Patents by Inventor Eric Manas

Eric Manas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (Hydroxyphenyl)-1H-Indole-3-Carbaldehyde Oxime Derivatives As Estrogenic Agents
    Publication number: 20070249703
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure where R1, R2, R3, and R4 are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 20, 2007
    Publication date: October 25, 2007
    Applicant: Wyeth
    Inventors: Richard Mewshaw, Stephen Bowen, Eric Manas
  • 2-Amino-5-piperidinylimidazolone compounds and use thereof for beta-secretase modulation
    Publication number: 20070191431
    Abstract: The present invention provides a 2-amino-5-piperidinylimidazolone compound of formula I The present invention also provides methods and compositions for the inhibition of ?-secretase (BACE) and the treatment of ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: December 18, 2006
    Publication date: August 16, 2007
    Applicant: Wyeth
    Inventors: Ping Zhou, Ronald Bernotas, Yanfang Li, Pawel Nowak, Derek Cole, Eric Manas, Yi Fan, Yinfa Yan
  • Substituted benzoxazoles as estrogenic agents
    Publication number: 20070167503
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R1, R2, R2a, R3, R3a, and R4, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 11, 2006
    Publication date: July 19, 2007
    Applicant: Wyeth
    Inventors: Michael Malamas, Robert McDevitt, Iwan Gunawan, Eric Manas, Michael Collini, Heather Harris, James Keith, Leo Albert, C. Richard Lyttle
  • Azolylacylguanidines as beta-secretase inhibitors
    Publication number: 20060183790
    Abstract: The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: February 13, 2006
    Publication date: August 17, 2006
    Applicant: Wyeth
    Inventors: Derek Cole, Eric Manas, Lee Jennings, Frank Lovering, Joseph Stock, William Moore, John Ellingboe, Jeffrey Condon, Mohani Sukhdeo, Ping Zhou, JunJun Wu, Koi Morris
  • Estrogen receptor structure
    Publication number: 20060160836
    Abstract: Estrogen receptor ligands, estrogen receptor polypeptide/ligand complexes, crystals of estrogen receptor polypeptide/ligand complexes, and related methods and software systems are disclosed.
    Type: Application
    Filed: January 18, 2006
    Publication date: July 20, 2006
    Inventors: Lidia Mosyak, Zhang Xu, Mark Stahl, Wah-Tung Hum, William Somers, Eric Manas
  • Substituted benzoxazoles as estrogenic agents
    Publication number: 20050239851
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R1, R2, R2a, R3, R3a, and R4, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 17, 2004
    Publication date: October 27, 2005
    Applicant: Wyeth
    Inventors: Michael Malamas, Robert McDevitt, Iwan Gunawan, Eric Manas, Michael Collini, Heather Harris, James Keith, Leo Albert, C. Lyttle
  • Substituted benzoxazoles as estrogenic agents
    Publication number: 20050080117
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein R1, R2, R2a, R3, R3a, and R4, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 19, 2004
    Publication date: April 14, 2005
    Applicant: Wyeth
    Inventors: Michael Malamas, Robert McDevitt, Iwan Gunawan, Eric Manas, Michael Collini
  • (Hydroxyphenyl)-1H-indole-3-carbaldehyde oxime derivatives as estrogenic agents
    Publication number: 20050059723
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure where R1, R2, R3, and R4 are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 9, 2004
    Publication date: March 17, 2005
    Applicant: Wyeth
    Inventors: Richard Mewshaw, Stephen Bowen, Eric Manas