treatment of diseases or disorders of the central nervous system.
    Type: Application
    Filed: December 28, 2001
    Publication date: October 31, 2002
    Inventors: Susan Fox Jacobsen, Kalpana M. Merchant, Eric Jon Jacobsen
  • 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
    Publication number: 20020156275
    Abstract: The present invention are substituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (X) and unsubstituted 9-arylsulfone- 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (XI) such as the compound of EXAMPLE 13 1
    Type: Application
    Filed: October 30, 2001
    Publication date: October 24, 2002
    Applicant: Pharmacia and Upjohn Company
    Inventors: Eric Jon Jacobsen, Susan Fox Jacobsen
  • 1,2,3,4,5,6,-hexahydroazepino [4,5-b]indoles containing arylsulfones at the 9-position
    Patent number: 6468999
    Abstract: The present invention are substituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (X) and unsubstituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (XI) such as the compound of EXAMPLE 13 which are useful in treating depression, obesity and other CNS disorders.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: October 22, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Eric Jon Jacobsen, Susan Korynne Hendges
  • 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
    Publication number: 20020128475
    Abstract: The present invention are substituted 9-arylsulfone- 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles (X) and unsubstituted 9-arylsulfone- 1,2,3,4,5,6- hexahydroazepino[4,5-b]indoles (XI) such as the compound of EXAMPLE 13 which are useful in treating depression, obesity and other CNS disorders.
    Type: Application
    Filed: October 30, 2001
    Publication date: September 12, 2002
    Applicant: Pharmacia & Upjohn Company
    Inventors: Eric Jon Jacobsen, Susan Fax Jacobsen
  • Bis -arylsulfones
    Publication number: 20020115660
    Abstract: The present invention provides pharmaceutically active compounds useful for the treatment of diseases or disorders of the central nervous system.
    Type: Application
    Filed: October 2, 2001
    Publication date: August 22, 2002
    Inventors: Eric Jon Jacobsen, Stephen J. King, Kalpana M. Merchant
  • 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
    Publication number: 20020111483
    Abstract: The present invention are substituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (X) and unsubstituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (XI) such as the compound of EXAMPLE 13 1
    Type: Application
    Filed: October 30, 2001
    Publication date: August 15, 2002
    Applicant: Pharmacia & Upjohn Company
    Inventors: Eric Jon Jacobsen, Susan Fox Jacobsen
  • Substituted azepino[4,5b]indole derivatives
    Publication number: 20020107278
    Abstract: Disclosed are compounds of Formula (I): 1
    Type: Application
    Filed: September 20, 2001
    Publication date: August 8, 2002
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier, Eric Jon Jacobsen
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020091135
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: July 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi,, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Substituted azepino[4,5b] indoline derivatives
    Publication number: 20020077318
    Abstract: The invention provides compounds of Formula (I): 1
    Type: Application
    Filed: September 20, 2001
    Publication date: June 20, 2002
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, Eric Jon Jacobsen, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier
  • Tetracyclic azepinoindole compounds
    Patent number: 6407092
    Abstract: The present invention provides compounds of formula I: wherein R1, R2, X and Y have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of formula (I).
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: June 18, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jackson B. Hester, Bruce N. Rogers, Eric Jon Jacobsen, Michael D. Ennis, Brad A. Acker, Susan L. Vander Velde, Kristine E. Frank
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020042428
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: April 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi,, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020042429
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: April 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Bis-arylsulfones
    Publication number: 20020037892
    Abstract: The present invention provides pharmaceutically active compounds useful for the treatment of diseases or disorders of the central nervous system.
    Type: Application
    Filed: June 8, 2001
    Publication date: March 28, 2002
    Inventors: Eric Jon Jacobsen, Stephen J. King
  • Bis-sulfonamides hydroxamic acids as MMP inhibitors
    Patent number: 5859061
    Abstract: The present invention provides a compound of formula I ##STR1## or pharmaceutically acceptable salts thereof wherein R.sup.1 and R.sup.2 are the same or different and are C.sub.1-10 alkyl, phenyl, hetero-aryl, or phenyl substituted with C.sub.1-4 alkyl, OR.sup.3, NHR.sup.3, CONHR.sup.3, NHCOR.sup.3, or halo; wherein R.sup.3 is H, or C.sub.1-4 alkyl; and n is 1, 2, 3, 4, 5, or 6. The compounds are inhibitors of matrix metalloproteinases involved in tissue degradation.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: January 12, 1999
    Assignee: Pharmacia & Upjohn Company
    Inventors: Eric Jon Jacobsen, Louis L. Skaletzky
  • .alpha.-Amino sulfonyl hydroxamic acids as matrix metalloproteinase inhibitors
    Patent number: 5804593
    Abstract: A compound of formula I or pharmaceutical acceptable salts thereof, ##STR1## wherein R.sub.1 is isopropyl, 2-methylbut-2yl, phenyl, benzyl, or 1H-indol-3ylmethyl; R.sub.2 is n-octyl, phenyl, or phenyl substituted with methoxy, fluoro, or bromo, are matrix metalloproteinase inhibitors.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: September 8, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Martha A. Warpehoski, Mark Allen Mitchell, Eric Jon Jacobsen
  • Imidazo?1,5-a!quinolines for treatment of anxiety and sleep disorders
    Patent number: RE35840
    Abstract: The present invention is to imidazo?1,5-a!quinolines (I) which are useful pharmaceutical agents for the treatment of anxiety, sleep disorders, panic states, convulsions and muscle disorders.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: July 7, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Eric Jon Jacobsen, Ruth Elizabeth TenBrink