Abstract: A centrifuge system including a centrifuge housing having a cavity at least partially surrounded by an outer shell, a central shaft extending into at least a portion of the cavity, a rotary motion source for rotating the centrifuge housing, and a filter concentrically positioned about the central shaft. The filter includes a first layer adjacent to a second layer, wherein the first and second layers are wound into a roll about a central longitudinal opening. The first layer may include at least one contaminant retention layer and the second layer may include at least one flow defining layer.