Abstract: An insect separating apparatus may include a sensor positioned to detect one or more insects when present within a test chamber. For example, the sensor may emit signals into the test chamber and receive reflected signals indicative of Doppler shifts caused by movement of the one or more insects. Based on information from the sensor, a computing device may determine a characteristic of the one or more insects in the chamber, such as a wing beat frequency, sex, or other characteristic. The computing device may instruct different responses based on the characteristic determined, such as activating an air mover to divert detected mosquitoes out of the test chamber in response to the determined characteristics matching those of female mosquitoes, or deactivating or maintaining the air mover in an inactive condition in response to the determined characteristics matching those of male mosquitoes, for example, to allow passage through the chamber into a collection receptacle.

Abstract: An intragastric balloon device including a deformable material is in an ingestible form for delivery to a stomach of a patient, expands in response to stimuli in the stomach, and degrades within a limited duration (such as 16 hours or some other value between 2 hours and 72 hours) to diminish to passable form in which remains of the intragastric balloon device are passable from the stomach. In an illustrative example, the deformable material is composed of silicone coated with parylene and encloses perfluoropentane fluid that transitions from liquid to gas due to stomach temperature to inflate the balloon in the stomach and occupy space in the stomach until a fuse of methacrylate erodes to unblock a vent conduit to permit escape of the perfluoropentane for deflating the balloon to diminish to passable form.

Abstract: Devices and methods are provided for drug delivery. The device may include a housing configured for intralumenal deployment into a human or animal subject and a reservoir contained within the housing and having an actuation end and a release end. The release end may include at least one outlet. A first drug formulation and a second drug formulation may be disposed within the reservoir and adjacent to each other and immiscible, or separated from each other by a first barrier. The device may also include a plug within the reservoir at the actuation end, the plug being movable toward the release end to drive the first and second drug formulations out of the reservoir. The device may also include an actuation system operably connected to the actuation end of the reservoir and configured to drive the plug toward the release end and release the drug formulations from the reservoir.

Abstract: A variety of embodiments of an at least partially flexible actuator are provided. The actuator includes a phase change material contained within an at least partially flexible enclosure of the actuator. Application of heat, using a heater of the actuator, to the phase change material causes the phase change material to boil, increasing the volume of the actuator and/or increasing a pressure within the actuator. As a result, the actuator can be used to apply a force to objects in an environment of interest. The actuator could be incorporated into a wearable blood pressure cuff and used to apply pressure to a body part of a wearer in order to detect a blood pressure of the wearer. In other examples, the actuator could be incorporated into a wearable device and used to secure a sensor or other elements of the device against skin of a wearer.

Abstract: A control unit, in a disclosed embodiment, includes a transceiver, memory, and a processor. The processor is coupled to the transceiver and memory and executes instructions from the memory to cause the control unit to receive a first transmission containing a certificate, verify the authenticity of the certificate, and, after verifying authenticity of the certificate, execute a public key agreement protocol to generate a first common secret encryption key, receive a second transmission containing an encrypted first public key that is encrypted by the first common secret encryption key, decrypt the encrypted first public key using the first common secret encryption key to determine the first public key, execute a public key agreement protocol to generate a second common secret encryption key, generate an operational key, encrypt the operational key using the second common secret encryption key, and transmit the encrypted operational key.

Abstract: Embodiments described herein may relate to an unmanned aerial vehicle (UAV) navigating to a target in order to provide medical support. An illustrative method involves a UAV (a) determining an approximate target location associated with a target, (b) using a first navigation process to navigate the UAV to the approximate target location, where the first navigation process generates flight-control signals based on the approximate target location, (c) making a determination that the UAV is located at the approximate target location, and (d) in response to the determination that the UAV is located at the approximate target location, using a second navigation process to navigate the UAV to the target, wherein the second navigation process generates flight-control signals based on real-time localization of the target.

Abstract: A key fob device, in one embodiment, includes a transceiver that receives and sends signals, a memory that stores a public key and a certificate of authenticity associated with the key fob device, and a processor coupled to the transceiver and memory. The processor is configured to execute instructions causing the key fob device to transmit the public key and the certificate of authenticity, execute a public key agreement protocol to generate a common secret encryption key, and receive an operation key encrypted with the common secret encryption key.

Abstract: Systems and methods can be provided to monitor insects (e.g., mosquitoes) in the field and gather data to ground truth one or more sensors or machine learning classification algorithms for classifying insects. A trap with various sensor capabilities can capture various insects and data pertaining to the captured insects. Some embodiments may enable offline identification of information by an entomologist or other individuals and use the identification information to ground-truth the one or more sensors. Using the trap with the various sensor capabilities increases the availability and diversity of training data for machine learning classification algorithms on the primary sensor.

Abstract: A camera attachment apparatus for attaching to a mobile computing device having an integrated camera includes a house, a slide plate, an aperture, and an illumination system. The housing has a shape to mount on the mobile computing device. The slide plate is disposed within the housing and has a stowed position and a deployed position. The aperture is disposed in the slide plate. The illumination system is disposed on the slide plate. The slide plate is configured to align the aperture over the integrated camera when moved to the deployed position and does not obstruct the integrated camera in the stowed position.

Abstract: Embodiments described herein may help to provide support via a fleet of unmanned aerial vehicles (UAVs). An illustrative medical-support system may include multiple UAVs, which are configured to provide support for a number of different situations. Further, the medical-support system may be configured to: (a) identify a remote situation, (b) determine a target location corresponding to the situation, (c) select a UAV from the fleet of UAVs, where the selection of the UAV is based on a determination that the selected UAV is configured for the identified situation, and (d) cause the selected UAV to travel to the target location to provide support.

Abstract: Embodiments described herein may relate to an unmanned aerial vehicle (UAV) navigating to a target in order to provide medical support. An illustrative method involves a UAV (a) determining an approximate target location associated with a target, (b) using a first navigation process to navigate the UAV to the approximate target location, where the first navigation process generates flight-control signals based on the approximate target location, (c) making a determination that the UAV is located at the approximate target location, and (d) in response to the determination that the UAV is located at the approximate target location, using a second navigation process to navigate the UAV to the target, wherein the second navigation process generates flight-control signals based on real-time localization of the target.

Abstract: Devices are provided to automatically access blood from beneath or within skin. These devices include an injector configured to drive a needle into the skin and subsequently to retract the needle from the skin. These devices additionally include a seal to which suction is applied. To drive the needle into the skin, the needle is first driven through the seal, creating at least one hole in the seal. The suction applied to the seal acts to draw blood from the puncture formed in the skin by the needle, through the at least one hole in the seal, and to a sensor, blood storage element, or other payload. These devices can be wearable and configured to automatically access blood from skin, for example, to access blood from the skin at one or more points in time while a wearer of a device is sleeping.

Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.

Abstract: A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface.

Abstract: A method and apparatus for gesture interaction with a photo-active painted surface is described. The method may include driving a spatial electromagnetic modulator to emit electromagnetic stimulation in the form of an image to cause photo-active paint to display the image. The method may also include capturing, with at least a camera of a painted surface display system, image data of the image displayed on the photo-active paint applied to a surface and a user motion performed relative to the image. The method may also include analyzing the captured image data to determine a sequence of one or more physical movements of the user relative to the image displayed on the photo-active paint. The method may also include determining, based on the analysis, that the user motion is indicative of a gesture, and driving the spatial electromagnetic modulator to update.

Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.

Abstract: A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.

Abstract: A system for needle-free drawing of blood is disclosed. A device can include an evacuated negative-pressure barrel with a membrane sealing an aperture at a distal end, and a housing affixed to a proximal end. An accelerator barrel can be positioned within the negative-pressure barrel and fixed to the housing, with an open proximal end in a chamber in the housing, and an open distal end aligned with the aperture. The chamber can be filled with pressurized gas, and a trigger valve can hydrostatically separate the chamber from the open proximal end of the accelerator barrel. A micro-particle positioned within the accelerator barrel can be accelerated to high speed by an abrupt surge of gas by releasing the trigger valve. The micro-particle can attain enough momentum to pierce the aperture membrane and penetrate adjacent dermal tissue. A resulting micro-emergence of blood can be drawn into the negative pressure barrel.

Abstract: Devices are provided to automatically access blood from beneath or within skin. These devices include an injector configured to drive a needle into the skin and subsequently to retract the needle from the skin. These devices additionally include a seal to which suction is applied. To drive the needle into the skin, the needle is first driven through the seal, creating at least one hole in the seal. The suction applied to the seal acts to draw blood from the puncture formed in the skin by the needle, through the at least one hole in the seal, and to a sensor, blood storage element, or other payload. These devices can be wearable and configured to automatically access blood from skin, for example, to access blood from the skin at one or more points in time while a wearer of a device is sleeping.

Abstract: A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface.