Abstract: The invention relates to substances which are capable of protecting FGF-2, to a composition for preventing or controlling degradation of FGF-2, and a method of protecting FGF-2 in the skin from degradation. In particular, the invention relates to an extract of Hibiscus Abelmoschus or ambrette, a rebokza extract, a gougizi berry extract, a banha extract, a lessonia extract, a mustard flour extract, a wooyin extract, a barley extract, and/or a sesame extract, in amounts effective to protect FGF-2 from its degradation. Further, the present invention allows the extracellular matrix to be restructured, particularly at the dermis, which is useful, for example, for controlling aging.

Abstract: The invention relates to plant extracts for stimulating the synthesis of hyaluronan synthase, particularly the synthesis of hyaluronan synthase 2 (HAS2). Specific aims of the invention are to increase firmness and/or elasticity and/or tissue moisturization, and/or increase the skin barrier effect, and/or increase tissue resilience, and/or modulate angiogenesis, or the neocreation of blood capillaries, and/or improve healing, and/or cell proliferation, migration or differentiation, and/or skin atrophy, and/or intended to combat the effects of ageing on the skin, and in particular to combat the loss of firmness of the skin observed in the course of ageing, and/or atrophied scars.

Abstract: The invention relates to the use of para-coumaric acid or para-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions, specifically to the use of at least one compound derived from para-coumaric acid having a general formula (I) below: in which, especially, Z represents an oxygen or an —NH— group; X and Y are identical and each represent a CH or CH2 group, as an active principle with depigmenting, free-radical-scavenging and/or antiinflammatory activity. The invention also relates to the use of the above compounds for cosmetic care or for the preparation of a pharmaceutical composition, especially for depigmenting an area of skin, having antiradical and/or antiinflammatory activity.

Abstract: at least one aurone or a natural or synthetic derivative of aurone, or an analogue of aurone, in which the independent phenyl ring can be substituted by a heterocycle of pyrrole, imidazole, triazole, pyridine, furan, or thiophene type, is disclosed as a cosmetic agent, or as an active substance, for the manufacture either of a cosmetic composition, or of a pharmaceutical composition, notably a dermatological composition, having a melanogenesis-inhibiting activity or a depigmenting activity, or an anti-tyrosinase activity.

Abstract: The invention discloses a method for tinting, for coloring skin, or for increasing the tanned appearance of skin comprising the use of an extract of a plant from the family of Compositae or Asteraceae, preferably an extract of chicory (Cichorium intybus L.), and a method of screening a plant for the manufacture of a cosmetic composition for coloring, particularly for tinting, at least one part of skin.

Abstract: The invention discloses a cross-linked polymer of at least one carbohydrate component comprising at least one primary alcohol function in particular for the manufacture of a composition which is intended to be applied onto the skin to obtain a tensing and/or toning effect.

Abstract: a cell culture device is disclosed having at least one cell-supporting layer of porous material obtained by dehydration of an aqueous gel which is poured directly either into said well bottom or into the bottom of a cradle or insert of a size which is adapted for being insertable into the volume of the well, thereby enabling by a robot or an automaton itself commanded by you computer.

Abstract: The invention relates to active principles which are capable of inducing the conversion of inactive TGFb-Latent into active TGFb. The invention relates in particular to the use of such an extract for the manufacture of a composition for increasing the concentration of active TGFb1 in the skin, notably in the dermis. The present invention also relates to the uses which are derived from said use, as well as to cosmetic or pharmaceutical compositions which comprise said extract.

Abstract: The invention relates to novel hydrated lamellar phases or liposomes which contain either polyethylenimine, or a substance which stimulates intracellular penetration selected from the group consisting of: i) a fatty monoamine of carbon-containing chain length of between C10 and C18; ii) a cationic polymer, optionally at least one fluorescent compound which is essentially inert with respect to the intracellular penetration, which enables this penetration to be visualised. These liposomes are very useful in cosmetics or in pharmacy for stimulating the intracellular penetration of a substance or active principle.

Abstract: The invention relates to the use of a Rhodiola crenulata extract, via the topical route, for increasing the energy metabolism of the cutaneous tissues of a subject. The invention relates notably to topical compositions which comprise an active agent for increasing the energy metabolism of the cutaneous tissues of a subject, said active agent being a Rhodiola crenulata extract. The present invention enables making a cosmetic care such as fighting against, or slowing down or preventing the loosening of the cutaneous tissue, increasing the plasticity of the cutaneous tissue, exerting an anti-wrinkle effect or slowing down or preventing the appearance of wrinkles, fighting against, slowing down or preventing the appearance of acne, exerting a depigmenting effect of the cutaneous tissue, in particular of the skin, and promoting desquamation of the cutaneous tissue (or “peeling”).

Abstract: The invention relates to the use of CD14+ monocytes for the production of dendritic cells. The invention comprises the use of CD14+ monocytes isolated from peripheral circulating blood for obtaining, by differentiation, at least one mixed population of Langerhans cells and interstitial dendritic cells, both Langerhans cells and interstitial dendritic cells being preconditioned and undifferentiated, and/or differentiated and immature, and/or mature, and/or interdigitated. The invention comprises their use in suspension, monolayer and three-dimensional cell and tissue models. The invention comprises the use of these cells and of these models as study models for the assessment of immunotoxicity/immunotolerance, for the development of cosmetic and pharmaceutical active principles and for the development and implementation of methods of cell and tissue therapy.

Abstract: The invention relates to the stimulation of the activity of an isoform of lysyl oxidase, and more particularly of the LOX (lysyl oxidase) isoform.

Abstract: The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (Iysyl oxidase-like) isoform.

Abstract: The invention relates to novel amphiphilic complexes, a method for their preparation, and the compositions containing them. Said amphiphilic complexes result from the reaction, at a temperature between ambient temperature and 80° C., between a protein or polypeptide whose average molecular mass is greater than or equal to 5,000 Daltons and a fatty chain whose carbon atom number is between 4 and 30 selected from fatty acid, fatty alcohol, fatty amine, with the exclusion of undecylenic acid ; the protein or polypeptide/fatty chain weight ratio ranging from 1000/1 to 1/10.

Abstract: The invention relates mainly to a particle comprising at least one biopolymer which is degradable under the effect of an electromagnetic wavelength, notably the wavelength of which is in the spectrum of the wavelengths emitted by the sun, this biopolymer comprising nucleosides. The invention also relates to compositions containing such particles with the aim of delivering an active principle.

Abstract: The invention relates to a cosmetic or dermopharmaceutical composition, as well as these uses.

Abstract: An object of the invention is a method of identifying an eventual modification of at least one biological parameter.

Abstract: An aim of the invention is a method of identifying an eventual modification of at least one biological parameter.

Abstract: The invention relates mainly to a method of testing the activity of a potentially active substance to inhibit the enzymatic activity of phospholipase A2.

Abstract: The invention relates to active ingredients capable of stimulating direct or indirect expression of type 2 human beta-defensins and/or type 3 human beta-defensins.